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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

Comprehensive Overview of 2-(Dimethylamino)propanoic Acid (CAS No. 19701-89-4): Properties, Applications, and Industry Insights

2-(Dimethylamino)propanoic acid (CAS No. 19701-89-4) is a versatile organic compound with a growing presence in pharmaceutical, agrochemical, and specialty chemical industries. This amino acid derivative is characterized by its unique molecular structure, featuring a dimethylamino group attached to the α-carbon of propanoic acid. Its chemical formula C5H11NO2 and molecular weight of 117.15 g/mol make it an intermediate of significant interest for researchers exploring biocompatible materials and drug delivery systems.

Recent advancements in green chemistry have spotlighted 2-(dimethylamino)propanoic acid as a potential building block for sustainable synthesis. Industry reports indicate a 22% annual growth in demand for such functionalized amino acids, driven by their applications in biodegradable polymers and pH-responsive materials. The compound's zwitterionic nature at physiological pH contributes to its exceptional water solubility, a property highly valued in formulation science.

Analytical studies of CAS 19701-89-4 reveal distinctive spectroscopic properties that facilitate its identification. The infrared spectrum typically shows strong absorption bands at 1720 cm^-1 (C=O stretch) and 1580 cm^-1 (N-H bend), while NMR spectroscopy displays characteristic signals at δ 2.3 (N-CH₃) and δ 3.8 (CH-N) in D₂O. These structural features enable precise quality control during manufacturing processes.

In pharmaceutical applications, 2-(dimethylamino)propanoic acid serves as a crucial precursor for prodrug development. Its tertiary amine functionality allows for efficient salt formation with various therapeutic agents, improving their bioavailability and tissue penetration. Recent patent filings (2022-2023) demonstrate innovative uses in targeted drug delivery systems, particularly for CNS-active compounds requiring enhanced blood-brain barrier permeability.

The compound's role in crop protection formulations has gained attention in agricultural research. When incorporated into foliar sprays, derivatives of 2-(dimethylamino)propanoic acid demonstrate improved leaf adhesion and rainfastness compared to conventional additives. Field trials conducted in 2023 showed a 15-20% reduction in active ingredient wash-off, addressing growing concerns about environmental runoff in modern farming practices.

Material scientists are exploring 19701-89-4 as a monomer for smart polymer synthesis. Its pH-responsive behavior enables the creation of membranes with tunable permeability characteristics, applicable in separation technologies and controlled release devices. Recent publications highlight successful incorporation into thermoresponsive hydrogels that undergo reversible phase transitions near physiological temperatures.

Quality specifications for 2-(dimethylamino)propanoic acid typically require ≥98% purity (HPLC), with strict limits on residual solvents. The white crystalline powder exhibits hygroscopic properties, necessitating proper storage in airtight containers at 2-8°C. Leading manufacturers employ continuous flow chemistry techniques to enhance production efficiency while minimizing process impurities.

Emerging research directions include the compound's potential in ionic liquid formulations and electrolyte additives for energy storage applications. Preliminary data suggests improved cycle stability in lithium-ion batteries when using 19701-89-4 derivatives as cathode interface modifiers, aligning with global trends in renewable energy storage solutions.

Regulatory status of 2-(dimethylamino)propanoic acid varies by region, with most jurisdictions classifying it as a non-hazardous substance when handled properly. However, comprehensive REACH compliance documentation and proper SDS protocols remain essential for commercial distribution. The compound's environmental fate studies indicate rapid biodegradation under aerobic conditions, supporting its eco-friendly profile.

Market analysts project steady growth for CAS 19701-89-4 through 2028, particularly in Asia-Pacific regions where pharmaceutical outsourcing activities are expanding. Current pricing trends reflect increasing demand, with technical-grade material trading at $120-150/kg and research-grade samples at $250-300/kg. Strategic partnerships between fine chemical suppliers and CDMO organizations are reshaping the supply chain landscape for this specialty intermediate.

For researchers investigating structure-activity relationships, 2-(dimethylamino)propanoic acid offers valuable insights into steric effects and electronic modulation in medicinal chemistry. Its conformational flexibility allows diverse molecular interactions, making it a versatile scaffold for lead optimization in drug discovery programs targeting GPCRs and ion channels.

Advanced purification techniques such as preparative HPLC and crystallization optimization have significantly improved the availability of high-purity 19701-89-4 material. These advancements support the compound's expanding role in high-value applications where isomeric purity and chiral integrity are critical performance factors.

• 22149-55-9(Alanine, N,N-bis(carboxymethyl)-)
• 2812-34-2(L-Serine, N,N-dimethyl-)
• 126576-99-6((2R)-2-(dimethylamino)-3-hydroxypropanoic acid)
• 17087-29-5((S)-(1-Carboxy-aethyl)-trimethyl-ammonium; Betain)
• 16708-13-7(2-(dimethylamino)propanoic acid hydrochloride)
• 157431-09-9((2R)-2-(dimethylamino)propanoic acid)
• 77554-84-8(L-Alanine,N,N-bis(carboxymethyl)-, sodium salt (1:?))
• 29578-05-0(Methylglycine Diacetic Acid)
• 2812-31-9((2S)-2-(dimethylamino)propanoic acid)
• 170492-24-7(L-Alanine,N,N-bis(carboxymethyl)-, sodium salt (1:3))