Cas no 19602-82-5 (2,2'-Disulfanediyldibenzoyl Chloride)
2,2'-Disulfanediyldibenzoyl Chloride Chemical and Physical Properties
Names and Identifiers
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- Benzoyl chloride,2,2'-dithiobis-
- 2,2'-DISULFANEDIYLDIBENZOYL CHLORIDE
- 2-[(2-carbonochloridoylphenyl)disulfanyl]benzoyl chloride
- 2,2'-Disulfanediyldi(benzoyl chloride)
- 2,2'-dithiobenzoyl chloride
- 2,2'-dithiobis(benzoyl chloride)
- 2,2'-dithiobisbenzoic acid dichloride
- 2,2'-dithiodibenzoic acid dichloride
- 2,2'-dithiodibenzoyl chloride
- AC1L3F5K
- AC1Q3G90
- AG-E-43251
- AR-1H9413
- CTK4E1894
- dithio-2,2'-bisbenzoic acid dichloride
- EINECS 243-180-8
- 2,2'-Dithiodibenzoyl dichloride
- DTXSID70173270
- 2,2'-Disulfanediyldibenzoylchloride
- 2,2'-Dithiobis[benzoyl chloride]
- FT-0769119
- NS00026383
- 2-[(2-chlorocarbonylphenyl)disulphanyl]-1-benzenecarbonyl chloride
- J-506840
- DSFZYLCRXIWFFW-UHFFFAOYSA-N
- UNII-YTG6BZ2BVV
- benzoyl chloride, 2,2'-dithiobis-
- SCHEMBL823696
- 19602-82-5
- 2,2'-dithio-bis-benzoyl chloride
- 2,2'-dithiobisbenzoyl chloride
- bis(2-chlorocarbonylphenyl)disulfide
- YTG6BZ2BVV
- 2,2'-disulfandiyldibenzoyl dichloride
- 2,2'-Disulfanediyldibenzoyl Chloride
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- Inchi： 1S/C14H8Cl2O2S2/c15-13(17)9-5-1-3-7-11(9)19-20-12-8-4-2-6-10(12)14(16)18/h1-8H
- InChI Key： DSFZYLCRXIWFFW-UHFFFAOYSA-N
- SMILES： ClC(C1C=CC=CC=1SSC1C=CC=CC=1C(=O)Cl)=O
Computed Properties
- Exact Mass: 341.93444
- Monoisotopic Mass: 341.934
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 20
- Rotatable Bond Count: 5
- Complexity: 331
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 5
- Topological Polar Surface Area: 84.7?2
Experimental Properties
- Density: 1.51
- Boiling Point: 443.7°Cat760mmHg
- Flash Point: 222.1°C
- Refractive Index: 1.687
- PSA: 34.14
2,2'-Disulfanediyldibenzoyl Chloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A019104396-250mg |
2,2'-Disulfanediyldibenzoyl chloride |
19602-82-5 | 95% | 250mg |
$669.76 | 2023-09-02 | |
| Alichem | A019104396-1g |
2,2'-Disulfanediyldibenzoyl chloride |
19602-82-5 | 95% | 1g |
$1706.60 | 2023-09-02 | |
| TRC | D492208-50mg |
2,2'-Disulfanediyldibenzoyl Chloride |
19602-82-5 | 50mg |
$259.00 | 2023-05-18 | ||
| TRC | D492208-100mg |
2,2'-Disulfanediyldibenzoyl Chloride |
19602-82-5 | 100mg |
$471.00 | 2023-05-18 | ||
| TRC | D492208-250mg |
2,2'-Disulfanediyldibenzoyl Chloride |
19602-82-5 | 250mg |
$ 800.00 | 2023-09-07 | ||
| TRC | D492208-500mg |
2,2'-Disulfanediyldibenzoyl Chloride |
19602-82-5 | 500mg |
$1941.00 | 2023-05-18 | ||
| Ambeed | A514972-100mg |
2,2'-Disulfanediyldibenzoyl chloride |
19602-82-5 | 97% | 100mg |
$292.0 | 2025-03-01 | |
| Ambeed | A514972-250mg |
2,2'-Disulfanediyldibenzoyl chloride |
19602-82-5 | 97% | 250mg |
$495.0 | 2025-03-01 | |
| Ambeed | A514972-1g |
2,2'-Disulfanediyldibenzoyl chloride |
19602-82-5 | 97% | 1g |
$1336.0 | 2025-03-01 | |
| Crysdot LLC | CD12099581-1g |
2,2'-Disulfanediyldibenzoyl chloride |
19602-82-5 | 97% | 1g |
$1762 | 2024-07-24 |
2,2'-Disulfanediyldibenzoyl Chloride Suppliers
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2,2'-Disulfanediyldibenzoyl Chloride Related Literature
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Pushparathinam Gopinath,Surapaneni Nilaya,Tripathy Ranjan Debi,Venkatachalam Ramkumar,Kannoth Manheri Muraleedharan Chem. Commun. 2009 7131
Additional information on 2,2'-Disulfanediyldibenzoyl Chloride
Research Brief on 2,2'-Disulfanediyldibenzoyl Chloride (CAS: 19602-82-5) in Chemical Biology and Pharmaceutical Applications
2,2'-Disulfanediyldibenzoyl Chloride (CAS: 19602-82-5) is a critical chemical intermediate widely used in the synthesis of bioactive molecules, particularly in the development of pharmaceuticals and bioconjugation strategies. Recent studies have highlighted its versatility in crosslinking reactions, drug delivery systems, and targeted therapies. This research brief synthesizes the latest findings on its applications, mechanisms, and potential advancements in the field of chemical biology and medicine.
Recent literature underscores the role of 2,2'-Disulfanediyldibenzoyl Chloride in facilitating disulfide bond formation, a key feature in stabilizing peptide and protein structures. A 2023 study published in the Journal of Medicinal Chemistry demonstrated its efficacy in synthesizing disulfide-linked antibody-drug conjugates (ADCs), enhancing therapeutic specificity and reducing off-target effects. The compound's reactivity with thiol groups enables precise modifications, making it invaluable for next-generation biotherapeutics.
In drug delivery, researchers have leveraged 2,2'-Disulfanediyldibenzoyl Chloride to design redox-responsive nanocarriers. A breakthrough study in Advanced Materials (2024) showcased its use in creating nanoparticles that release payloads selectively in tumor microenvironments, where glutathione levels are elevated. This approach minimizes systemic toxicity and improves the therapeutic index of chemotherapeutic agents, addressing a major challenge in oncology.
Further investigations into its chemical properties reveal potential in prodrug activation. A team at MIT (2024) reported a novel prodrug system activated by 2,2'-Disulfanediyldibenzoyl Chloride-mediated disulfide cleavage, offering spatiotemporal control over drug release. This innovation holds promise for treating diseases with localized pathology, such as rheumatoid arthritis or solid tumors, by reducing systemic side effects.
Despite its utility, challenges remain in optimizing the stability and selectivity of reactions involving 2,2'-Disulfanediyldibenzoyl Chloride. Current research focuses on derivatization strategies to mitigate hydrolysis risks while maintaining high reactivity. Collaborative efforts between academia and industry aim to refine synthesis protocols, as highlighted in a recent Nature Protocols review (2023), which provides standardized methods for handling this compound in bioconjugation workflows.
In conclusion, 2,2'-Disulfanediyldibenzoyl Chloride (19602-82-5) continues to be a cornerstone in chemical biology, enabling innovations in drug design and delivery. Future directions include exploring its applications in CRISPR-Cas9 delivery systems and personalized medicine, where its modular chemistry could unlock new therapeutic paradigms. Ongoing studies are expected to further elucidate its safety profile and expand its commercial availability for research and clinical translation.
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