Cas no 1955540-34-7 (2,2-difluorospiro[2.3]hexan-5-amine;hydrochloride)
2,2-Difluorospiro[2.3]hexan-5-amine hydrochloride is a fluorinated spirocyclic amine compound with a unique structural motif, offering potential utility in pharmaceutical and agrochemical applications. The incorporation of difluoromethylene and spirocyclic moieties enhances its metabolic stability and lipophilicity, making it a valuable intermediate in drug discovery. The hydrochloride salt form improves solubility and handling properties. Its rigid spirocyclic framework may contribute to selective binding interactions in biological systems. The compound’s synthetic versatility allows for further functionalization, enabling exploration of structure-activity relationships. Careful control of stereochemistry during synthesis ensures high purity, which is critical for research and development purposes. This compound is typically handled under inert conditions due to its sensitivity.
![2,2-difluorospiro[2.3]hexan-5-amine;hydrochloride structure](https://ossimg.kuujia.com/scimg/1956000/1955540-34-7x500.png)
1955540-34-7 structure
Product Name:2,2-difluorospiro[2.3]hexan-5-amine;hydrochloride
CAS No:1955540-34-7
MF:C6H10ClF2N
MW:169.60010766983
MDL:MFCD30181152
CID:4631484
PubChem ID:122164180
Update Time:2025-07-23
2,2-difluorospiro[2.3]hexan-5-amine;hydrochloride Chemical and Physical Properties
Names and Identifiers
-
- 1,1-difluorospiro[2.3]hexan-5-amine hydrochloride
- 2,2-difluorospiro[2.3]hexan-5-amine;hydrochloride
- D73460
- 1,1-DIFLUOROSPIRO[2.3]HEXAN-5-AMINE HCL
- 2,2-Difluorospiro[2.3]hexan-5-amine hydrochloride
- EN300-301582
- 2,2-difluorospiro[2.3]hexan-5-amine HCl
- 1955540-34-7
- 1,1-difluorospiro[2.3]hexan-5-aminehydrochloride
- SCHEMBL22690897
- MFCD30181152
- CS-0067428
-
- MDL： MFCD30181152
- Inchi： 1S/C6H9F2N.ClH/c7-6(8)3-5(6)1-4(9)2-5;/h4H,1-3,9H2;1H
- InChI Key： WGDAQAXOMRICLG-UHFFFAOYSA-N
- SMILES： Cl.FC1(CC21CC(C2)N)F
Computed Properties
- Exact Mass: 169.0469833g/mol
- Monoisotopic Mass: 169.0469833g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 149
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 26
2,2-difluorospiro[2.3]hexan-5-amine;hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM435759-1g |
1,1-difluorospiro[2.3]hexan-5-amine hydrochloride |
1955540-34-7 | 95%+ | 1g |
$2340 | 2022-12-31 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1138068-100mg |
1,1-Difluorospiro[2.3]hexan-5-amine hydrochloride |
1955540-34-7 | 97% | 100mg |
￥2448 | 2023-04-15 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1138068-250mg |
1,1-Difluorospiro[2.3]hexan-5-amine hydrochloride |
1955540-34-7 | 97% | 250mg |
￥3910 | 2023-04-15 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1138068-500mg |
1,1-Difluorospiro[2.3]hexan-5-amine hydrochloride |
1955540-34-7 | 97% | 500mg |
￥6055 | 2023-04-15 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1138068-1g |
1,1-Difluorospiro[2.3]hexan-5-amine hydrochloride |
1955540-34-7 | 97% | 1g |
￥9079 | 2023-04-15 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1138068-5g |
1,1-Difluorospiro[2.3]hexan-5-amine hydrochloride |
1955540-34-7 | 97% | 5g |
￥25142 | 2023-04-15 | |
| Enamine | EN300-301582-0.05g |
1,1-difluorospiro[2.3]hexan-5-amine hydrochloride |
1955540-34-7 | 95.0% | 0.05g |
$222.0 | 2025-03-19 | |
| Enamine | EN300-301582-0.1g |
1,1-difluorospiro[2.3]hexan-5-amine hydrochloride |
1955540-34-7 | 95.0% | 0.1g |
$331.0 | 2025-03-19 | |
| Enamine | EN300-301582-0.25g |
1,1-difluorospiro[2.3]hexan-5-amine hydrochloride |
1955540-34-7 | 95.0% | 0.25g |
$474.0 | 2025-03-19 | |
| Enamine | EN300-301582-0.5g |
1,1-difluorospiro[2.3]hexan-5-amine hydrochloride |
1955540-34-7 | 95.0% | 0.5g |
$746.0 | 2025-03-19 |
2,2-difluorospiro[2.3]hexan-5-amine;hydrochloride Related Literature
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Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
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Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
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Raktani Bikshapathi,Sai Prathima Parvathaneni,Vaidya Jayathirtha Rao Green Chem., 2017,19, 4446-4450
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Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699
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Xiang Liu,Qian Sun,A. B. Djuri?i?,Maohai Xie,Baohu Dai,Jinyao Tang,Charles Surya,Changzhong Liao,Kaimin Shih RSC Adv., 2015,5, 100783-100789
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