Cas no 195372-57-7 (N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide)

N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide is a halogenated acetamide derivative with potential applications in organic synthesis and pharmaceutical research. Its structure, featuring both bromo and chloro substituents, makes it a versatile intermediate for constructing complex molecules, particularly in medicinal chemistry. The compound exhibits high reactivity due to the presence of the chloroacetyl group, enabling efficient nucleophilic substitution reactions. Its well-defined molecular framework ensures consistent performance in synthetic pathways, while its stability under standard conditions facilitates handling and storage. Researchers value this compound for its utility in developing biologically active compounds, including agrochemicals and pharmacophores. Proper safety protocols should be followed due to its halogenated nature.
N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide structure
195372-57-7 structure
Product Name:N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide
CAS No:195372-57-7
MF:C8H6BrCl2NO
MW:282.949339389801
MDL:MFCD00157385
CID:116753
PubChem ID:3303442
Update Time:2025-11-07

N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide Chemical and Physical Properties

Names and Identifiers

    • N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide
    • Acetamide,N-(4-bromo-2-chlorophenyl)-2-chloro-
    • AC1MNG4S
    • AC1Q3TIS
    • ALBB-002285
    • BBL013581
    • CTK4E1740
    • MolPort-000-871-753
    • STK408452
    • AKOS B015653
    • ART-CHEM-BB B015653
    • CHEMBRDG-BB 3015653
    • N-(4-bromo-2-chlorophenyl)-2-chloroacetamide(SALTDATA: FREE)
    • MFCD00157385
    • DTXSID30391251
    • CS-0206197
    • Z57320466
    • EN300-24570
    • 4'-BROMO-2,2'-CHLOROACETANILIDE
    • AKOS000305608
    • 195372-57-7
    • VS-03873
    • AKOS BBS-00003993
    • MDL: MFCD00157385
    • Inchi: 1S/C8H6BrCl2NO/c9-5-1-2-7(6(11)3-5)12-8(13)4-10/h1-3H,4H2,(H,12,13)
    • InChI Key: CHGAKXUQWOXUKE-UHFFFAOYSA-N
    • SMILES: BrC1C=CC(=C(C=1)Cl)NC(CCl)=O

Computed Properties

  • Exact Mass: 280.90100
  • Monoisotopic Mass: 280.90098g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 191
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.9
  • Topological Polar Surface Area: 29.1?2

Experimental Properties

  • PSA: 29.10000
  • LogP: 3.35280

N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide Security Information

  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT

N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide Customs Data

  • HS CODE:2924299090
  • Customs Data:

    China Customs Code:

    2924299090

    Overview:

    2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Additional information on N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide

N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide: A Comprehensive Overview

N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide, also known by its CAS number 195372-57-7, is a compound of significant interest in the fields of organic chemistry and materials science. This compound is characterized by its unique structure, which combines a bromine atom at the para position and a chlorine atom at the ortho position on the phenyl ring, along with a 2-chloroacetamide group attached to the nitrogen atom. The combination of these substituents imparts distinctive chemical and physical properties to the molecule, making it a valuable subject for research and potential applications.

The synthesis of N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide typically involves multi-step organic reactions, including nucleophilic substitution and acylation. Recent advancements in catalytic methods have enabled more efficient and selective syntheses, reducing production costs and minimizing environmental impact. These developments are particularly relevant in the context of green chemistry, where sustainable practices are increasingly prioritized.

One of the most promising applications of this compound lies in its potential as a precursor for advanced materials. Researchers have explored its use in the development of novel polymers and hybrid materials with tailored electronic properties. For instance, studies have demonstrated that incorporating N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide into polymer matrices can enhance thermal stability and mechanical strength, making it a candidate for high-performance materials in aerospace and automotive industries.

In addition to its material science applications, this compound has shown potential in biological systems. Recent studies have investigated its role as a bioactive agent, particularly in enzyme inhibition assays. The presence of halogen atoms in its structure contributes to its ability to interact with biological targets, offering possibilities for drug discovery. However, further research is required to fully understand its pharmacokinetics and toxicity profiles.

The chemical stability of N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide under various conditions has also been a focus of recent investigations. Studies have revealed that the compound exhibits remarkable stability under thermal and oxidative stress, which is advantageous for its use in demanding environments. This property is particularly valuable in industrial settings where prolonged exposure to harsh conditions is common.

From an environmental perspective, understanding the degradation pathways of this compound is crucial for assessing its ecological impact. Research has shown that under specific conditions, such as UV light exposure or microbial action, the compound undergoes degradation into less complex molecules. These findings are essential for developing strategies to mitigate any adverse environmental effects associated with its use.

In conclusion, N-(4-Bromo-2-chlorophenyl)-2-chloroacetamide (CAS No: 195372-57-7) is a versatile compound with diverse applications across multiple disciplines. Its unique structure, combined with recent advancements in synthesis and application techniques, positions it as a key player in both academic research and industrial innovation. As ongoing studies continue to uncover new insights into its properties and potential uses, this compound is poised to make significant contributions to various fields in the coming years.

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