Cas no 19451-11-7 (Iodocyclopropane)

Iodocyclopropane is a halogenated cyclic hydrocarbon with the molecular formula C?H?I, characterized by a three-membered cyclopropane ring substituted with an iodine atom. This compound is primarily utilized as a versatile intermediate in organic synthesis, particularly in cyclopropanation reactions and ring-opening transformations. Its strained ring structure enhances reactivity, making it valuable for constructing complex molecular frameworks. Iodocyclopropane is also employed in cross-coupling reactions and as a precursor for further functionalization. The iodine substituent facilitates nucleophilic substitution, enabling selective modifications. Handling requires caution due to its light sensitivity and potential instability. Proper storage under inert conditions is recommended to maintain purity and reactivity.
Iodocyclopropane structure
Iodocyclopropane structure
Product Name:Iodocyclopropane
CAS No:19451-11-7
MF:C3H5I
MW:167.976273298264
MDL:MFCD20621267
CID:1386901
PubChem ID:640653
Update Time:2025-06-09

Iodocyclopropane Chemical and Physical Properties

Names and Identifiers

    • Cyclopropane, iodo-
    • Cyclopropyl iodide
    • Iodocyclopropane
    • 1-Iodocyclopropane
    • cyclopropyliodide
    • VLODBNNWEWTQJX-UHFFFAOYSA-N
    • InChI=1/C3H5I/c4-3-1-2-3/h3H,1-2H
    • MFCD20621267
    • AKOS024462864
    • AC5127
    • SY046875
    • A936748
    • BS-12655
    • 1-Iodocyclopropane; Iodocyclopropane pound>>Cyclopropyliodide
    • SCHEMBL1354775
    • 19451-11-7
    • BCP29363
    • EN300-214303
    • MDL: MFCD20621267
    • Inchi: 1S/C3H5I/c4-3-1-2-3/h3H,1-2H2
    • InChI Key: VLODBNNWEWTQJX-UHFFFAOYSA-N
    • SMILES: IC1CC1

Computed Properties

  • Exact Mass: 167.94315
  • Monoisotopic Mass: 167.94360g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 4
  • Rotatable Bond Count: 0
  • Complexity: 22.5
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 0
  • XLogP3: 2.1

Experimental Properties

  • PSA: 0

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Iodocyclopropane Suppliers

Amadis Chemical Company Limited
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(CAS:19451-11-7)Iodocyclopropane
Order Number:A936748
Stock Status:in Stock
Quantity:250mg/1g/5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 15:20
Price ($):162.0/405.0/1341.0

Additional information on Iodocyclopropane

Iodocyclopropane (CAS No. 19451-11-7): An Overview of Its Properties, Applications, and Recent Research Advances

Iodocyclopropane (CAS No. 19451-11-7) is a cyclic organic compound characterized by its unique molecular structure, which consists of a three-membered ring with an iodine atom attached. This compound has garnered significant attention in the fields of organic chemistry, medicinal chemistry, and materials science due to its potential applications and intriguing chemical properties.

The molecular formula of iodocyclopropane is C3H5I, and its molecular weight is approximately 152.07 g/mol. The compound's high reactivity and unique electronic properties make it a valuable intermediate in various synthetic pathways. In recent years, researchers have explored the use of iodocyclopropane in the synthesis of complex organic molecules, particularly those with biological relevance.

Iodocyclopropane exhibits notable reactivity due to the strain inherent in the three-membered ring and the presence of the iodine atom. This strain can be harnessed to facilitate ring-opening reactions, which are crucial in the synthesis of a wide range of compounds. For instance, studies have shown that iodocyclopropane can undergo ring-opening reactions with nucleophiles such as amines and thiols, leading to the formation of substituted propargylamines and propargylthiols, respectively.

In the realm of medicinal chemistry, iodocyclopropane has been investigated for its potential as a building block in the development of novel drugs. The iodine atom can serve as a handle for further functionalization, allowing chemists to introduce various substituents that can modulate the biological activity of the final product. Recent research has focused on using iodocyclopropane-derived compounds in the design of inhibitors for specific enzymes and receptors, which could have therapeutic applications in diseases such as cancer and neurodegenerative disorders.

Beyond its use in medicinal chemistry, iodocyclopropane has also found applications in materials science. The compound's reactivity and ability to form stable derivatives make it an attractive candidate for the synthesis of functional materials with tailored properties. For example, researchers have explored the use of iodocyclopropane-based polymers in the development of advanced materials for electronic and optical devices.

The environmental impact of chemical compounds is an increasingly important consideration in their development and application. Studies on the environmental fate and toxicity of iodocyclopropane are limited but ongoing. Preliminary data suggest that while iodocyclopropane is not highly toxic at low concentrations, its reactivity may pose risks if not handled properly. Therefore, appropriate safety measures should be taken during its synthesis and use.

In conclusion, iodocyclopropane (CAS No. 19451-11-7) is a versatile compound with a wide range of applications in organic synthesis, medicinal chemistry, and materials science. Its unique chemical properties make it an important intermediate in various synthetic pathways, and ongoing research continues to uncover new possibilities for its use. As research progresses, it is likely that iodocyclopropane-based compounds will play an increasingly significant role in advancing scientific knowledge and developing innovative solutions to real-world problems.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:19451-11-7)Iodocyclopropane
A936748
Purity:99%/99%/99%
Quantity:250mg/1g/5g
Price ($):162.0/405.0/1341.0
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