Cas no 193978-23-3 (4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane)

4,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane is a heterocyclic boronic ester widely used as a key intermediate in Suzuki-Miyaura cross-coupling reactions. Its stable dioxaborolane structure enhances shelf life and handling compared to boronic acids, while the thiophene moiety facilitates applications in conjugated polymer and pharmaceutical synthesis. The compound exhibits high reactivity with aryl halides, enabling efficient C-C bond formation under mild conditions. Its crystalline solid form ensures precise measurement and reproducibility in organic transformations. The electron-rich thiophene group further enhances its utility in constructing π-extended systems for optoelectronic materials. Suitable for controlled environments due to moisture sensitivity, it is a preferred reagent in advanced synthetic chemistry.
4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane structure
193978-23-3 structure
Product Name:4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane
CAS No:193978-23-3
MF:C10H15BO2S
MW:210.100901842117
MDL:MFCD05663878
CID:66462
PubChem ID:10703628
Update Time:2025-06-17

4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane Chemical and Physical Properties

Names and Identifiers

    • 4,4,5,5-Tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane
    • 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene
    • Thiophene-2-boronic acid pinacol ester
    • 2-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-4-trifluoromethyl-phenylamine
    • 2-(Thiopheneboronic acid)pinacol Ester
    • 2-Thiopheneboronic acid pinacol ester
    • 4,4,5,5-tetramethyl-2-thiophen-2-yl-1,3,2-dioxaborolane
    • 2-(thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-di
    • 2-thiophene boronic pinacol ester
    • 4,4,5,5-Tetramethyl-2-(thien-2-yl)-1,3,2-dioxaborolane
    • 4,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane
    • 2-(thiophene-2-yl)-4,4,5,5-tetraMethyl-[1,3,2]dioxaborolane
    • Thiophene-2-boronic acid pinacol ester 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene
    • THIOPHENE-2-BORONIC ACID, PINACOL ESTER
    • 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-(2-thienyl)-
    • PubChem18441
    • AMTB522
    • 4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane
    • MDL： MFCD05663878
    • Inchi： 1S/C10H15BO2S/c1-9(2)10(3,4)13-11(12-9)8-6-5-7-14-8/h5-7H,1-4H3
    • InChI Key： FFZHICFAHSDFKZ-UHFFFAOYSA-N
    • SMILES： S1C=CC=C1B1OC(C)(C)C(C)(C)O1

Computed Properties

  • Exact Mass: 210.08900
  • Monoisotopic Mass: 210.088581
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 1
  • Complexity: 214
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 46.7

Experimental Properties

  • Color/Form: Not determined
  • Density: 1.075
  • Melting Point: 66.0 to 70.0 deg-C
  • Boiling Point: 286.5°C at 760 mmHg
  • Flash Point: 127.099℃
  • Refractive Index: 1.501
  • PSA: 46.70000
  • LogP: 2.04730
  • Solubility: Not determined

4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane Security Information

4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Fluorochem
033893-1g
2-(Thiopheneboronic acid)pinacol ester
 193978-23-3 97%
1g
 ￡12.00 2022-02-28
Fluorochem
033893-10g
2-(Thiopheneboronic acid)pinacol ester
 193978-23-3 97%
10g
 ￡51.00 2022-02-28
Fluorochem
033893-25g
2-(Thiopheneboronic acid)pinacol ester
 193978-23-3 97%
25g
 ￡97.00 2022-02-28
Fluorochem
033893-100g
2-(Thiopheneboronic acid)pinacol ester
 193978-23-3 97%
100g
 ￡311.00 2022-02-28
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
T120116-1g
4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane
 193978-23-3 98%
1g
 ￥29.90 2023-09-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
T120116-5g
4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane
 193978-23-3 98%
5g
 ￥66.90 2023-09-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
T120116-25g
4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane
 193978-23-3 98%
25g
 ￥295.90 2023-09-01
Chemenu
CM133960-50g
4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane
 193978-23-3 0.95
50g
 $360 2021-08-05
Alichem
A449039491-100g
4,4,5,5-Tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane
 193978-23-3 95%
100g
 $223.45 2023-09-02
Alichem
A449039491-500g
4,4,5,5-Tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane
 193978-23-3 95%
500g
 $725.18 2023-09-02

4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane Production Method

4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane Related Literature

Related Categories

193978-23-3 (4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane) Related Products

Recommended suppliers
Shanghai Pearlk Chemicals Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinan Hanyu Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinan Hanyu Chemical Co.,Ltd.
Shenzhen Yaoyuan R&D Center Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shenzhen Yaoyuan R&D Center Co.,Ltd
Shandong Feiyang Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Feiyang Chemical Co., Ltd
Xiamen PinR Bio-tech Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Xiamen PinR Bio-tech Co., Ltd.