Cas no 19365-08-3 (3-Hydroxypiperidin-2-one)

3-Hydroxypiperidin-2-one is a heterocyclic organic compound featuring a hydroxyl group at the 3-position and a lactam moiety within a six-membered piperidine ring. This structure imparts versatility in synthetic applications, particularly as a building block in pharmaceutical and agrochemical research. The presence of both hydroxyl and lactam functionalities enables participation in diverse reactions, including nucleophilic substitutions and ring-opening transformations. Its stable yet reactive nature makes it valuable for constructing complex molecular frameworks, such as bioactive alkaloids or peptidomimetics. The compound’s well-defined stereochemistry further enhances its utility in enantioselective synthesis. Suitable for controlled modifications, it serves as a key intermediate in developing targeted therapeutic agents.

3-Hydroxypiperidin-2-one structure

Product Name:3-Hydroxypiperidin-2-one

CAS No:19365-08-3

MF:C₅H₉NO₂

MW:115.130461454391

MDL:MFCD00023163

CID:231614

PubChem ID:264990

Update Time:2025-05-27

3-Hydroxypiperidin-2-one Chemical and Physical Properties

Names and Identifiers

- 3-Hydroxypiperidin-2-one
- 2-Piperidinone,3-hydroxy-
- 3-Hydroxy-2-piperidone
- 3-Hydroxy-piperidin-2-one
- 2-Piperidinone,3-hydroxy
- 3-Hydroxy-2-piperidinone
- 3-hydroxypiperidin-2-on
- 3-hydroxypyperidin-2-one
- 2-Piperidinone, 3-hydroxy-
- NSC100722
- RYKLZUPYJFFNRR-UHFFFAOYSA-N
- BH551
- RW2893
- RP19187
- AB0023140
- ST2410734
- W4139
- SILVERMETHANESULFONATE
- FT-0650422
- 19365-08-3
- SCHEMBL2785455
- CS-W008630
- DTXSID50295242
- (3S)-3-Hydroxy-2-piperidinone
- SY110845
- SB23118
- EN300-126596
- MFCD00023163
- GS-3884
- NSC 100722
- SB41293
- A854115
- CHEMBL4535577
- NSC-100722
- J-502452
- (3R)-3-Hydroxy-2-piperidinone
- SB23117
- J-512627
- AKOS006274551
- DTXCID00246380
- DB-065826
- MDL： MFCD00023163
- Inchi： 1S/C5H9NO2/c7-4-2-1-3-6-5(4)8/h4,7H,1-3H2,(H,6,8)
- InChI Key： RYKLZUPYJFFNRR-UHFFFAOYSA-N
- SMILES： OC1C(NCCC1)=O

Computed Properties

Exact Mass: 115.06300
Monoisotopic Mass: 115.063
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Heavy Atom Count: 8
Rotatable Bond Count: 0
Complexity: 103
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: 5
XLogP3: -0.6
Topological Polar Surface Area: 49.3

Experimental Properties

Color/Form: No data avaiable
Density: 1.199
Melting Point: No data available
Boiling Point: 352.3°C at 760 mmHg
Flash Point: 166.8°C
Refractive Index: 1.497
PSA: 49.33000
LogP: -0.41390
Vapor Pressure: 0.0±1.8 mmHg at 25°C

3-Hydroxypiperidin-2-one Security Information

Signal Word：warning
Hazard Statement： H302-H315-H319-H332-H335
Warning Statement： P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care
Safety Instruction： H303+H313+H333
Storage Condition：Sealed in dry,2-8°C

3-Hydroxypiperidin-2-one Customs Data

HS CODE：2933790090
Customs Data：

China Customs Code:
2933790090

Overview:

2933790090 Other lactams. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:9.0% general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

3-Hydroxypiperidin-2-one Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.	H842152-250mg	3-Hydroxypiperidin-2-one	19365-08-3	98%	250mg	765.90	2021-05-17
TRC	H805330-50mg	3-Hydroxypiperidin-2-one	19365-08-3		50mg	$ 150.00	2023-04-15
TRC	H805330-100mg	3-Hydroxypiperidin-2-one	19365-08-3		100mg	$ 282.00	2023-04-15
TRC	H805330-250mg	3-Hydroxypiperidin-2-one	19365-08-3		250mg	$ 603.00	2023-04-15
TRC	H805330-500mg	3-Hydroxypiperidin-2-one	19365-08-3		500mg	$ 1154.00	2023-04-15
ChemScence	CS-W008630-100mg	3-Hydroxy-2-piperidinone	19365-08-3	>97.0%	100mg	$49.0	2022-04-27
ChemScence	CS-W008630-250mg	3-Hydroxy-2-piperidinone	19365-08-3	>97.0%	250mg	$74.0	2022-04-27
ChemScence	CS-W008630-1g	3-Hydroxy-2-piperidinone	19365-08-3	>97.0%	1g	$203.0	2022-04-27
ChemScence	CS-W008630-5g	3-Hydroxy-2-piperidinone	19365-08-3	>97.0%	5g	$710.0	2022-04-27
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	H191839-100mg	3-Hydroxypiperidin-2-one	19365-08-3	98%	100mg	￥197.90	2023-09-02

3-Hydroxypiperidin-2-one Production Method

3-Hydroxypiperidin-2-one Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:19365-08-3)3-hydroxypiperidin-2-one

Order Number:A854115

Stock Status:in Stock

Quantity:5g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 07:48

Price ($):284.0

Email:[email protected]

Product Official Link

3-Hydroxypiperidin-2-one Related Literature

1. Synthesis of (3R,6R)- and (3S,6R)-piperidinone PNA

Ask Püschl,Thomas Boesen,Tullia Tedeschi,Otto Dahl,Peter E. Nielsen J. Chem. Soc. Perkin Trans. 1 2001 2757
2. Chapter 11. Heterocyclic chemistry

R. J. Stoodley Annu. Rep. Prog. Chem. Sect. B: Org. Chem. 1967 64 375

Related Categories

Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Piperidines Piperidinones

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