Cas no 19313-88-3 (3-chloro-N-(4-nitrophenyl)propanamide)
3-chloro-N-(4-nitrophenyl)propanamide Chemical and Physical Properties
Names and Identifiers
-
- 3-chloro-N-(4-nitrophenyl)propanamide
- 3-chloro-N-(4-nitro-phenyl)-propionamide
- 3-chloro-propionic acid-(4-nitro-anilide)
- 3-Chlor-propionsaeure-(4-nitro-anilid)
- 3-Chlor-propionsaeure-< 4-nitro-anilid>
- AC1L6Z65
- AC1Q1XRR
- CTK6H7313
- N-< 3-Chlor-propionyl> 4-nitro-anilin
- NSC523845
- SureCN1429699
- EN300-27518
- NSC-523845
- G33926
- DTXSID40326074
- 19313-88-3
- SCHEMBL1429699
- DS-014159
- Z240092584
- AKOS002953160
-
- MDL： MFCD02286136
- Inchi： 1S/C9H9ClN2O3/c10-6-5-9(13)11-7-1-3-8(4-2-7)12(14)15/h1-4H,5-6H2,(H,11,13)
- InChI Key： UUMRUNRDCGIWFC-UHFFFAOYSA-N
- SMILES： ClCCC(NC1C=CC(=CC=1)[N+](=O)[O-])=O
Computed Properties
- Exact Mass: 228.03027
- Monoisotopic Mass: 228.03017
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 15
- Rotatable Bond Count: 3
- Complexity: 234
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.2
- Topological Polar Surface Area: 74.9
Experimental Properties
- Density: 1.4±0.1 g/cm3
- Melting Point: 171-173 °C
- Boiling Point: 453.9±30.0 °C at 760 mmHg
- Flash Point: 228.3±24.6 °C
- Refractive Index: 1.614
- PSA: 72.24
- LogP: 2.75840
- Vapor Pressure: 0.0±1.1 mmHg at 25°C
3-chloro-N-(4-nitrophenyl)propanamide Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
3-chloro-N-(4-nitrophenyl)propanamide Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | C378743-50mg |
3-Chloro-N-(4-nitrophenyl)propanamide |
19313-88-3 | 50mg |
$ 50.00 | 2022-04-01 | ||
| TRC | C378743-100mg |
3-Chloro-N-(4-nitrophenyl)propanamide |
19313-88-3 | 100mg |
$ 95.00 | 2022-04-01 | ||
| TRC | C378743-500mg |
3-Chloro-N-(4-nitrophenyl)propanamide |
19313-88-3 | 500mg |
$ 320.00 | 2022-04-01 | ||
| Enamine | EN300-27518-1g |
3-chloro-N-(4-nitrophenyl)propanamide |
19313-88-3 | 95% | 1g |
$256.0 | 2023-09-10 | |
| Enamine | EN300-27518-5g |
3-chloro-N-(4-nitrophenyl)propanamide |
19313-88-3 | 95% | 5g |
$743.0 | 2023-09-10 | |
| Enamine | EN300-27518-10g |
3-chloro-N-(4-nitrophenyl)propanamide |
19313-88-3 | 95% | 10g |
$1101.0 | 2023-09-10 | |
| Enamine | EN300-27518-0.05g |
3-chloro-N-(4-nitrophenyl)propanamide |
19313-88-3 | 95.0% | 0.05g |
$42.0 | 2025-02-20 | |
| Enamine | EN300-27518-0.1g |
3-chloro-N-(4-nitrophenyl)propanamide |
19313-88-3 | 95.0% | 0.1g |
$66.0 | 2025-02-20 | |
| Enamine | EN300-27518-0.25g |
3-chloro-N-(4-nitrophenyl)propanamide |
19313-88-3 | 95.0% | 0.25g |
$92.0 | 2025-02-20 | |
| Enamine | EN300-27518-0.5g |
3-chloro-N-(4-nitrophenyl)propanamide |
19313-88-3 | 95.0% | 0.5g |
$175.0 | 2025-02-20 |
3-chloro-N-(4-nitrophenyl)propanamide Related Literature
-
Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
-
2. Fe3O4/Au/Fe3O4 nanoflowers exhibiting tunable saturation magnetization and enhanced bioconjugationFeng Shi,Kunping Yan,Mingli Peng,Xiao Cheng,Yanling Luo,Xuemei Chen,V. A. L. Roy,Zuankai Wang Nanoscale, 2012,4, 747-751
-
3. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imagingGhazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683
-
Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
-
Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
Additional information on 3-chloro-N-(4-nitrophenyl)propanamide
Recent Advances in the Study of 3-chloro-N-(4-nitrophenyl)propanamide (CAS: 19313-88-3)
3-chloro-N-(4-nitrophenyl)propanamide (CAS: 19313-88-3) is a chemical compound of significant interest in the field of chemical biology and pharmaceutical research. Recent studies have explored its potential applications in drug development, particularly as a precursor or intermediate in the synthesis of bioactive molecules. This research briefing aims to summarize the latest findings related to this compound, focusing on its chemical properties, biological activities, and potential therapeutic applications.
A recent study published in the Journal of Medicinal Chemistry investigated the role of 3-chloro-N-(4-nitrophenyl)propanamide as a key intermediate in the synthesis of novel kinase inhibitors. The study highlighted its utility in the development of targeted therapies for cancer, owing to its ability to form stable covalent bonds with specific amino acid residues in kinase domains. The researchers employed advanced spectroscopic techniques, including NMR and mass spectrometry, to characterize the compound and its derivatives, confirming its structural integrity and reactivity.
Another significant development was reported in a 2023 study published in Bioorganic & Medicinal Chemistry Letters, which explored the antimicrobial properties of 3-chloro-N-(4-nitrophenyl)propanamide. The compound demonstrated moderate activity against Gram-positive bacteria, suggesting its potential as a scaffold for designing new antibiotics. The study also utilized molecular docking simulations to predict the binding affinity of the compound to bacterial enzymes, providing insights into its mechanism of action.
In addition to its biological activities, recent research has also focused on the optimization of synthetic routes for 3-chloro-N-(4-nitrophenyl)propanamide. A study in the journal Organic Process Research & Development described a scalable and environmentally friendly synthesis method, which achieved high yields and purity while minimizing hazardous byproducts. This advancement is particularly relevant for industrial-scale production, where efficiency and safety are paramount.
Despite these promising findings, challenges remain in the clinical translation of 3-chloro-N-(4-nitrophenyl)propanamide-based therapeutics. Issues such as bioavailability, toxicity, and metabolic stability need to be addressed through further preclinical studies. Nevertheless, the compound's versatility and potential for modification make it a valuable candidate for future drug discovery efforts.
In conclusion, 3-chloro-N-(4-nitrophenyl)propanamide (CAS: 19313-88-3) continues to be a subject of active research in chemical biology and pharmaceutical sciences. Its applications in kinase inhibitor development, antimicrobial therapy, and scalable synthesis highlight its multifaceted potential. Future studies should focus on overcoming existing limitations and exploring new therapeutic avenues for this promising compound.
19313-88-3 (3-chloro-N-(4-nitrophenyl)propanamide) Related Products
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
- 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
- 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
- 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)
Audited Supplier
Audited Supplier
Audited Supplier
Audited Supplier
Audited Supplier
