Cas no 19216-68-3 (6,7-dimethoxy-N~2~,N~2~-dimethylquinazoline-2,4-diamine)

6,7-Dimethoxy-N~2~,N~2~-dimethylquinazoline-2,4-diamine is a quinazoline derivative characterized by its dimethylamino and dimethoxy functional groups. This compound is of interest in medicinal chemistry due to its potential as a scaffold for kinase inhibitors or other biologically active molecules. The dimethoxy substitutions at the 6 and 7 positions enhance electron density, potentially improving binding affinity to target proteins. The dimethylamino group at the 2-position contributes to solubility and pharmacokinetic properties. Its well-defined structure makes it suitable for structure-activity relationship (SAR) studies. The compound is typically synthesized under controlled conditions to ensure high purity, making it valuable for research applications in drug discovery and development.
6,7-dimethoxy-N~2~,N~2~-dimethylquinazoline-2,4-diamine structure
19216-68-3 structure
Product Name:6,7-dimethoxy-N~2~,N~2~-dimethylquinazoline-2,4-diamine
CAS No:19216-68-3
MF:C12H17ClN4O2
MW:284.741981267929
CID:1385313
PubChem ID:6602978
Update Time:2025-06-27

6,7-dimethoxy-N~2~,N~2~-dimethylquinazoline-2,4-diamine Chemical and Physical Properties

Names and Identifiers

    • 6,7-dimethoxy-N~2~,N~2~-dimethylquinazoline-2,4-diamine
    • 6,7-dimethoxy-N,N-dimethyl-quinazoline-2,4-diamine
    • NSC-403405
    • 6,7-Dimethoxy-N2,N2-dimethyl-2,4-quinazolinediamine hydrochloride
    • Alfuzosin Impurity 1
    • SR-01000161952-1
    • Quinazoline, 4-amino-2-(dimethylamino)-6,7-dimethoxy-, monohydrochloride
    • UNII-83DP5NZ4FN
    • CHEMBL1382693
    • 2,4-Quinazolinediamine, 6,7-dimethoxy-N2,N2-dimethyl-, hydrochloride (1:1)
    • NSC403405
    • SR-01000161952
    • 2,4-Quinazolinediamine, 6,7-dimethoxy-N2,N2-dimethyl-, monohydrochloride
    • 19216-68-3
    • SMR000033893
    • 4-AMINO-6,7-DIMETHOXY-2-DIMETHYLAMINOQUINAZOLINE HYDROCHLORIDE
    • 83DP5NZ4FN
    • MLS000047893
    • 6,7-dimethoxy-2-N,2-N-dimethylquinazoline-2,4-diamine;hydrochloride
    • Inchi: 1S/C12H16N4O2.ClH/c1-16(2)12-14-8-6-10(18-4)9(17-3)5-7(8)11(13)15-12;/h5-6H,1-4H3,(H2,13,14,15);1H
    • InChI Key: ZPYIZKJUGLCUHO-UHFFFAOYSA-N
    • SMILES: Cl.O(C)C1C(=CC2C(=C(N)N=C(N=2)N(C)C)C=1)OC

Computed Properties

  • Exact Mass: 248.12748
  • Monoisotopic Mass: 248.127326
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 3
  • Complexity: 277
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.7
  • Topological Polar Surface Area: 73.5

Experimental Properties

  • Density: 1.252
  • Boiling Point: 437.4°C at 760 mmHg
  • Flash Point: 218.4°C
  • Refractive Index: 1.648
  • PSA: 73.5

6,7-dimethoxy-N~2~,N~2~-dimethylquinazoline-2,4-diamine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Biosynth
IA182629-10 mg
Alfuzosin EP Impurity F hydrochloride
19216-68-3
10mg
$280.00 2023-01-04
Biosynth
IA182629-25 mg
Alfuzosin EP Impurity F hydrochloride
19216-68-3
25mg
$500.00 2023-01-04
Biosynth
IA182629-50 mg
Alfuzosin EP Impurity F hydrochloride
19216-68-3
50mg
$700.00 2023-01-04
Biosynth
IA182629-100 mg
Alfuzosin EP Impurity F hydrochloride
19216-68-3
100MG
$1,000.00 2023-01-04
Biosynth
IA182629-250 mg
Alfuzosin EP Impurity F hydrochloride
19216-68-3
250MG
$1,625.00 2023-01-04

Additional information on 6,7-dimethoxy-N~2~,N~2~-dimethylquinazoline-2,4-diamine

6,7-Dimethoxy-N2,N2-Dimethylquinazoline-2,4-Diamine (CAS No. 19216-68-3)

The compound 6,7-Dimethoxy-N2,N2-Dimethylquinazoline-2,4-Diamine (CAS No. 19216-68-3) is a highly specialized organic molecule with significant potential in various fields of chemistry and materials science. This compound belongs to the class of quinazoline derivatives, which have been extensively studied due to their unique chemical properties and biological activities. The quinazoline backbone serves as a versatile platform for the design of novel compounds with tailored functionalities.

The structure of 6,7-Dimethoxy-N2,N2-Dimethylquinazoline-2,4-Diamine features a quinazoline ring system with methoxy groups at positions 6 and 7 and dimethylamino groups at position 4. This substitution pattern imparts unique electronic and steric properties to the molecule, making it an attractive candidate for applications in drug discovery and advanced materials development.

Recent studies have highlighted the importance of quinazoline derivatives in medicinal chemistry, particularly as potential leads for anti-cancer agents. The dimethoxy substitution at positions 6 and 7 enhances the molecule's solubility and bioavailability, which are critical factors for drug candidates. Additionally, the dimethylamino groups at position 4 contribute to hydrogen bonding capabilities, further enhancing the molecule's interaction with biological targets.

In terms of synthesis, 6,7-Dimethoxy-N2,N2-Dimethylquinazoline-2,4-Diamine can be prepared through a multi-step process involving nucleophilic aromatic substitution and subsequent functionalization. Researchers have optimized these synthetic routes to improve yield and purity, making this compound more accessible for large-scale applications.

The application of this compound extends beyond pharmacology into areas such as optoelectronics and sensors. The quinazoline core exhibits strong fluorescence properties under UV light, which can be exploited in the development of advanced materials for light-emitting diodes (LEDs) and biosensors.

Recent advancements in computational chemistry have enabled detailed studies of the electronic structure of 6,7-Dimethoxy-N2,N2-Dimethylquinazoline-2,4-Diamine, providing insights into its reactivity and stability under various conditions. These studies are crucial for understanding its behavior in different chemical environments and optimizing its performance in practical applications.

In conclusion, 6,7-Dimethoxy-N2,N2-Dimethylquinazoline-2,4-Diamine (CAS No. 19216-68-3) is a versatile compound with promising potential across multiple disciplines. Its unique chemical structure and functional groups make it an invaluable tool for researchers seeking innovative solutions in drug discovery and materials science.

Recommended suppliers
Jinan Hanyu Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinan Hanyu Chemical Co.,Ltd.
Nanjing jingzhu bio-technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Nanjing jingzhu bio-technology Co., Ltd.
Hebei Liye chemical Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hebei Liye chemical Co.,Ltd
Xiamen PinR Bio-tech Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Xiamen PinR Bio-tech Co., Ltd.
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.