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• 5. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
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Comprehensive Guide to 2,4-Diiodo-1H-imidazole (CAS No. 19198-80-2): Properties, Applications, and Research Insights

2,4-Diiodo-1H-imidazole (CAS No. 19198-80-2) is a halogenated heterocyclic compound that has garnered significant attention in pharmaceutical and materials science research. This iodo-substituted imidazole derivative is characterized by its unique molecular structure, where two iodine atoms are strategically positioned at the 2 and 4 positions of the imidazole ring. Such modifications enhance its reactivity and make it a valuable intermediate in organic synthesis. Researchers frequently search for "2,4-Diiodo-1H-imidazole synthesis" or "CAS 19198-80-2 applications," reflecting its growing importance in specialized chemical workflows.

The compound's physicochemical properties are critical for its applications. With a molecular formula of C₃H₂I₂N₂, it exhibits high stability under controlled conditions. Its iodine-rich structure contributes to its utility in cross-coupling reactions, a topic often queried as "imidazole derivatives in catalysis." Recent studies highlight its role in constructing complex molecules, particularly in medicinal chemistry, where researchers explore "iodoimidazoles as bioactive scaffolds."

In the context of drug discovery, 2,4-Diiodo-1H-imidazole serves as a precursor for designing kinase inhibitors and antimicrobial agents. Searches like "imidazole-based drug candidates 2024" align with industry trends toward heterocyclic compounds. Its ability to participate in palladium-catalyzed reactions (e.g., Sonogashira or Suzuki couplings) is frequently discussed in forums focusing on "advanced synthetic methodologies."

Beyond pharmaceuticals, this compound finds niche applications in material science. Its halogen bonds enable the development of supramolecular architectures, a hot topic in "smart materials research." Users often inquire about "iodoimidazoles in optoelectronics," reflecting interest in its potential for organic semiconductors or light-emitting diodes (LEDs).

Handling 2,4-Diiodo-1H-imidazole requires adherence to standard laboratory safety protocols. While not classified as hazardous under normal conditions, proper storage away from light and moisture is essential—details often sought under "CAS 19198-80-2 storage guidelines." Analytical techniques like NMR spectroscopy and HPLC purity testing are commonly used for characterization, as noted in queries such as "how to analyze diiodoimidazole purity."

Environmental and regulatory considerations are also trending topics. The compound's biodegradability and green chemistry alternatives are explored under searches like "sustainable halogenated compound synthesis." Regulatory databases (e.g., REACH) provide compliance data, addressing queries such as "19198-80-2 regulatory status."

In summary, 2,4-Diiodo-1H-imidazole (CAS No. 19198-80-2) bridges multiple scientific disciplines. Its versatility in organic synthesis, combined with emerging applications in life sciences and advanced materials, ensures its relevance in contemporary research. For those investigating "imidazole chemistry trends" or "high-value chemical intermediates," this compound offers a compelling case study.

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