Cas no 191725-60-7 (2-(2,6-Dichlorophenyl)propanal)

2-(2,6-Dichlorophenyl)propanal is a chlorinated aromatic aldehyde with a molecular formula of C9H8Cl2O. This compound features a propanal side chain attached to a 2,6-dichlorophenyl group, making it a versatile intermediate in organic synthesis. Its dichlorinated aromatic ring enhances stability and reactivity, particularly in electrophilic substitution reactions. The aldehyde functional group allows for further derivatization, enabling applications in pharmaceuticals, agrochemicals, and specialty chemicals. The compound’s structural rigidity and electron-withdrawing chlorine substituents contribute to its utility in fine chemical synthesis. It is commonly used in the preparation of active pharmaceutical ingredients (APIs) and other high-value intermediates requiring precise functional group manipulation.
2-(2,6-Dichlorophenyl)propanal structure
191725-60-7 structure
Product Name:2-(2,6-Dichlorophenyl)propanal
CAS No:191725-60-7
MF:C9H8Cl2O
MW:203.065220832825
MDL:MFCD23098639
CID:2104212
PubChem ID:21835210
Update Time:2025-06-10

2-(2,6-Dichlorophenyl)propanal Chemical and Physical Properties

Names and Identifiers

    • 2-(2,6-dichlorophenyl)propanal
    • 2,6-Dichlorophenylpropanal
    • BDCUJINXZXJKKK-UHFFFAOYSA-N
    • 2-(2,6-Dichlorophenyl)propanal
    • MDL: MFCD23098639
    • Inchi: 1S/C9H8Cl2O/c1-6(5-12)9-7(10)3-2-4-8(9)11/h2-6H,1H3
    • InChI Key: BDCUJINXZXJKKK-UHFFFAOYSA-N
    • SMILES: ClC1C=CC=C(C=1C(C=O)C)Cl

Computed Properties

  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 151
  • Topological Polar Surface Area: 17.1

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Additional information on 2-(2,6-Dichlorophenyl)propanal

Comprehensive Overview of 2-(2,6-Dichlorophenyl)propanal (CAS No. 191725-60-7): Properties, Applications, and Industry Insights

2-(2,6-Dichlorophenyl)propanal (CAS No. 191725-60-7) is a specialized organic compound featuring a dichlorophenyl group attached to a propanal backbone. This structure grants it unique chemical properties, making it valuable in synthetic chemistry, particularly in the development of pharmaceutical intermediates and agrochemicals. Researchers and manufacturers frequently seek this compound due to its role in constructing complex molecules, such as nonsteroidal anti-inflammatory drugs (NSAIDs) analogs and flavor/fragrance precursors.

The growing demand for high-purity intermediates in drug discovery has spotlighted compounds like 2-(2,6-Dichlorophenyl)propanal. Its electrophilic aldehyde group allows for versatile reactions, including condensation and reduction, which are critical in asymmetric synthesis. Recent studies highlight its utility in green chemistry applications, aligning with the industry’s shift toward sustainable practices. For instance, its use in catalyzed cross-coupling reactions reduces waste generation, addressing environmental concerns.

Analytical techniques such as HPLC, GC-MS, and NMR spectroscopy are essential for verifying the purity of CAS No. 191725-60-7. Impurities in intermediates can significantly impact downstream processes, a topic frequently queried in pharmaceutical forums. Stability studies under varying temperatures and pH levels are also crucial, as degradation products may affect efficacy in final formulations.

In the flavor and fragrance industry, 2-(2,6-Dichlorophenyl)propanal serves as a precursor for aryl-substituted aldehydes, which contribute to unique sensory profiles. This aligns with consumer trends favoring natural-identical compounds over synthetic additives. Regulatory compliance, such as REACH and FDA guidelines, governs its use, ensuring safety in end products—a recurring theme in supplier audits and material safety data sheets (MSDS).

Supply chain transparency is another hot topic. Manufacturers of 191725-60-7 must adhere to Good Manufacturing Practices (GMP) to meet global standards. Searches for "reliable CAS 191725-60-7 suppliers" often emphasize certifications like ISO 9001 and batch-specific Certificates of Analysis (CoA). Additionally, innovations in packaging technologies (e.g., nitrogen-sealed containers) extend shelf life, reducing procurement risks.

Future research may explore 2-(2,6-Dichlorophenyl)propanal’s potential in biocatalysis or nanomaterial synthesis, areas gaining traction in academic literature. Its adaptability positions it as a candidate for high-value niche applications, from electronic chemicals to specialty polymers. As industries prioritize custom synthesis solutions, this compound’s role is poised to expand, driven by interdisciplinary collaboration and patent-protected methodologies.

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