• 1. Evolution of hierarchical porous structures in supramolecular guest–host hydrogels?
  Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
• 2. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 3. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
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• 4. Examination of ammonia–poly(pyrrole) interactions by piezoelectric and conductivity measurements
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• 5. Fe3O4 nanoparticle chains with N-doped carbon coating: magnetotactic bacteria assisted synthesis and high-rate lithium storage?
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives Indolines

Comprehensive Overview of 3,3-Dimethyl-1,3-dihydro-indole-2-thione (CAS No. 19155-25-0): Properties, Applications, and Industry Insights

3,3-Dimethyl-1,3-dihydro-indole-2-thione (CAS No. 19155-25-0) is a sulfur-containing heterocyclic compound that has garnered significant attention in pharmaceutical and material science research. This indole-2-thione derivative is characterized by its unique molecular structure, which combines a dimethyl-substituted indole core with a thione functional group. The compound's structural features contribute to its diverse reactivity and potential applications, making it a subject of ongoing scientific exploration.

In recent years, the demand for specialty chemicals like 3,3-Dimethyl-1,3-dihydro-indole-2-thione has increased due to their utility in drug discovery and organic synthesis. Researchers are particularly interested in its role as a building block for more complex molecules, especially in the development of heterocyclic compounds with potential biological activity. The compound's CAS number 19155-25-0 serves as a crucial identifier in chemical databases and regulatory documentation, ensuring precise communication across scientific and industrial sectors.

The synthesis of 3,3-Dimethyl-1,3-dihydro-indole-2-thione typically involves the reaction of 3,3-dimethylindoline with sulfurizing agents, yielding the thione derivative with good purity. This sulfur-containing compound exhibits distinct spectroscopic properties, including characteristic UV-Vis absorption and NMR signals, which facilitate its identification and quality control. Analytical techniques such as HPLC and mass spectrometry are commonly employed to verify the compound's identity and assess its stability under various conditions.

From an applications perspective, 3,3-Dimethyl-1,3-dihydro-indole-2-thione has shown promise in multiple domains. In medicinal chemistry, it serves as a precursor for compounds being investigated for their potential pharmacological properties. The indole-thione scaffold is known to interact with various biological targets, sparking interest in its structure-activity relationships. Additionally, materials scientists are exploring its use in organic electronics due to its electron-rich structure and potential charge transport properties.

The growing interest in sustainable chemistry has also impacted research on CAS 19155-25-0. Scientists are investigating green synthesis methods for this compound, focusing on catalyst optimization and waste reduction. These efforts align with broader industry trends toward environmentally friendly production of specialty chemicals. Furthermore, the compound's stability profile and storage requirements are frequently discussed topics among researchers and manufacturers alike.

Quality control remains paramount when working with 3,3-Dimethyl-1,3-dihydro-indole-2-thione. Reputable suppliers provide comprehensive analytical certificates that detail parameters such as purity percentage, melting point, and solubility characteristics. These specifications are critical for researchers who require consistent performance in their experiments. The compound's shelf life and recommended storage conditions are also important considerations for long-term research projects.

In the context of intellectual property, several patents mention 3,3-Dimethyl-1,3-dihydro-indole-2-thione as an intermediate in various synthetic routes. This highlights its commercial importance in pharmaceutical development and other specialty chemical applications. The compound's regulatory status varies by region, and proper safety documentation should always be consulted before handling.

Looking ahead, the scientific community continues to explore novel applications for 3,3-Dimethyl-1,3-dihydro-indole-2-thione. Its versatility as a chemical intermediate and potential biological activity make it a valuable subject for ongoing research. As analytical techniques advance and computational chemistry methods improve, researchers gain deeper insights into the compound's properties and potential uses across multiple disciplines.

For those seeking technical data on CAS 19155-25-0, numerous scientific databases and chemical catalogs provide detailed information. The compound's molecular formula, exact mass, and spectral data are readily available to support research efforts. Additionally, structure-activity relationship studies continue to reveal how modifications to the indole-thione core might enhance specific properties for targeted applications.

The market for fine chemicals like 3,3-Dimethyl-1,3-dihydro-indole-2-thione is influenced by trends in pharmaceutical R&D and advanced materials development. As these industries evolve, the demand for high-quality chemical intermediates with well-characterized properties is expected to grow. This underscores the importance of maintaining rigorous quality standards throughout the compound's production and distribution chain.

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