Cas no 190710-79-3 (N-Desmethyl Topotecan)
N-Desmethyl Topotecan structure
Product Name:N-Desmethyl Topotecan
CAS No:190710-79-3
MF:C22H21N3O5
MW:407.419245481491
CID:139264
PubChem ID:9931216
Update Time:2025-04-19
N-Desmethyl Topotecan Chemical and Physical Properties
Names and Identifiers
-
- 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4,9-dihydroxy-10-[(methylamino)methyl]-, (4S)-
- 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4,9-dihydroxy-10-[(m...
- N-Desmethyl Topotecan
- (4S)-4-Ethyl-4,9-dihydroxy-10-[(methylamino)methyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- Topotecan N-Desmethyl Impurity
- Topotecan N-DesMethyl Metabolite
- N-Desmethyl Topotecan Hydrochloride Labeled d3
- (S)-10-[(Methylamino) methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano [3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- SK&F-105992
- N-Desmethyltopotecan
- AKOS015914524
- (19S)-19-ethyl-7,19-dihydroxy-8-(methylaminomethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
- Q27252419
- SCHEMBL14009660
- 190710-79-3
- 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-10-((methylamino)methyl)-, (4S)-
- 1H911D604G
- 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-10-[(methylamino)methyl]-, (4S)-
- DTXSID40433015
- (S)-4-Ethyl-4,9-dihydroxy-10-((methylamino)methyl)-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione
- 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4,9-dihydroxy-10-[(methylamino)methyl]-,(4S)-
- UNII-1H911D604G
- J-012309
- (4S)-4-Ethyl-4,9-dihydroxy-10-[(methylamino)methyl]-1H-pyrano[3?,4?:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- DTXCID80383843
-
- Inchi： 1S/C22H21N3O5/c1-3-22(29)15-7-17-19-11(9-25(17)20(27)14(15)10-30-21(22)28)6-12-13(8-23-2)18(26)5-4-16(12)24-19/h4-7,23,26,29H,3,8-10H2,1-2H3/t22-/m0/s1
- InChI Key： ZWUJOGCYOWLZFL-QFIPXVFZSA-N
- SMILES： O1C([C@](CC)(C2C=C3C4C(=CC5C(=C(C=CC=5N=4)O)CNC)CN3C(C=2C1)=O)O)=O
Computed Properties
- Exact Mass: 407.14800
- Monoisotopic Mass: 407.14812078g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 7
- Heavy Atom Count: 30
- Rotatable Bond Count: 3
- Complexity: 839
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.6
- Topological Polar Surface Area: 112?2
Experimental Properties
- Density: 1.5±0.1 g/cm3
- Melting Point: Not available
- Boiling Point: 815.5±65.0 °C at 760 mmHg
- Flash Point: 447.0±34.3 °C
- Refractive Index: 1.744
- PSA: 113.68000
- LogP: 1.89550
- Vapor Pressure: 0.0±3.1 mmHg at 25°C
N-Desmethyl Topotecan Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
-
Warning Statement：
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
N-Desmethyl Topotecan Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | D294400-1mg |
N-Desmethyl Topotecan |
190710-79-3 | 1mg |
$ 222.00 | 2023-09-08 | ||
| TRC | D294400-5mg |
N-Desmethyl Topotecan |
190710-79-3 | 5mg |
$ 930.00 | 2023-09-08 | ||
| TRC | D294400-10mg |
N-Desmethyl Topotecan |
190710-79-3 | 10mg |
$ 1681.00 | 2023-09-08 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-212194-1 mg |
N-Desmethyl Topotecan, |
190710-79-3 | 1mg |
￥2,708.00 | 2023-07-11 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-212194A-5 mg |
N-Desmethyl Topotecan, |
190710-79-3 | 5mg |
￥9,326.00 | 2023-07-11 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-212194-1mg |
N-Desmethyl Topotecan, |
190710-79-3 | 1mg |
￥2708.00 | 2023-09-05 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-212194A-5mg |
N-Desmethyl Topotecan, |
190710-79-3 | 5mg |
￥9326.00 | 2023-09-05 | ||
| A2B Chem LLC | AB12230-1mg |
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-10-[(methylamino)methyl]-, (4S)- |
190710-79-3 | 1mg |
$336.00 | 2024-04-20 | ||
| A2B Chem LLC | AB12230-5mg |
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-10-[(methylamino)methyl]-, (4S)- |
190710-79-3 | 5mg |
$1024.00 | 2024-04-20 | ||
| A2B Chem LLC | AB12230-10mg |
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-10-[(methylamino)methyl]-, (4S)- |
190710-79-3 | 10mg |
$1753.00 | 2024-04-20 |
N-Desmethyl Topotecan Related Literature
-
Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
-
Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
-
Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
-
Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
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