Cas no 19064-65-4 (3-Methoxypyridazine)

3-Methoxypyridazine structure
3-Methoxypyridazine structure
Product Name:3-Methoxypyridazine
CAS No:19064-65-4
MF:C5H6N2O
MW:110.11394071579
MDL:MFCD00234098
CID:123334
PubChem ID:87561370
Update Time:2025-07-23

3-Methoxypyridazine Chemical and Physical Properties

Names and Identifiers

    • 3-Methoxypyridazine
    • Pyridazine, 3-methoxy-
    • 3-METHOXYPYRADIAZINE
    • 3-Methoxy-pyridazin
    • 3-methoxy-pyridazine
    • methoxypyridazine
    • pyridazine,3-methoxy
    • 3-MethoxypyridaziIne
    • 3-Methoxy-1,2-diazine
    • DTXSID60303423
    • A880403
    • CS-W021957
    • ASFHDLDAWYTMJS-UHFFFAOYSA-N
    • AB05130
    • Pyridazine,3-methoxy-
    • FT-0646976
    • methoxydiazine
    • 19064-65-4
    • MFCD00234098
    • J-512801
    • M2078
    • SY047082
    • AC-25158
    • SCHEMBL910326
    • AKOS006280507
    • GS-4369
    • DTXCID90254555
    • DB-008318
    • MDL: MFCD00234098
    • Inchi: 1S/C5H6N2O/c1-8-5-3-2-4-6-7-5/h2-4H,1H3
    • InChI Key: ASFHDLDAWYTMJS-UHFFFAOYSA-N
    • SMILES: O(C)C1=CC=CN=N1

Computed Properties

  • Exact Mass: 110.04800
  • Monoisotopic Mass: 110.048012819g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 8
  • Rotatable Bond Count: 1
  • Complexity: 67.4
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 35?2
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing

Experimental Properties

  • Density: 1.102
  • Boiling Point: 87°C/13mmHg(lit.)
  • Flash Point: 89 oC
  • Refractive Index: 1.495
  • PSA: 35.01000
  • LogP: 0.48520
  • λmax: 265(H2O)(lit.)

3-Methoxypyridazine Security Information

3-Methoxypyridazine Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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3-Methoxypyridazine Related Literature

  • 1. Heterocyclic imines and amines. Part XVII. Confirmation of the structures of two aminopyridazinones
    Subhi Alazawe,John A. Elvidge J. Chem. Soc. Perkin Trans. 1 1974 696
  • 2. Nucleophilic displacement reactions of 3,6-dichloropyridazine 1-oxide with sulphur nucleophiles
    Michihiko Ochiai,Taiiti Okada,Akira Morimoto,Kenji Kawakita J. Chem. Soc. Perkin Trans. 1 1976 1988
  • 3. 247. The electronic spectra of N-heteroaromatic systems. Part III. The π→π transitions of the monocyclic hydroxy-azines
  • 4. Kinetics of reactions in heterocycles. Part V. Replacement of the methylsulphinyl and methylthio-groups in substituted six-membered nitrogen heterocycles by methoxide ion.
    G. B. Barlin,W. V. Brown J. Chem. Soc. B 1968 1435
  • 5. Pyridazines. Part III. Reaction of di- and tri-chlorodialkylaminopyridazines with nucleophiles
    R. S. Fenton,J. K. Landquist,S. E. Meek J. Chem. Soc. Perkin Trans. 1 1972 2323

Additional information on 3-Methoxypyridazine

Introduction to 3-Methoxypyridazine (CAS No. 19064-65-4)

3-Methoxypyridazine, a compound with the chemical formula C?H?N?O, is a significant molecule in the field of pharmaceutical chemistry and bioorganic synthesis. Its CAS number, 19064-65-4, uniquely identifies it in scientific literature and databases, facilitating precise referencing and research. This heterocyclic aromatic compound features a pyridazine core substituted with a methoxy group, which imparts unique electronic and steric properties essential for its applications in drug development and material science.

The structural integrity of 3-Methoxypyridazine is characterized by a six-membered ring containing two nitrogen atoms and one oxygen atom. The methoxy group (-OCH?) attached to the pyridazine ring enhances its reactivity, making it a versatile intermediate in organic synthesis. This compound has garnered attention due to its potential in developing novel therapeutic agents, particularly in the treatment of neurological disorders and infectious diseases.

Recent advancements in medicinal chemistry have highlighted the significance of 3-Methoxypyridazine as a pharmacophore. Its ability to interact with biological targets such as enzymes and receptors has been exploited to design molecules with enhanced binding affinity and selectivity. For instance, studies have demonstrated its role in modulating neurotransmitter pathways, making it a promising candidate for further investigation in neuropharmacology.

In the realm of synthetic organic chemistry, 3-Methoxypyridazine serves as a key building block for constructing more complex molecules. The methoxy group provides a site for further functionalization, allowing chemists to tailor the compound's properties for specific applications. Researchers have leveraged this flexibility to develop novel derivatives with improved pharmacokinetic profiles and reduced side effects.

The compound's electronic properties, influenced by the presence of nitrogen and oxygen heteroatoms, make it an attractive candidate for materials science applications. For example, it has been explored as a component in organic semiconductors and light-emitting diodes (OLEDs) due to its ability to absorb and emit light efficiently. These applications underscore the broad utility of 3-Methoxypyridazine beyond traditional pharmaceuticals.

Current research efforts are focused on optimizing synthetic routes to produce 3-Methoxypyridazine with higher yields and purity. Advances in catalytic methods have enabled more efficient transformations, reducing the environmental impact of its production. Additionally, green chemistry principles are being integrated into its synthesis to minimize waste and hazardous byproducts.

The pharmacological potential of 3-Methoxypyridazine has been further explored through computational modeling and high-throughput screening. These approaches have identified novel analogs with enhanced biological activity, paving the way for new drug candidates. Collaborative efforts between academic institutions and pharmaceutical companies are accelerating the translation of these findings into clinical applications.

The safety profile of 3-Methoxypyridazine is another critical area of study. Extensive toxicological assessments have been conducted to evaluate its potential health risks and environmental impact. These studies ensure that its use in research and industrial applications is conducted responsibly, adhering to regulatory guidelines.

Future directions in the study of 3-Methoxypyridazine include exploring its role in combinatorial therapy regimens. By pairing it with other bioactive compounds, researchers aim to develop synergistic treatments that are more effective than single-agent therapies. This approach holds promise for addressing complex diseases that require multifaceted interventions.

The integration of artificial intelligence (AI) into drug discovery has also revolutionized the study of 3-Methoxypyridazine. Machine learning algorithms can predict molecular properties and optimize synthetic pathways, significantly speeding up the development process. This technological synergy is transforming how new drugs are designed and validated.

In conclusion, 3-Methoxypyridazine (CAS No. 19064-65-4) is a multifaceted compound with substantial potential in pharmaceuticals, materials science, and synthetic chemistry. Its unique structural features and reactivity make it a valuable tool for researchers seeking to develop innovative solutions to global health challenges. As scientific understanding continues to evolve, the applications of this compound are expected to expand further, reinforcing its importance in modern chemistry.

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