Cas no 19040-67-6 (7,8-Dihydroxy-4-propyl-2H-chromen-2-one)

7,8-Dihydroxy-4-propyl-2H-chromen-2-one is a synthetic coumarin derivative characterized by its hydroxylated aromatic ring and propyl substituent at the 4-position. This compound exhibits notable reactivity due to the presence of two adjacent phenolic hydroxyl groups, which enhance its chelating and antioxidant properties. Its structural features make it a valuable intermediate in organic synthesis, particularly for developing pharmacologically active molecules or functional materials. The propyl chain contributes to improved lipophilicity, potentially influencing bioavailability in biological systems. Analytical applications may include its use as a reference standard or probe in studies involving redox processes. Careful handling is recommended due to the potential sensitivity of the catechol moiety to oxidation.

7,8-Dihydroxy-4-propyl-2H-chromen-2-one structure

19040-67-6 structure

Product Name:7,8-Dihydroxy-4-propyl-2H-chromen-2-one

CAS No:19040-67-6

MF:C₁₂H₁₂O₄

MW:220.221283912659

MDL:MFCD08705698

CID:123326

PubChem ID:11447325

Update Time:2025-05-24

7,8-Dihydroxy-4-propyl-2H-chromen-2-one Chemical and Physical Properties

Names and Identifiers

- 2H-1-Benzopyran-2-one,7,8-dihydroxy-4-propyl-
- 7,8-DIHYDROXY-4-PROPYL COUMARIN
- 7,8-Dihydroxy-4-propyl-2H-chromen-2-one
- 7,8-dihydroxy-4-propylchromen-2-one
- 7,8-dihydroxy-4-propyl-coumarin
- 7,8-Dihydroxy-4-propyl-cumarin
- BB_NC-1806
- 2H-1-Benzopyran-2-one, 7,8-dihydroxy-4-propyl-
- 19040-67-6
- FT-0751045
- SCHEMBL15295521
- AKOS004938591
- DTXSID10466158
- MFCD08705698
- VS-10249
- EN300-186384
- CS-0297251
- 7,8-Dihydroxy-4-propylcoumarin
- MDL： MFCD08705698
- Inchi： 1S/C12H12O4/c1-2-3-7-6-10(14)16-12-8(7)4-5-9(13)11(12)15/h4-6,13,15H,2-3H2,1H3
- InChI Key： PHPUSFBIYOLWBJ-UHFFFAOYSA-N
- SMILES： O1C(C=C(C2C=CC(=C(C1=2)O)O)CCC)=O

Computed Properties

Exact Mass: 220.07400
Monoisotopic Mass: 220.07355886g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Heavy Atom Count: 16
Rotatable Bond Count: 2
Complexity: 310
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 2.1
Topological Polar Surface Area: 66.8?2

Experimental Properties

Color/Form: NA
Density: 1.3±0.1 g/cm3
Melting Point: Not available
Boiling Point: 429.2±45.0 °C at 760 mmHg
Flash Point: 169.6±23.2 °C
Refractive Index: 1.609
PSA: 70.67000
LogP: 2.15670

7,8-Dihydroxy-4-propyl-2H-chromen-2-one Security Information

Signal Word：warning
Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Warning Statement： P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care
Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Storage Condition：Storage at -4 ℃ (6-12weeks), long storage period at -20 ℃ (1-2years), transport at 0 ℃
HazardClass：IRRITANT

7,8-Dihydroxy-4-propyl-2H-chromen-2-one Customs Data

HS CODE：2932209090
Customs Data：

China Customs Code:
2932209090

Overview:

2932209090. Other lactones. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to

Summary:

2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

7,8-Dihydroxy-4-propyl-2H-chromen-2-one Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
TRC	D267820-250mg	7,8-Dihydroxy-4-propyl-2H-chromen-2-one	19040-67-6		250mg	$ 185.00	2022-06-05
TRC	D267820-500mg	7,8-Dihydroxy-4-propyl-2H-chromen-2-one	19040-67-6		500mg	$ 300.00	2022-06-05
TRC	D267820-1000mg	7,8-Dihydroxy-4-propyl-2H-chromen-2-one	19040-67-6		1g	$ 480.00	2022-06-05
Chemenu	CM512855-1g	7,8-Dihydroxy-4-propyl-2H-chromen-2-one	19040-67-6	95%	1g	$176	2022-06-12
abcr	AB409310-500 mg	7,8-Dihydroxy-4-propyl-2H-chromen-2-one	19040-67-6		500MG	€195.40	2023-02-20
abcr	AB409310-1 g	7,8-Dihydroxy-4-propyl-2H-chromen-2-one	19040-67-6		1g	€239.00	2023-06-17
abcr	AB409310-5 g	7,8-Dihydroxy-4-propyl-2H-chromen-2-one	19040-67-6		5g	€656.50	2023-06-17
Ambeed	A564875-1g	7,8-Dihydroxy-4-propyl-2H-chromen-2-one	19040-67-6	95+%	1g	$178.0	2024-07-28
A2B Chem LLC	AB11963-500mg	7,8-Dihydroxy-4-propyl-2h-chromen-2-one	19040-67-6	>95%	500mg	$412.00	2024-04-20
A2B Chem LLC	AB11963-1g	7,8-Dihydroxy-4-propyl-2h-chromen-2-one	19040-67-6	>95%	1g	$439.00	2024-04-20

7,8-Dihydroxy-4-propyl-2H-chromen-2-one Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:19040-67-6)7,8-Dihydroxy-4-propyl-2H-chromen-2-one

Order Number:A1145648

Stock Status:in Stock

Quantity:1g

Purity:99%

Pricing Information Last Updated:Thursday, 29 August 2024 23:02

Price ($):160.0

Email:[email protected]

Product Official Link

7,8-Dihydroxy-4-propyl-2H-chromen-2-one Related Literature

1. Evolution of hierarchical porous structures in supramolecular guest–host hydrogels?

Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
2. Enabling stable MnO2 matrix for aqueous zinc-ion battery cathodes?

Yiding Jiao,Liqun Kang,Jasper Berry-Gair,Kit McColl,Jianwei Li,Haobo Dong,Hao Jiang,Ryan Wang,Furio Corà,Dan J. L. Brett,Ivan P. Parkin J. Mater. Chem. A, 2020,8, 22075-22082
3. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field

XuxinCheng,XiaomingChen,PengyuanFan
4. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?

Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
5. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?

Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789

Related Categories

Additional information on 7,8-Dihydroxy-4-propyl-2H-chromen-2-one

Exploring the Properties and Applications of 7,8-Dihydroxy-4-propyl-2H-chromen-2-one (CAS No. 19040-67-6)

7,8-Dihydroxy-4-propyl-2H-chromen-2-one, with the CAS number 19040-67-6, is a bioactive coumarin derivative that has garnered significant attention in pharmaceutical and cosmetic research. This compound belongs to the chromen-2-one family, characterized by its unique dihydroxy and propyl substitutions, which contribute to its antioxidant and anti-inflammatory properties. Researchers are increasingly exploring its potential in skincare formulations, particularly for its ability to neutralize free radicals and combat oxidative stress—a hot topic in anti-aging and dermatology.

In recent years, the demand for natural and synthetic antioxidants like 7,8-Dihydroxy-4-propyl-2H-chromen-2-one has surged, driven by consumer interest in "clean beauty" and sustainable ingredients. Searches for "coumarin derivatives for skin health" or "natural antioxidants in cosmetics" reflect this trend. The compound's CAS 19040-67-6 is often referenced in patent filings for formulations targeting hyperpigmentation and UV-induced damage, aligning with the growing market for sun care and brightening products.

From a biochemical perspective, the dihydroxy groups at positions 7 and 8 enhance the molecule's metal-chelating capacity, making it a candidate for studying neurodegenerative diseases linked to oxidative stress. This ties into popular queries such as "neuroprotective coumarins" or "antioxidants for brain health." Additionally, the propyl side chain improves lipid solubility, a critical factor for bioavailability in drug delivery systems—a key focus area in pharmaceutical R&D.

The synthesis of 7,8-Dihydroxy-4-propyl-2H-chromen-2-one typically involves Pechmann condensation or hydroxylation protocols, topics frequently searched by chemistry students and professionals. Its structural similarity to flavonoids also positions it as a subject in comparative studies on "plant-derived bioactive compounds," another trending research theme. Analytical techniques like HPLC and NMR are essential for verifying its purity, addressing common questions about "how to identify coumarin derivatives."

Beyond therapeutics, this compound's fluorescence properties have sparked interest in material science, particularly for developing sensors. Searches for "chromen-2-one applications in biosensors" highlight this niche. Regulatory-wise, CAS 19040-67-6 is not classified as hazardous, allowing broader experimental and commercial exploration. However, researchers must adhere to ethical guidelines, especially when investigating its effects on biological systems—an aspect emphasized in peer-reviewed literature.

In conclusion, 7,8-Dihydroxy-4-propyl-2H-chromen-2-one (19040-67-6) exemplifies the intersection of chemistry, medicine, and cosmetics. Its multifaceted applications respond to contemporary demands for multifunctional ingredients, while ongoing studies continue to uncover new potentials. For those exploring "innovative coumarin uses" or "next-gen antioxidant agents," this compound remains a compelling case study.

19040-67-6 (7,8-Dihydroxy-4-propyl-2H-chromen-2-one) Related Products

Recommended suppliers