Cas no 190271-85-3 (5-(bromomethyl)pyrrolidin-2-one)

5-(Bromomethyl)pyrrolidin-2-one is a versatile brominated heterocyclic compound featuring a reactive bromomethyl group attached to a pyrrolidin-2-one scaffold. This structure makes it a valuable intermediate in organic synthesis, particularly for the introduction of pyrrolidinone-based moieties in pharmaceuticals, agrochemicals, and specialty chemicals. The bromomethyl group facilitates further functionalization through nucleophilic substitution or cross-coupling reactions, enabling precise structural modifications. Its high purity and stability under controlled conditions ensure consistent performance in synthetic applications. The compound is particularly useful in the development of bioactive molecules, offering a balance of reactivity and selectivity for targeted molecular design. Proper handling is advised due to its potential sensitivity to moisture and light.
5-(bromomethyl)pyrrolidin-2-one structure
190271-85-3 structure
Product Name:5-(bromomethyl)pyrrolidin-2-one
CAS No:190271-85-3
MF:C5H8BrNO
MW:178.02712059021
MDL:MFCD04038517
CID:135018
PubChem ID:4059688
Update Time:2025-06-08

5-(bromomethyl)pyrrolidin-2-one Chemical and Physical Properties

Names and Identifiers

    • 2-Pyrrolidinone,5-(bromomethyl)-
    • 5-(bromomethyl)-2-Pyrrolidinone
    • 5-(bromomethyl)pyrrolidin-2-one
    • (R)-5-(Bromomethyl)-2-pyrrolidinone
    • AC1N363T
    • ACMC-209wph
    • ACMC-209yf6
    • AGN-PC-004TVW
    • CTK4E0345
    • SureCN125050
    • SCHEMBL125050
    • AKOS025243596
    • FT-0653545
    • MFCD04038517
    • MFCD01632456
    • MFCD06799465
    • SY066920
    • FT-0659291
    • SY033743
    • 190271-85-3
    • CS-0166600
    • SB44249
    • FT-0711601
    • 2-Pyrrolidinone, 5-(bromomethyl)-
    • W15281
    • EN300-195756
    • AB88641
    • DTXSID90398882
    • BOC-2-AMINO-1-CYCLOHEXANECARBOXYLICACID
    • AS-61427
    • DTXCID20349741
    • DB-011657
    • DB-065718
    • MDL: MFCD04038517
    • Inchi: 1S/C5H8BrNO/c6-3-4-1-2-5(8)7-4/h4H,1-3H2,(H,7,8)
    • InChI Key: QFOSFXPTXNRRMF-UHFFFAOYSA-N
    • SMILES: BrCC1CCC(N1)=O

Computed Properties

  • Exact Mass: 176.97894
  • Monoisotopic Mass: 176.979
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 8
  • Rotatable Bond Count: 1
  • Complexity: 105
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.4
  • Topological Polar Surface Area: 29.1?2

Experimental Properties

  • Density: 1.541
  • Boiling Point: 336.1 °C at 760 mmHg
  • Flash Point: 157.1 °C
  • PSA: 29.1

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5-(bromomethyl)pyrrolidin-2-one Suppliers

Amadis Chemical Company Limited
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(CAS:190271-85-3)5-(bromomethyl)pyrrolidin-2-one
Order Number:A1230719
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 21:37
Price ($):926

5-(bromomethyl)pyrrolidin-2-one Related Literature

Additional information on 5-(bromomethyl)pyrrolidin-2-one

Comprehensive Overview of 5-(Bromomethyl)pyrrolidin-2-one (CAS No. 190271-85-3)

5-(Bromomethyl)pyrrolidin-2-one (CAS No. 190271-85-3) is a versatile organic compound widely utilized in pharmaceutical and chemical research. This brominated derivative of pyrrolidin-2-one has garnered significant attention due to its unique reactivity and applications in synthesizing complex molecules. Researchers often search for "5-(Bromomethyl)pyrrolidin-2-one synthesis" or "CAS 190271-85-3 applications," reflecting its importance in modern organic chemistry.

The compound's molecular structure features a reactive bromomethyl group attached to a pyrrolidin-2-one ring, making it a valuable intermediate for nucleophilic substitution reactions. Its role in constructing nitrogen-containing heterocycles aligns with current trends in drug discovery, where "pyrrolidinone derivatives in medicine" is a trending topic. The compound's ability to serve as a building block for bioactive molecules has been explored in recent studies, particularly in targeting neurological and metabolic disorders.

From a synthetic perspective, 5-(Bromomethyl)pyrrolidin-2-one offers advantages in modular chemistry approaches. Queries like "pyrrolidin-2-one bromination methods" frequently appear in academic databases, highlighting the demand for optimized protocols. The compound's stability under various conditions makes it suitable for multi-step transformations, a feature highly valued in "green chemistry applications"—a hot topic in sustainable research.

Analytical characterization of CAS 190271-85-3 typically involves advanced techniques such as NMR spectroscopy and mass spectrometry. The scientific community shows growing interest in "spectral data for 5-(Bromomethyl)pyrrolidin-2-one," as evidenced by citation patterns. Recent publications have demonstrated its utility in creating novel polymer precursors, responding to the industrial demand for "functionalized pyrrolidinones in material science."

In pharmaceutical contexts, this compound serves as a key intermediate for N-heterocyclic scaffolds. The rise of "fragment-based drug design" has increased its relevance, with researchers investigating its potential in kinase inhibitor development. Safety profiles and handling procedures for 5-(Bromomethyl)pyrrolidin-2-one remain important considerations, as reflected in frequent searches for "CAS 190271-85-3 safety data" across chemical databases.

The commercial availability of 190271-85-3 has expanded significantly, addressing the needs of both academic and industrial laboratories. Market analyses show growing interest in "high-purity pyrrolidinone derivatives," particularly for applications in asymmetric synthesis. The compound's role in creating chiral auxiliaries connects with current research trends in "enantioselective catalysis," a field experiencing rapid growth.

Future research directions for 5-(Bromomethyl)pyrrolidin-2-one may explore its potential in bioconjugation chemistry, responding to the increasing demand for "protein-polymer hybrids" in biomedical applications. The compound's versatility ensures its continued importance in organic synthesis, as evidenced by persistent interest in "pyrrolidinone-based transformations" across chemical literature.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:190271-85-3)5-(bromomethyl)pyrrolidin-2-one
A1230719
Purity:99%
Quantity:1g
Price ($):926
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