Cas no 18812-40-3 (2-Iodothiophene-3-carbaldehyde)
2-Iodothiophene-3-carbaldehyde is a versatile heterocyclic building block used in organic synthesis, particularly in the construction of thiophene-based derivatives. Its key advantages include the presence of both an aldehyde group and an iodine substituent, which facilitate further functionalization via cross-coupling reactions, nucleophilic substitutions, or condensation reactions. The iodine atom enhances reactivity in palladium-catalyzed transformations, such as Suzuki or Sonogashira couplings, while the aldehyde group serves as a handle for condensation or reduction reactions. This compound is valuable in pharmaceutical and materials science research, enabling the synthesis of complex molecules with tailored properties. Its stability and well-defined reactivity make it a reliable intermediate for advanced synthetic applications.
18812-40-3 structure
Product Name:2-Iodothiophene-3-carbaldehyde
CAS No:18812-40-3
MF:C5H3IOS
MW:238.046192407608
MDL:MFCD03426915
CID:1090697
PubChem ID:819056
Update Time:2025-06-07
2-Iodothiophene-3-carbaldehyde Chemical and Physical Properties
Names and Identifiers
-
- 2-Iodothiophene-3-carbaldehyde
- 2-Iodo-3-thiophenecarbaldehyde
- 3-Thiophenecarboxaldehyde, 2-iodo-
- SBB098882
- FCH1335248
- AK143585
- AX8282833
- DS-7695
- 18812-40-3
- A908341
- SCHEMBL15888128
- AKOS022176404
- C73596
- AI-942/25121041
- DTXSID40356038
-
- MDL： MFCD03426915
- Inchi： 1S/C5H3IOS/c6-5-4(3-7)1-2-8-5/h1-3H
- InChI Key： XQBBCHBIMBAUEN-UHFFFAOYSA-N
- SMILES： IC1=C(C=O)C=CS1
Computed Properties
- Exact Mass: 237.89449
- Monoisotopic Mass: 237.89493g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 8
- Rotatable Bond Count: 1
- Complexity: 96.4
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.8
- Topological Polar Surface Area: 45.3
Experimental Properties
- Boiling Point: 278.9±25.0°C at 760 mmHg
- PSA: 17.07
2-Iodothiophene-3-carbaldehyde Security Information
- Signal Word：Warning
- Hazard Statement： H302-H315-H319-H335
- Warning Statement： P261-P305+P351+P338
- Storage Condition：Keep in dark place,Inert atmosphere,2-8°C
2-Iodothiophene-3-carbaldehyde Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-DE258-1g |
2-Iodothiophene-3-carbaldehyde |
18812-40-3 | 95+% | 1g |
3227.0CNY | 2021-07-12 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-DE258-100mg |
2-Iodothiophene-3-carbaldehyde |
18812-40-3 | 95+% | 100mg |
753CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-DE258-250mg |
2-Iodothiophene-3-carbaldehyde |
18812-40-3 | 95+% | 250mg |
1577CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-DE258-50mg |
2-Iodothiophene-3-carbaldehyde |
18812-40-3 | 95+% | 50mg |
416.0CNY | 2021-07-12 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-DE258-200mg |
2-Iodothiophene-3-carbaldehyde |
18812-40-3 | 95+% | 200mg |
1043.0CNY | 2021-07-12 | |
| Chemenu | CM127945-1g |
2-iodothiophene-3-carbaldehyde |
18812-40-3 | 95% | 1g |
$446 | 2023-02-17 | |
| Chemenu | CM127945-5g |
2-iodothiophene-3-carbaldehyde |
18812-40-3 | 95% | 5g |
$1075 | 2022-09-29 | |
| Ambeed | A433323-100mg |
2-Iodothiophene-3-carbaldehyde |
18812-40-3 | 95% | 100mg |
$102.00 | 2022-03-29 | |
| Ambeed | A433323-250mg |
2-Iodothiophene-3-carbaldehyde |
18812-40-3 | 95% | 250mg |
$160.00 | 2022-03-29 | |
| Ambeed | A433323-1g |
2-Iodothiophene-3-carbaldehyde |
18812-40-3 | 95% | 1g |
$399.0 | 2024-04-22 |
2-Iodothiophene-3-carbaldehyde Related Literature
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Fuming Xiao,Mengzhu Wang,Yunxiang Lei,Wenbo Dai,Yunbing Zhou,Miaochang Liu,Wenxia Gao,Xiaobo Huang,Huayue Wu J. Mater. Chem. C, 2020,8, 17410-17416
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J. M. Granadino-Roldán,M. Fernández-Gómez,A. Navarro,T. Pe?a Ruiz,U. A. Jayasooriya Phys. Chem. Chem. Phys., 2004,6, 1133-1143
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S. Amaresh,K. Karthikeyan,K. J. Kim,Y. S. Lee RSC Adv., 2014,4, 23107-23115
-
H. V. Jain,D. Verthelyi,S. L. Beaucage RSC Adv., 2017,7, 42519-42528
-
Eunhak Lim,Jiyoung Heo,Seong Keun Kim Nanoscale, 2019,11, 11369-11378
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