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• Solvents and Organic Chemicals Organic Compounds Alkaloids and derivatives Tropane alkaloids Tropane alkaloids
• Solvents and Organic Chemicals Organic Compounds Alkaloids and derivatives Tropane alkaloids

Compound CAS No. 18700-21-5: Endo-8-Methyl-8-Azabicyclo[3.2.1]Octan-6-Ol

The compound with CAS No. 18700-21-5, commonly referred to as endo-8-methyl-8-azabicyclo[3.2.1]octan-6-ol, is a structurally unique bicyclic amine alcohol with significant potential in various chemical and pharmaceutical applications. This compound belongs to the class of bicyclic amines, which are known for their rigid structures and diverse functional groups, making them valuable in drug design and material science.

The bicyclo[3.2.1]octane framework is a hallmark of this compound, characterized by its three fused rings: two five-membered rings and one six-membered ring. The endo configuration refers to the spatial arrangement of substituents within the bicyclic system, where the larger substituents are positioned on the same face of the molecule. This stereochemistry plays a crucial role in determining the compound's physical properties and reactivity.

Recent studies have highlighted the importance of endo-8-methyl substitution in modulating the electronic and steric properties of the molecule. The methyl group at position 8 introduces additional bulk, which can influence both the solubility and stability of the compound in various solvents. Furthermore, the hydroxyl group at position 6 (as indicated by "-ol" in the name) adds hydrophilic character to an otherwise hydrophobic bicyclic system, creating a balance that is often desirable in drug candidates.

From a synthetic perspective, endo-8-methyl-8-azabicyclo[3.2.1]octan-6-ol can be synthesized via various routes, including ring-closing metathesis and other cycloaddition reactions. These methods leverage the inherent reactivity of alkene groups to form the bicyclic structure under controlled conditions. The synthesis of such compounds often requires precise control over reaction conditions to achieve high yields and maintain stereochemical integrity.

In terms of applications, this compound has shown promise in several areas. In pharmaceutical chemistry, its rigid structure makes it an ideal candidate for exploring new drug delivery systems or as a scaffold for bioactive molecules targeting specific receptors or enzymes. Additionally, its unique combination of hydrophilic and hydrophobic groups makes it suitable for use in surfactants or as a building block in polymer chemistry.

Recent research has also explored the use of endo-bicyclic amines like this compound in catalysis, particularly in asymmetric catalysis where their chiral centers can induce enantioselectivity in reactions. The methyl group at position 8 serves as a key stereogenic element, influencing both the catalyst's activity and selectivity.

The study of CAS No. 18700-21-5 has also contributed to our understanding of bicyclic amine chemistry more broadly. By examining its reactivity under different conditions, chemists have gained insights into how substituent effects influence reaction pathways and outcomes.

In conclusion, endo-8-methyl-8 azabicyclo[3 2 1]octan 6 ol (CAS No: 18700 21 5) stands out as a versatile compound with significant potential across multiple fields due to its unique structure and functional groups.

• 171925-33-0(1,6,7-Indolizinetriol, octahydro-, 1S-(1.alpha.,6.beta.,7.alpha.,8a.beta.)-)
• 4839-11-6((3RS,6RS)-8-Methyl-8-azabicyclo[3.2.1]octane-3,6-diol)
• 20698-37-7(6-β-Hydroxyltropine)
• 617705-57-4(8-methyl-8-Azabicyclo[3.2.1]octan-6-ol)
• 65941-67-5((3RS,6RS)-8-Methyl-8-azabicyclo[3.2.1]octane-3,6-diol)
• 129724-72-7(1,6,8-Indolizinetriol,octahydro-, (1S,6S,8S,8aR)-)
• 125279-72-3((-)-Lentiginosine)
• 197501-52-3([S]-Octahydro-indolizin-1-ol)
• 787524-67-8(8-Azabicyclo[3.2.1]octan-6-ol,3-amino-8-methyl-(9CI))
• 20399-49-9((+-)-Tropan-3endo,6exo-diol)