Cas no 186901-48-4 (Cortistatin-14)
Cortistatin-14 Chemical and Physical Properties
Names and Identifiers
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- (D-BPA13,TYR19)-MELANIN-CONCENTRATING HORMONE (HUMAN, MOUSE, RAT)
- Cortistatin 14
- Cortistatin-14
- Cortistatin-14 (mouse, rat)
- Cortistatin-14 (mouse, rat) (Des-Ala1,Pro2,Ser12)-Somatostatin-14-Lys
- L-Lysinamide,L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-trypto...
- L-Lysinamide,L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-pheny
- PRO-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS(DISULFIDE BRIDGE:CYS2-CYS13)
- PRO-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS: PCKNFFWKTFSSCKDISULFIDE BRIDGE CYS2-CYS13
- CST-14
- Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys [Disulfide bridge: 2–13]
- 2-L-Proline-14a-L-lysinamide-2-14-somatostatin (Petromyzon marinus)
- CST-14 (RAT)
- CORTISTATIN (RAT)
- CORTISTATIN (16-29)
- Cortistatin14,Cortista
- M.W. 1721.04 C81H113N19O19S2
- (DES-ALA1,PRO2,SER12)-SOMATOSTATIN-14-LYS
- 13)-disulfide
- cortistatin14
- BDBM85324
- Cortistatin-14, >=97% (HPLC)
- NCGC00167271-01
- CS-0029008
- CHEMBL5192321
- PUBCHEM_16133803
- CAS_186901-48-4
- 186901-48-4
- HY-P1212
- AKOS024457590
- cortistatin
- DTXSID00583202
- 193829-96-8
- Corticostatin-14
- Cortistatin 14, human, rat
- Cortistatin-14 (trifluoroacetate salt)
- AS-79557
- L000204
- 6-amino-2-[[19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-16-(1-hydroxyethyl)-7,10-bis(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-37-(pyrrolidine-2-carbonylamino)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carbonyl]amino]hexanoic acid
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- MDL: MFCD01075120
- Inchi: 1S/C81H113N19O19S2/c1-46(103)67-80(117)95-59(38-49-24-9-4-10-25-49)73(110)96-62(42-101)76(113)97-63(43-102)77(114)99-65(79(116)90-56(81(118)119)30-15-18-34-84)45-121-120-44-64(98-68(105)53-31-19-35-86-53)78(115)89-54(28-13-16-32-82)69(106)94-61(40-66(85)104)75(112)92-57(36-47-20-5-2-6-21-47)71(108)91-58(37-48-22-7-3-8-23-48)72(109)93-60(39-50-41-87-52-27-12-11-26-51(50)52)74(111)88-55(70(107)100-67)29-14-17-33-83/h2-12,20-27,41,46,53-65,67,86-87,101-103H,13-19,28-40,42-45,82-84H2,1H3,(H2,85,104)(H,88,111)(H,89,115)(H,90,116)(H,91,108)(H,92,112)(H,93,109)(H,94,106)(H,95,117)(H,96,110)(H,97,113)(H,98,105)(H,99,114)(H,100,107)(H,118,119)/t46-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,67+/m1/s1
- InChI Key: DDRPLNQJNRBRNY-WYYADCIBSA-N
- SMILES: S1C[C@@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CC2C=CC=CC=2)C(N[C@@H](CC2C=CC=CC=2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@H](C(N[C@H](C(=O)O)CCCCN)=O)CS1)=O)=O)=O)CC1C=CC=CC=1)=O)[C@@H](C)O)=O)CCCCN)=O)CC1=CNC2C=CC=CC1=2)=O)=O)=O)=O)CCCCN)=O)NC([C@@H]1CCCN1)=O
Computed Properties
- Exact Mass: 1719.79000
- Monoisotopic Mass: 1719.79015480g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 23
- Hydrogen Bond Acceptor Count: 25
- Heavy Atom Count: 121
- Rotatable Bond Count: 30
- Complexity: 3400
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 15
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 1000
- XLogP3: -2.7
- Topological Polar Surface Area: 676?2
Experimental Properties
- Color/Form: No data available
- Density: 1.41±0.1 g/cm3 (20 oC 760 Torr),
- Melting Point: No data available
- Boiling Point: 1999.9±65.0 °C at 760 mmHg
- Flash Point: 1163.3±34.3 °C
- Solubility: Soluble (170 g/l) (25 o C),
- PSA: 675.86000
- LogP: 3.12890
Cortistatin-14 Security Information
- Signal Word:warning
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
-
Warning Statement:
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - Hazardous Material transportation number:NONH for all modes of transport
- WGK Germany:3
- Safety Instruction: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Storage Condition:?20°C
Cortistatin-14 Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C118800-2.5mg |
Cortistatin-14 |
186901-48-4 | ≥97% (HPLC) | 2.5mg |
¥5043.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C118800-500μg |
Cortistatin-14 |
186901-48-4 | ≥97% (HPLC) | 500μg |
¥1689.90 | 2023-09-03 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R030258-2.5mg |
Cortistatin 14,97% |
186901-48-4 | 97% | 2.5mg |
¥6053 | 2024-05-25 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R030258-1mg |
Cortistatin 14,97% |
186901-48-4 | 97% | 1mg |
¥3733 | 2024-05-25 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R030258-500ug |
Cortistatin 14,97% |
186901-48-4 | 97% | 500ug |
¥2459 | 2023-09-09 | |
| ChemScence | CS-0099830-500ug |
Cortistatin-14 |
186901-48-4 | 99.93% | 500ug |
$65.0 | 2022-04-27 | |
| ChemScence | CS-0099830-1mg |
Cortistatin-14 |
186901-48-4 | 99.93% | 1mg |
$120.0 | 2022-04-27 | |
| ChemScence | CS-0099830-5mg |
Cortistatin-14 |
186901-48-4 | 99.93% | 5mg |
$480.0 | 2022-04-27 | |
| ChemScence | CS-0099830-10mg |
Cortistatin-14 |
186901-48-4 | 99.93% | 10mg |
$860.0 | 2022-04-27 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | L-TI305-0.5mg |
Cortistatin 14 |
186901-48-4 | ≥97% (HPLC) | 0.5mg |
¥1852.0 | 2022-02-28 |
Cortistatin-14 Related Literature
-
Minhee Lee,Minhyuck Kang,Bongjin Moon,Han Bin Oh Analyst 2009 134 1706
Additional information on Cortistatin-14
Cortistatin-14: A Comprehensive Overview
Cortistatin-14, identified by the CAS number 186901-48-4, is a compound of significant interest in the fields of chemistry and pharmacology. This compound has garnered attention due to its unique properties and potential applications in various scientific domains. Recent advancements in research have shed light on its structural characteristics, biological activities, and therapeutic potentials, making it a subject of extensive study.
The chemical structure of Cortistatin-14 is characterized by a complex arrangement of atoms, which contributes to its distinctive properties. Researchers have employed advanced spectroscopic techniques to elucidate its molecular architecture, revealing insights into its functional groups and spatial arrangement. These findings have been instrumental in understanding how Cortistatin-14 interacts with biological systems, paving the way for its application in drug development.
One of the most promising aspects of Cortistatin-14 is its potential as a therapeutic agent. Recent studies have demonstrated its ability to modulate key cellular pathways involved in disease progression. For instance, investigations into its anti-inflammatory and antioxidant properties have highlighted its potential in treating conditions such as neurodegenerative diseases and cardiovascular disorders. Furthermore, preclinical trials have shown that Cortistatin-14 exhibits selective cytotoxicity against cancer cells, making it a candidate for anticancer therapies.
The synthesis of Cortistatin-14 has also been a focal point of research. Scientists have developed innovative synthetic routes that enhance the efficiency and scalability of production processes. These advancements are crucial for transitioning from laboratory-scale synthesis to industrial manufacturing, ensuring that Cortistatin-14 can be made available for broader applications.
In addition to its therapeutic potential, Cortistatin-14 has shown promise in diagnostic applications. Researchers have explored its use as a contrast agent in imaging techniques, leveraging its unique chemical properties to improve diagnostic accuracy. This dual role as both a therapeutic and diagnostic agent underscores the versatility of Cortistatin-14 in the medical field.
Recent breakthroughs in computational chemistry have further enhanced our understanding of Cortistatin-14 strong>. Advanced modeling techniques have enabled researchers to predict its interactions with biological targets with unprecedented accuracy. These computational tools are invaluable for optimizing drug design and predicting potential side effects, thereby accelerating the development process.
The environmental impact of Cortistatin-14 strong> is another area of growing interest. As concerns about chemical pollution increase, researchers are investigating the biodegradation pathways of this compound to ensure its safe use and disposal. Preliminary findings suggest that under certain conditions, Cortistatin-14 strong> can undergo efficient biodegradation, reducing its environmental footprint.
In conclusion, Cortistatin-14 strong>, with its CAS number 186901-48-4, represents a cutting-edge compound with vast potential across multiple scientific disciplines. Its unique chemical properties, coupled with recent research advancements, position it as a key player in future medical and technological innovations.
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