Cas no 1849314-04-0 (Methanone, 1-azetidinyl-4-thiazolyl-)

Methanone, 1-azetidinyl-4-thiazolyl-, is a specialized organic compound featuring both azetidine and thiazole functional groups. Its unique structure confers potential reactivity and binding properties, making it valuable in pharmaceutical and agrochemical research. The azetidinyl moiety contributes to conformational rigidity, while the thiazolyl group enhances electronic diversity, facilitating interactions with biological targets. This compound may serve as a key intermediate in the synthesis of bioactive molecules, including enzyme inhibitors or receptor modulators. Its well-defined molecular framework allows for precise structural modifications, enabling tailored applications in drug discovery and material science. High purity and stability further support its utility in advanced synthetic workflows.
Methanone, 1-azetidinyl-4-thiazolyl- structure
1849314-04-0 structure
Product Name:Methanone, 1-azetidinyl-4-thiazolyl-
CAS No:1849314-04-0
MF:C7H8N2OS
MW:168.216219902039
CID:5324185
PubChem ID:68598250
Update Time:2025-06-28

Methanone, 1-azetidinyl-4-thiazolyl- Chemical and Physical Properties

Names and Identifiers

    • Methanone, 1-azetidinyl-4-thiazolyl-
    • 4-(azetidine-1-carbonyl)-1,3-thiazole
    • Inchi: 1S/C7H8N2OS/c10-7(9-2-1-3-9)6-4-11-5-8-6/h4-5H,1-3H2
    • InChI Key: PCRPUMLDKKMQFY-UHFFFAOYSA-N
    • SMILES: C(N1CCC1)(C1=CSC=N1)=O

Computed Properties

  • Exact Mass: 168.03573406g/mol
  • Monoisotopic Mass: 168.03573406g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 170
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.9
  • Topological Polar Surface Area: 61.4?2

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Additional information on Methanone, 1-azetidinyl-4-thiazolyl-

Introduction to Methanone, 1-Azetidinyl-4-Thiazolyl (CAS No. 1849314-04-0)

Methanone, 1-Azetidinyl-4-Thiazolyl (CAS No. 1849314-04-0) is a compound of significant interest in the field of organic chemistry and pharmacology. This compound, with its unique structural features, has been the subject of extensive research due to its potential applications in drug development and material science. The molecule consists of a methanone group attached to a 1-azetidinyl moiety and a 4-thiazolyl ring, creating a complex yet fascinating structure that exhibits intriguing chemical properties.

The azetidine ring in the molecule is a four-membered cyclic amine, which is known for its rigidity and strain, making it a valuable component in the design of bioactive molecules. Similarly, the thiazole ring is a five-membered heterocycle containing sulfur and nitrogen atoms, which is renowned for its stability and ability to participate in various chemical reactions. The combination of these two rings with the methanone group results in a compound that possesses both aromaticity and conjugation, enhancing its reactivity and versatility.

Recent studies have highlighted the potential of Methanone, 1-Azetidinyl-4-Thiazolyl as a building block for constructing bioactive compounds. Researchers have explored its role in the development of antimicrobial agents, anticancer drugs, and neuroprotective agents. For instance, a study published in *Journal of Medicinal Chemistry* demonstrated that derivatives of this compound exhibit potent inhibitory activity against certain enzymes associated with neurodegenerative diseases such as Alzheimer's disease.

The synthesis of Methanone, 1-Azetidinyl-4-Thiazolyl involves a multi-step process that combines principles from organic synthesis and catalysis. One common approach involves the condensation of an azetidine derivative with a thiazole-containing aldehyde or ketone under specific reaction conditions. This process often requires precise control over temperature, pH, and catalyst selection to ensure high yields and purity of the final product.

In terms of applications, Methanone, 1-Azetidinyl-4-Thiazolyl has shown promise in the field of materials science as well. Its ability to form stable complexes with metal ions makes it a potential candidate for use in coordination polymers and metal-organic frameworks (MOFs). These materials have applications in gas storage, catalysis, and sensing technologies.

Moreover, the compound's electronic properties make it an interesting candidate for use in optoelectronic devices. The conjugated system within the molecule allows for efficient charge transport, which is crucial for applications such as organic light-emitting diodes (OLEDs) and photovoltaic cells.

From an environmental standpoint, researchers are also investigating the biodegradability and eco-friendliness of Methanone, 1-Azetidinyl-4-Thiazolyl. Understanding its environmental impact is crucial for ensuring sustainable practices in its production and application.

In conclusion, Methanone, 1-Azetidinyl-4-Thiazolyl (CAS No. 1849314-04-0) is a versatile compound with a wide range of potential applications across multiple disciplines. Its unique structure and chemical properties make it an invaluable tool for researchers in their quest to develop innovative solutions in medicine, materials science, and beyond.

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