Cas no 1848-69-7 (1-Phenylimidazolidin-2-one)

1-Phenylimidazolidin-2-one is a heterocyclic organic compound featuring an imidazolidin-2-one core substituted with a phenyl group at the 1-position. This structure imparts stability and reactivity, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. Its rigid framework is conducive to the development of bioactive molecules, particularly in the design of enzyme inhibitors and receptor modulators. The compound exhibits favorable solubility in common organic solvents, facilitating its use in diverse synthetic applications. Its well-defined chemical properties and consistent purity make it a reliable building block for research and industrial processes requiring precise molecular control.
1-Phenylimidazolidin-2-one structure
1-Phenylimidazolidin-2-one structure
Product Name:1-Phenylimidazolidin-2-one
CAS No:1848-69-7
MF:C9H10N2O
MW:162.188501834869
MDL:MFCD02671066
CID:158304
PubChem ID:255273
Update Time:2025-06-08

1-Phenylimidazolidin-2-one Chemical and Physical Properties

Names and Identifiers

    • 2-Imidazolidinone,1-phenyl-
    • 1-PHENYL-IMIDAZOLIDIN-2-ONE
    • 1-Phenylimidazolidin-2-one
    • 1-phenyl-2-imidazolidinon
    • 1-Phenyl-2-imidazolidinone
    • 1-Phenyl-imidazolidin-2-on
    • 2-Imidazolidinone,1-phenyl
    • 2-oxo-1-phenyl-imidazolidine
    • 3-Phenyl-2-imidazolidinone
    • 4,5-dihydro-1-phenylimidazol-2(1H)-one
    • N-phenyl-imidazolidinone
    • 2-Oxo-1-phenylimidazolidine, (2-Oxoimidazolidin-1-yl)benzene
    • 2-Imidazolidinone, 1-phenyl-
    • MLS002694410
    • QKKGTRSHKSWYAK-UHFFFAOYSA-N
    • NSC80633
    • N-phenylimidazolidone
    • phenyl imidazolin-2-one
    • 1-phenylimidazolidine-2-one
    • NCIOpen2_000752
    • 1-phenyl-2-oxo-imidazolidine
    • H
    • NSC-80633
    • DTXSID90292174
    • FT-0691150
    • A921233
    • 3,5-Dichloro-4-hydroxypyridine-2-carboxylicacid
    • MFCD02671066
    • W-206327
    • CHEMBL1893121
    • CS-0045323
    • Z1201621797
    • F2147-0743
    • HMS3089G12
    • AB92358
    • SMR001560339
    • PS-3080
    • 1-Phenyl-2-imidazolidinone, AldrichCPR
    • 1848-69-7
    • AKOS005257427
    • SCHEMBL146714
    • EN300-138401
    • MDL: MFCD02671066
    • Inchi: 1S/C9H10N2O/c12-9-10-6-7-11(9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)
    • InChI Key: QKKGTRSHKSWYAK-UHFFFAOYSA-N
    • SMILES: O=C1NCCN1C1C=CC=CC=1

Computed Properties

  • Exact Mass: 162.07900
  • Monoisotopic Mass: 162.079
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 175
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 32.299
  • XLogP3: 0.9

Experimental Properties

  • Density: 1.188
  • Boiling Point: °Cat760mmHg
  • Flash Point: °C
  • Refractive Index: 1.578
  • PSA: 32.34000
  • LogP: 1.61000

1-Phenylimidazolidin-2-one Security Information

  • Safety Instruction: 24/25
  • Hazardous Material Identification: Xi
  • Storage Condition:(BD60240)

1-Phenylimidazolidin-2-one Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-Phenylimidazolidin-2-one Pricemore >>

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1-Phenylimidazolidin-2-one Related Literature

Additional information on 1-Phenylimidazolidin-2-one

Comprehensive Overview of 1-Phenylimidazolidin-2-one (CAS No. 1848-69-7): Properties, Applications, and Industry Insights

1-Phenylimidazolidin-2-one (CAS No. 1848-69-7), a specialized organic compound, has garnered significant attention in pharmaceutical and chemical research due to its unique structural properties. This heterocyclic molecule features a phenyl group attached to an imidazolidin-2-one core, making it a versatile intermediate for synthesizing bioactive molecules. Researchers often search for "1-Phenylimidazolidin-2-one synthesis" or "CAS 1848-69-7 applications," reflecting its growing relevance in drug discovery and material science.

The compound's molecular formula (C9H10N2O) and weight (162.19 g/mol) align with its role as a building block for N-containing heterocycles. Its crystalline form and moderate solubility in polar solvents like ethanol or DMSO make it suitable for controlled reactions. Recent studies highlight its potential in designing kinase inhibitors and neurological agents, addressing trending topics such as "small molecule therapeutics" and "targeted drug delivery."

From an industrial perspective, 1-Phenylimidazolidin-2-one is pivotal in optimizing "green chemistry" processes. Manufacturers increasingly seek "sustainable synthesis routes for CAS 1848-69-7" to reduce environmental impact, aligning with global ESG (Environmental, Social, and Governance) trends. Advanced catalytic methods, including microwave-assisted reactions, have improved its production efficiency while minimizing waste.

Analytical characterization of this compound typically involves HPLC, NMR spectroscopy, and mass spectrometry, ensuring high purity (>98%) for research applications. Its stability under ambient conditions makes it a reliable candidate for long-term storage, though inert atmospheres are recommended for extended periods. Users frequently inquire about "1-Phenylimidazolidin-2-one safety data" and "handling precautions," emphasizing the need for transparent technical documentation.

In material science, derivatives of 1848-69-7 exhibit promising optical properties, spurring interest in "organic electronic materials" and "photoactive polymers." The compound's ability to modify electron density in conjugated systems supports innovations in OLEDs and sensors. Patent analyses reveal a steady rise in filings incorporating this scaffold, particularly in Asia-Pacific markets.

Regulatory compliance remains a key focus, with REACH and FDA guidelines governing its use in end products. Suppliers emphasizing "GMP-grade 1-Phenylimidazolidin-2-one" cater to pharmaceutical clients requiring stringent quality controls. The compound's non-hazardous classification under standard handling conditions enhances its adoption across labs.

Future research directions may explore 1-Phenylimidazolidin-2-one's role in covalent organic frameworks (COFs) or bioconjugation techniques. With AI-driven molecular modeling accelerating discovery, queries like "CAS 1848-69-7 in silico studies" are becoming prevalent. Collaborative efforts between academia and industry continue to unlock novel applications for this multifaceted compound.

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