Cas no 184221-86-1 (4-Bromo-8-methoxynaphthalen-1-ol)

4-Bromo-8-methoxynaphthalen-1-ol is a brominated naphthalene derivative featuring both methoxy and hydroxyl functional groups, making it a versatile intermediate in organic synthesis. Its distinct substitution pattern allows for selective reactivity in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, facilitating the construction of complex aromatic systems. The presence of both electron-donating (methoxy) and electron-withdrawing (bromo) groups enhances its utility in regioselective transformations. This compound is particularly valuable in pharmaceutical and materials chemistry, where it serves as a precursor for bioactive molecules or functional materials. High purity and well-defined reactivity ensure consistent performance in synthetic applications.
4-Bromo-8-methoxynaphthalen-1-ol structure
184221-86-1 structure
Product Name:4-Bromo-8-methoxynaphthalen-1-ol
CAS No:184221-86-1
MF:C11H9BrO2
MW:253.091962575912
MDL:MFCD27756708
CID:2950404
PubChem ID:10729529
Update Time:2025-10-22

4-Bromo-8-methoxynaphthalen-1-ol Chemical and Physical Properties

Names and Identifiers

    • 1-溴-5-甲氧基-4-萘酚
    • 1-Bromo-5-methoxy-4-naphthalenol
    • 4-broMo-8-Methoxynaphthalen-1-ol
    • 4-bromo-1-hydroxy-8-methoxynaphthalene
    • F15620
    • AKOS030528726
    • 184221-86-1
    • 4-Bromo-8-methoxynaphthalen-1-ol
    • MDL: MFCD27756708
    • Inchi: 1S/C11H9BrO2/c1-14-10-4-2-3-7-8(12)5-6-9(13)11(7)10/h2-6,13H,1H3
    • InChI Key: TZVRGUCTACOWMX-UHFFFAOYSA-N
    • SMILES: BrC1=CC=C(C2=C(C=CC=C21)OC)O

Computed Properties

  • Exact Mass: 251.97859Da
  • Monoisotopic Mass: 251.97859Da
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 1
  • Complexity: 198
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.5
  • Topological Polar Surface Area: 29.5

Experimental Properties

  • Density: 1.560±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 51-52 oC
  • Solubility: Almost insoluble (0.076 g/l) (25 o C),

4-Bromo-8-methoxynaphthalen-1-ol Pricemore >>

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