Cas no 18395-97-6 (Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl-)

Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- is a hexylene-bridged dichloromethylsilane compound characterized by its bifunctional structure. The molecule features two reactive dichloromethylsilyl groups linked by a six-carbon alkyl chain, enhancing its utility as a crosslinking or bridging agent in organosilicon chemistry. Its dichlorosilyl groups enable efficient hydrolysis and condensation reactions, making it suitable for applications in silicone polymer modification, surface functionalization, and adhesion promotion. The hexylene spacer provides flexibility and controlled spacing between reactive sites, facilitating tailored material properties. This compound is particularly valued for its stability, reactivity, and ability to serve as a precursor in the synthesis of specialized siloxane networks or hybrid materials.
Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- structure
18395-97-6 structure
Product Name:Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl-
CAS No:18395-97-6
MF:C8H18Cl4Si2
MW:312.211520671844
MDL:MFCD00054915
CID:122966
PubChem ID:15789907
Update Time:2025-06-08

Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- Chemical and Physical Properties

Names and Identifiers

    • 1,6-BIS(DICHLOROMETHYLSILYL)HEXANE
    • 2,2,9,9-Tetrachloro-2,9-disiladecane
    • Si,Si,Si',Si'-tetrachloro-Si,Si'-dimethyl-Si,Si'-hexanediyl-bis-silane
    • Si,Si,Si',Si'-Tetrachlor-Si,Si'-dimethyl-Si,Si'-hexandiyl-bis-silan
    • 1,6-Hexanediylbis(methyldichlorosilane)
    • dichloro-[6-[dichloro(methyl)silyl]hexyl]-methylsilane
    • MFCD00054915
    • 18395-97-6
    • SCHEMBL4262638
    • Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl-
    • MDL: MFCD00054915
    • Inchi: 1S/C8H18Cl4Si2/c1-13(9,10)7-5-3-4-6-8-14(2,11)12/h3-8H2,1-2H3
    • InChI Key: NDFFILGCGJJGOS-UHFFFAOYSA-N
    • SMILES: Cl[Si](C)(CCCCCC[Si](C)(Cl)Cl)Cl

Computed Properties

  • Exact Mass: 309.97000
  • Monoisotopic Mass: 309.970114g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 7
  • Complexity: 143
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 0?2

Experimental Properties

  • Density: 1,131 g/cm3
  • Boiling Point: 119 °C
  • PSA: 0.00000
  • LogP: 5.64600

Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- Security Information

  • Hazardous Material transportation number:UN 2987
  • Hazard Category Code: 34
  • Safety Instruction: S26; S36/37/39
  • Risk Phrases:R34

Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- Customs Data

  • HS CODE:2931900090
  • Customs Data:

    China Customs Code:

    2931900090

    Overview:

    2931900090. Other organic-Inorganic compound. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods). MFN tariff:6.5%. general tariff:30.0%

    Summary:

    2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
abcr
AB100081-25 g
1,6-Bis(dichloromethylsilyl)hexane, 95%; .
18395-97-6 95%
25 g
€72.10 2023-07-20
abcr
AB100081-25g
1,6-Bis(dichloromethylsilyl)hexane, 95%; .
18395-97-6 95%
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Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- Related Literature

Additional information on Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl-

Research Briefing on Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- (CAS: 18395-97-6) in Chemical Biomedicine

Recent advancements in chemical biomedicine have highlighted the significance of organosilicon compounds, particularly silane derivatives, in various applications ranging from drug delivery to biomaterial engineering. Among these, Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- (CAS: 18395-97-6) has emerged as a compound of interest due to its unique chemical properties and potential biomedical applications. This briefing synthesizes the latest research findings on this compound, focusing on its synthesis, characterization, and applications in the biomedical field.

The compound, with its dichloromethylsilane groups linked by a hexanediyl spacer, exhibits remarkable reactivity and stability, making it suitable for surface modification and cross-linking applications. Recent studies have explored its use in the functionalization of nanoparticles for targeted drug delivery systems. For instance, research published in the Journal of Materials Chemistry B demonstrated that surface modification of silica nanoparticles with this silane derivative significantly enhanced their biocompatibility and cellular uptake efficiency, paving the way for more effective cancer therapeutics.

Another critical area of investigation involves the role of Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- in the development of antimicrobial coatings. A 2023 study in ACS Applied Materials & Interfaces reported that coatings incorporating this compound exhibited potent antibacterial activity against multidrug-resistant strains, attributed to the release of chlorine species upon hydrolysis. This finding underscores its potential in combating hospital-acquired infections and improving medical device safety.

From a synthetic chemistry perspective, recent work has focused on optimizing the production of this silane derivative to achieve higher yields and purity. Advanced catalytic systems and greener synthetic routes have been explored, as documented in Organic Process Research & Development. These improvements are crucial for scaling up production to meet the growing demand in biomedical applications while minimizing environmental impact.

Looking forward, researchers are investigating the compound's potential in tissue engineering scaffolds, where its ability to form stable cross-links with biopolymers could enhance mechanical properties and bioactivity. Preliminary results from in vitro studies show promising compatibility with stem cells, suggesting applications in regenerative medicine. However, further in vivo studies are needed to fully assess its long-term biocompatibility and therapeutic efficacy.

In conclusion, Silane,1,1'-(1,6-hexanediyl)bis[1,1-dichloro-1-methyl- (18395-97-6) represents a versatile compound with significant potential in multiple biomedical domains. Ongoing research continues to uncover new applications and refine existing ones, positioning this silane derivative as a valuable tool in the advancement of chemical biomedicine. Future directions may include exploring its combination with other functional groups to create hybrid materials with tailored properties for specific medical applications.

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