• 1. Hydrogen transfer-induced S–C rearrangement in the molecular ion of thioanisole derivatives with site-specificity
  Qi Yin,Yi Wang,Xinchi Yin,Yuanjiang Pan Analyst 2021 146 6315
• 2. Comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry for the screening of potent swampy/septic odor-causing compounds in two drinking water sources in China
  Qingyuan Guo,Xia Li,Jianwei Yu,Haifeng Zhang,Yu Zhang,Min Yang,Ning Lu,Dong Zhang Anal. Methods 2015 7 2458
• 3. Transition-metal-free cross-coupling of thioethers with aryl(cyano)iodonium triflates: a facile and efficient method for the one-pot synthesis of thiocyanates
  Dan Zhu,Denghu Chang,Lei Shi Chem. Commun. 2015 51 7180
• 4. Rapid simultaneous determination of organochlorine and pyrethroid pesticide residues in Lycium barbarum L. using gas chromatography with electron-capture detector
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• Solvents and Organic Chemicals Organic Compounds Organosulfur compounds Thioethers Aryl thioethers

Pentachlorothioanisole (CAS No. 1825-19-0): A Comprehensive Overview of Its Properties and Applications

Pentachlorothioanisole (CAS No. 1825-19-0), also known as PCTA, is a sulfur-containing aromatic compound with significant industrial and research relevance. This chlorinated derivative of thioanisole has garnered attention due to its unique chemical structure and diverse applications. In recent years, the compound has been studied for its potential roles in organic synthesis, material science, and environmental chemistry. Researchers and industry professionals often search for terms like "Pentachlorothioanisole uses", "CAS 1825-19-0 safety data", and "PCTA synthesis methods", reflecting growing interest in its properties and applications.

The molecular formula of Pentachlorothioanisole is C₇H₃Cl₅S, featuring a thioether group (-S-) attached to a pentachlorinated benzene ring. This structure imparts notable stability and reactivity, making it a valuable intermediate in organosulfur chemistry. Recent advancements in green chemistry have sparked discussions about sustainable synthesis routes for such compounds, aligning with global trends toward eco-friendly industrial processes. Searches for "eco-friendly PCTA production" and "Pentachlorothioanisole biodegradability" highlight this shift in focus.

One of the key applications of Pentachlorothioanisole lies in its role as a building block for specialty chemicals. Its ability to undergo selective substitution reactions makes it useful in designing advanced materials, such as liquid crystals and polymers. Additionally, its electronic properties have been explored in optoelectronic devices, a topic frequently searched alongside terms like "PCTA in electronics" and "CAS 1825-19-0 material science". The compound's stability under various conditions also makes it a candidate for catalysis and surface modification studies.

From an analytical perspective, Pentachlorothioanisole is often used as a reference standard in chromatography and mass spectrometry. Laboratories worldwide rely on its well-characterized properties for calibrating instruments and validating methods. This has led to increased searches for "Pentachlorothioanisole HPLC methods" and "CAS 1825-19-0 analytical standards". The compound's detectability at low concentrations also makes it relevant in environmental monitoring, particularly in studies tracking persistent organic pollutants (POPs).

Recent studies have examined the structure-activity relationships of Pentachlorothioanisole derivatives, exploring how subtle modifications affect their physical and chemical behavior. Such investigations are crucial for developing tailored compounds with specific functionalities. The rise of computational chemistry has further accelerated this research, with queries like "PCTA molecular modeling" and "CAS 1825-19-0 DFT studies" becoming more common in academic circles.

In terms of handling and storage, Pentachlorothioanisole requires standard precautions typical of organochlorine compounds. Proper ventilation and personal protective equipment (PPE) are recommended when working with this material. While not classified as highly hazardous, its environmental persistence warrants responsible disposal practices—a concern reflected in searches for "PCTA waste management" and "CAS 1825-19-0 handling guidelines".

The commercial availability of Pentachlorothioanisole has expanded in recent years, with suppliers offering various purity grades to meet different research and industrial needs. This accessibility has facilitated broader investigation into its potential applications, from pharmaceutical intermediates to agrochemical precursors. Market analyses show growing interest in "Pentachlorothioanisole suppliers" and "CAS 1825-19-0 price trends", indicating its rising importance in specialty chemical markets.

Looking ahead, research on Pentachlorothioanisole is likely to focus on derivative development and process optimization. As industries seek more sustainable chemical solutions, innovations in catalytic synthesis and waste minimization for compounds like PCTA will remain critical. The intersection of traditional chemistry with emerging fields like nanotechnology may unlock novel applications for this versatile compound, ensuring its continued relevance in scientific and industrial contexts.

• 4163-78-4(2,4,5-Trichlorothioanisole)
• 98420-62-3(Benzene,1,2,3-trichloro-4-(methylthio)-)
• 36731-42-7(Benzene,tetrachlorobis(methylthio)- (9CI))
• 67341-47-3(1,4-bis(methylthio)-2,3,5,6-tetrachlorobenzene)
• 62601-17-6(Benzene,1,2,3,4,5-pentachloro-6-[(chloromethyl)thio]-)
• 2227-13-6(Tetrasul)
• 98464-63-2(Benzene,1,2,5-trichloro-3-(methylthio)-)
• 68671-90-9(2,3,5,6-Tetrachlorothioanisole)
• 149858-94-6(Benzene, 1,1'-thiobis-,trichloro deriv. (9CI))
• 65909-82-2(2,4-DICHLOROBENZYL MERCAPTAN)