Cas no 182499-90-7 (2-Amino-5-ethylphenol)

2-Amino-5-ethylphenol is an aromatic organic compound featuring both amino and hydroxyl functional groups on a benzene ring substituted with an ethyl group. This structure lends it utility as an intermediate in the synthesis of dyes, pharmaceuticals, and specialty chemicals. Its reactive sites enable participation in coupling, acylation, and alkylation reactions, making it valuable for fine chemical manufacturing. The ethyl substituent enhances solubility in organic solvents, facilitating its use in synthetic processes. Careful handling is required due to potential sensitivity to oxidation. The compound is typically supplied as a solid with purity levels tailored to industrial or research applications, ensuring consistent performance in synthetic workflows.
2-Amino-5-ethylphenol structure
2-Amino-5-ethylphenol structure
Product Name:2-Amino-5-ethylphenol
CAS No:182499-90-7
MF:C8H11NO
MW:137.179042100906
MDL:MFCD06408244
CID:113872
PubChem ID:4712167
Update Time:2025-06-08

2-Amino-5-ethylphenol Chemical and Physical Properties

Names and Identifiers

    • Phenol,2-amino-5-ethyl-
    • 2-Amino-5-ethylphenol
    • 2-amino-5-ethyl-phenol
    • 4-amino-3-hydroxy(ethyl)benzene
    • 5-ethyl-2-aminophenol
    • AC1NFQ21
    • AG-A-36381
    • CTK6D1181
    • SureCN454989
    • Phenol, 2-amino-5-ethyl- (9CI)
    • 2-Amino-5-ethyl-phenol, AldrichCPR
    • SCHEMBL454989
    • CS-0342384
    • AS-77101
    • DTXSID40405691
    • VBCFPAKCBOGUBW-UHFFFAOYSA-N
    • AKOS006337173
    • PHENOL, 2-AMINO-5-ETHYL-
    • n-(p-(difluoromethoxy)phenyl)-anthranilicaci
    • 1-amino 2-hydroxy 4-ethylbenzene
    • FT-0709391
    • D82162
    • 182499-90-7
    • MFCD06408244
    • MB03784
    • MDL: MFCD06408244
    • Inchi: 1S/C8H11NO/c1-2-6-3-4-7(9)8(10)5-6/h3-5,10H,2,9H2,1H3
    • InChI Key: VBCFPAKCBOGUBW-UHFFFAOYSA-N
    • SMILES: OC1=C(C=CC(=C1)CC)N

Computed Properties

  • Exact Mass: 137.08413
  • Monoisotopic Mass: 137.084063974g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 105
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.7
  • Topological Polar Surface Area: 46.2?2

Experimental Properties

  • Density: 1.116
  • Boiling Point: 254.829 °C at 760 mmHg
  • Flash Point: 107.917 °C
  • PSA: 46.25

2-Amino-5-ethylphenol Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd.
20R0913-1g
2-Amino-5-ethyl-phenol
182499-90-7 96%
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JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd.
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TRC
A633778-50mg
2-Amino-5-ethylphenol
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$ 50.00 2022-06-07
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$ 95.00 2022-06-07
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abcr
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€224.60 2023-04-14
abcr
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eNovation Chemicals LLC
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Additional information on 2-Amino-5-ethylphenol

2-Amino-5-Ethylphenol: A Comprehensive Overview

2-Amino-5-Ethylphenol, also known by its CAS number 182499-90-7, is a versatile organic compound with significant applications in various fields of chemistry and materials science. This compound, characterized by its unique structure featuring an amino group and an ethyl substituent on a phenol ring, has garnered attention due to its potential in drug design, polymer synthesis, and as an intermediate in chemical manufacturing. Recent advancements in synthetic methodologies and its biological evaluations have further highlighted its importance in contemporary research.

The molecular structure of 2-Amino-5-Ethylphenol consists of a benzene ring with hydroxyl (-OH) and amino (-NH2) groups at the 2nd and 5th positions, respectively, along with an ethyl group attached at the 5th position. This arrangement imparts the compound with unique electronic properties, making it a valuable substrate for various chemical transformations. The presence of both amino and hydroxyl groups allows for multiple reaction pathways, including nucleophilic substitutions, condensations, and oxidations, which are exploited in diverse synthetic strategies.

Recent studies have focused on the synthesis of 2-Amino-5-Ethylphenol via novel routes that enhance yield and selectivity. For instance, researchers have employed catalytic hydrogenation techniques to streamline the production process, reducing both time and cost. Additionally, green chemistry approaches have been integrated into its synthesis, utilizing renewable feedstocks and minimizing environmental impact. These advancements underscore the compound's relevance in sustainable chemical manufacturing.

In the pharmaceutical industry, 2-Amino-5-Ethylphenol has shown promise as a lead compound for drug development. Its ability to act as a bioisostere or pharmacophore mimic makes it a valuable tool in medicinal chemistry. Recent research has explored its potential as an anti-inflammatory agent, leveraging its ability to modulate key enzymes involved in inflammatory pathways. Furthermore, studies into its antioxidant properties suggest applications in neuroprotective therapies, where oxidative stress plays a pivotal role.

The material science sector has also benefited from the properties of 2-Amino-5-Ethylphenol. Its use as a precursor in polymer synthesis has led to the development of novel materials with enhanced mechanical and thermal stability. Researchers have successfully incorporated this compound into polyurethane formulations, resulting in materials with improved durability under harsh conditions. Such innovations highlight its role as a key building block in advanced material engineering.

Beyond these applications, 2-Amino-5-Ethylphenol has emerged as an important intermediate in the synthesis of more complex organic molecules. Its ability to undergo multiple functional group transformations makes it indispensable in multi-step synthesis protocols. Recent advancements have seen its use in the construction of heterocyclic compounds, which are critical components in modern drug discovery.

In conclusion, 2-Amino-5-Ethylphenol (CAS No: 182499-90-7) stands as a testament to the versatility of organic compounds in modern science. With ongoing research uncovering new synthetic pathways and expanding its application domains, this compound continues to be a focal point for innovation across multiple disciplines. Its role as both a functional material and a pharmacological agent ensures that it remains at the forefront of chemical research for years to come.

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