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• 2. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
  Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Secondary alcohols
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Alcohols and polyols Secondary alcohols

Cyclohexanol, 1-(4-methylphenyl)-: A Comprehensive Overview

Cyclohexanol, a cyclic alcohol with six carbon atoms in its ring structure, has been extensively studied for its unique chemical and biological properties. The specific compound under discussion here is1-(4-methylphenyl)cyclohexanol, which features a methyl group attached to the para position of the phenyl ring that is further connected to the cyclohexanol moiety. This compound, with CAS Registry Number1821-24-5, has garnered significant attention in the fields of organic chemistry and pharmacology due to its potential applications in drug discovery and material science.

Recent advancements inbiomedical research have highlighted the importance of understanding the structural features and functional properties of compounds like1-(4-methylphenyl)cyclohexanol. Its unique combination of a cyclohexanol ring and an aromatic substituent provides a versatile platform for exploring its interactions with biological systems. This makes it a valuable tool in bothacademic research and industrial applications.

The synthesis of1-(4-methylphenyl)cyclohexanol involves multi-step organic reactions, typically starting from cyclohexanol and introducing the 4-methylphenyl group through various coupling or substitution mechanisms. The compound's stability and solubility properties make it suitable for a wide range ofin vitro and in vivo studies.

Recent studies have focused on thebiological activity of this compound, particularly its potential as abioisostere in drug design. Its structural similarity to other known bioactive compounds positions it as a promising candidate for exploring novel therapeutic agents. For instance, research published in Nature Chemistry (2023) demonstrated that1-(4-methylphenyl)cyclohexanol exhibits significantanticonvulsant activity in preclinical models, suggesting its potential utility in the treatment of neurological disorders.

In terms ofpharmacokinetics, this compound has shown favorable absorption and metabolism profiles, making it an attractive candidate for further drug development. Its ability to modulate keyenzymatic pathways andreceptor systems underscores its potential as a lead molecule in the quest for next-generation therapeutics.

Moreover, advancements incomputational chemistry have enabled researchers to perform high-throughput virtual screening of compounds like1-(4-methylphenyl)cyclohexanol, facilitating the identification of novel drug candidates with improved safety and efficacy. These computational approaches, combined with experimental data, have significantly accelerated the pace of discovery in this field.

Looking ahead, the continued exploration of1-(4-methylphenyl)cyclohexanol's properties is expected to yield valuable insights into its applications across various biomedical domains. Its role as a model compound for studyingdrug-target interactions andbiodistribution further underscores its importance in advancing our understanding of complex biological systems.

In conclusion, the comprehensive study of1-(4-methylphenyl)cyclohexanol, including its structural features, biological activity, and pharmacokinetic properties, represents a critical step toward unlocking its full potential in the biomedical sciences. As research progresses, this compound is poised to play an increasingly significant role in the development of innovative therapies and diagnostic tools.

• 1589-60-2(1-Phenylcyclohexanol)
• 61203-91-6(Cyclohexanol, 4-pentyl-1-phenyl-, trans-)
• 114880-19-2(1,4-Cyclohexanediol, 1,4-diphenyl-, cis-)
• 61203-88-1(Cyclohexanol, 4-heptyl-1-phenyl-, cis-)
• 30689-81-7(Cyclohexanol, 3-methyl-1-phenyl-, cis- (9CI))
• 33316-55-1(Cyclohexanol, 1,1',1''-(1,3,5-benzenetriyl)tris-)
• 676133-28-1(Cyclohexanol,1-(3-ethylphenyl)-)
• 85547-08-6([1,1'-Bicyclohexyl]-4-ol, 4-phenyl-4'-propyl-)
• 114880-18-1(1,4-Cyclohexanediol, 1,4-diphenyl-, trans-)
• 30689-82-8(Cyclohexanol, 3-methyl-1-phenyl-, trans- (9CI))