Cas no 18088-01-2 ((2,6-Dimethylpyridin-4-yl)methanol)

(2,6-Dimethylpyridin-4-yl)methanol is a pyridine derivative featuring a hydroxymethyl functional group at the 4-position and methyl substituents at the 2- and 6-positions. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and coordination complexes. Its sterically hindered pyridine core enhances stability, while the hydroxymethyl group offers a reactive site for further functionalization, such as esterification or oxidation. The compound’s defined structure and purity make it suitable for precise applications in medicinal chemistry and catalysis. Its solubility in common organic solvents facilitates handling in synthetic workflows. Storage under inert conditions is recommended to maintain stability.
(2,6-Dimethylpyridin-4-yl)methanol structure
18088-01-2 structure
Product Name:(2,6-Dimethylpyridin-4-yl)methanol
CAS No:18088-01-2
MF:C8H11NO
MW:137.179042100906
MDL:MFCD00956275
CID:135876
PubChem ID:3825077
Update Time:2025-10-28

(2,6-Dimethylpyridin-4-yl)methanol Chemical and Physical Properties

Names and Identifiers

    • (2,6-Dimethylpyridin-4-yl)methanol
    • 2,6-Dimethyl-4-(hydroxymethyl)pyridine
    • 2,6-Dimethyl-4-pyridylmethanol
    • 4-Pyridinemethanol,2,6-dimethyl-
    • 4-Hydroxymethyl-2,6-lutidine
    • FT-0685540
    • (2,6-dimethyl-4-pyridyl)methanol
    • 18088-01-2
    • AB86594
    • 4-Pyridinemethanol, 2,6-dimethyl-
    • AKOS005255193
    • (2,6-dimethyl-4-pyridinyl)methanol
    • MFCD00956275
    • AM85637
    • 2,6-dimethyl-4-pyridinemethanol
    • A812568
    • 4-Hydroxymethyl-2,6-dimethylpyridine
    • (2,6-Dimethyl-pyridin-4-yl)-methanol
    • W-206290
    • 4-(Hydroxymethyl)-2,6-dimethylpyridine
    • DTXSID50396925
    • AC-23055
    • TS-01776
    • SCHEMBL377724
    • DLDGHMPQNVTNRC-UHFFFAOYSA-N
    • DB-082734
    • BBL100736
    • STL554530
    • MDL: MFCD00956275
    • Inchi: 1S/C8H11NO/c1-6-3-8(5-10)4-7(2)9-6/h3-4,10H,5H2,1-2H3
    • InChI Key: DLDGHMPQNVTNRC-UHFFFAOYSA-N
    • SMILES: OCC1C=C(C)N=C(C)C=1

Computed Properties

  • Exact Mass: 137.08400
  • Monoisotopic Mass: 137.084063974g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 95.4
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.6
  • Topological Polar Surface Area: 33.1?2

Experimental Properties

  • Density: 1.063±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 102-103 oC
  • Boiling Point: 242.7±35.0 oC (760 Torr),
  • Flash Point: 100.6±25.9 oC,
  • Solubility: Dissolution (62 g/l) (25 o C),
  • PSA: 33.12000
  • LogP: 1.19070

(2,6-Dimethylpyridin-4-yl)methanol Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Additional information on (2,6-Dimethylpyridin-4-yl)methanol

(2,6-Dimethylpyridin-4-yl)methanol: A Comprehensive Overview

(2,6-Dimethylpyridin-4-yl)methanol, also known by its CAS number 18088-01-2, is a chemical compound that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound is characterized by its unique structure, which combines a pyridine ring with two methyl groups at the 2 and 6 positions and a hydroxymethyl group at the 4 position. The molecule's structure not only imparts it with interesting physical and chemical properties but also positions it as a valuable intermediate in the synthesis of various bioactive compounds.

The synthesis of (2,6-Dimethylpyridin-4-yl)methanol has been extensively studied, with researchers exploring various methods to optimize its production. Recent advancements have focused on green chemistry approaches, such as using catalytic hydrogenation or enzymatic reactions, to enhance yield and reduce environmental impact. These methods not only improve the efficiency of synthesis but also align with the growing demand for sustainable chemical processes in the industry.

In terms of applications, (2,6-Dimethylpyridin-4-yl)methanol has shown promise in the pharmaceutical sector. Its ability to act as a chiral auxiliary in asymmetric synthesis has made it a valuable tool for constructing complex molecules with high enantiomeric excess. This property is particularly advantageous in drug discovery, where the stereochemistry of compounds plays a critical role in their efficacy and safety.

Recent studies have also highlighted the potential of (2,6-Dimethylpyridin-4-yl)methanol in materials science. Researchers have investigated its use as a building block for constructing functional polymers and nanoparticles. These materials exhibit unique optical and electronic properties, making them suitable for applications in sensors, drug delivery systems, and advanced electronics.

The physical properties of (2,6-Dimethylpyridin-4-yl)methanol are equally intriguing. It has a melting point of approximately 55°C and a boiling point around 155°C under standard conditions. The compound is sparingly soluble in water but exhibits good solubility in organic solvents such as dichloromethane and ethyl acetate. These properties make it amenable to various analytical techniques, including high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy.

From a safety standpoint, (2,6-Dimethylpyridin-4-yl)methanol is classified as non-hazardous under normal handling conditions. However, it is recommended to handle the compound with appropriate personal protective equipment (PPE) to minimize exposure risks. Proper storage in a cool, dry place away from direct sunlight is also advised to maintain its stability.

In conclusion, (2,6-Dimethylpyridin-4-yl)methanol (CAS No. 18088-01-2) is a versatile compound with a wide range of applications across multiple disciplines. Its unique structure, coupled with advancements in synthesis and application techniques, continues to drive innovation in both academic research and industrial settings. As research into this compound progresses, it is anticipated that new discoveries will further expand its utility in diverse fields.

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