Cas no 1807854-17-6 (Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride)

Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride is a structurally unique amine derivative featuring a rigid bicyclo[1.1.1]pentane scaffold. This compound is valued in medicinal chemistry and drug discovery for its role as a bioisostere, effectively replacing traditional aromatic or aliphatic groups to enhance metabolic stability and reduce steric hindrance. The hydrochloride salt form improves solubility and handling for synthetic applications. Its strained bicyclic framework confers high reactivity, making it a versatile intermediate for cross-coupling reactions and fragment-based drug design. The compound is particularly useful in optimizing pharmacokinetic properties while maintaining target affinity in small-molecule therapeutics.
Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride structure
1807854-17-6 structure
Product Name:Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride
CAS No:1807854-17-6
MF:C6H12ClN
MW:133.619180679321
CID:4708281
PubChem ID:117273105
Update Time:2025-06-10

Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride Chemical and Physical Properties

Names and Identifiers

    • bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride
    • Bicyclo[1.1.1]pentane-1-methanamine hydrochloride
    • Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride
    • Inchi: 1S/C6H11N.ClH/c7-4-6-1-5(2-6)3-6;/h5H,1-4,7H2;1H
    • InChI Key: XEDGCBXYNYJDNT-UHFFFAOYSA-N
    • SMILES: Cl.NCC12CC(C1)C2

Computed Properties

  • Exact Mass: 97.089149355g/mol
  • Monoisotopic Mass: 97.089149355g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 8
  • Rotatable Bond Count: 1
  • Complexity: 81.3
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 26
  • XLogP3: 0.3

Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride Pricemore >>

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Additional information on Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride

Introduction to Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride (CAS No. 1807854-17-6)

Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride, with the chemical formula corresponding to its CAS number 1807854-17-6, is a compound that has garnered significant attention in the field of pharmaceutical research and development. This compound belongs to a class of molecules known for their unique structural properties, which make them promising candidates for various biological applications.

The structure of Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride features a bicyclic framework, specifically a three-membered ring connected to a five-membered ring, which contributes to its distinct chemical and biological characteristics. The presence of an amine group and its salt form (hydrochloride) further enhances its solubility and reactivity, making it a versatile intermediate in synthetic chemistry.

In recent years, there has been growing interest in the development of novel compounds that can interact with biological targets in unique ways. The bicyclo[1.1.1]pentan scaffold has been explored for its potential in drug design due to its ability to mimic certain natural products and exhibit favorable pharmacokinetic properties. This compound, in particular, has been studied for its potential applications in the treatment of various diseases, including neurological disorders and infectious diseases.

One of the most compelling aspects of Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride is its role as a building block in the synthesis of more complex molecules. Researchers have leveraged its structural features to develop novel analogs with enhanced biological activity. For instance, modifications to the amine group have been shown to influence binding affinity and selectivity towards specific targets, making this compound a valuable tool in medicinal chemistry.

The hydrochloride salt form of this compound improves its stability and bioavailability, which are critical factors in drug development. This makes Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride an attractive candidate for further investigation in preclinical studies. Several research groups have reported on the synthesis and characterization of derivatives based on this scaffold, demonstrating its potential as a lead compound for new therapeutic agents.

Recent studies have also highlighted the importance of understanding the metabolic pathways and interactions of such compounds within biological systems. The unique structural features of Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride suggest that it may interact with enzymes and receptors in ways that differ from traditional small molecules. This has opened up new avenues for research into drug mechanisms and potential side effects.

The development of computational models and high-throughput screening techniques has further accelerated the discovery process for compounds like Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride. These tools allow researchers to predict biological activity and optimize molecular structures more efficiently than ever before. As a result, there is considerable excitement about the future prospects of this compound in both academic research and industrial applications.

In conclusion, Bicyclo[1.1.1]pentan-1-ylmethanamine hydrochloride (CAS No. 1807854-17-6) represents a significant advancement in pharmaceutical chemistry due to its unique structural properties and potential biological applications. Its role as a versatile intermediate and lead compound continues to inspire innovation in drug discovery and development. As research progresses, it is likely that new insights into its mechanisms of action and therapeutic potential will emerge, further solidifying its importance in the field.

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