Cas no 1806863-16-0 (4-Amino-2-chloro-3-(chloromethyl)pyridine)
4-Amino-2-chloro-3-(chloromethyl)pyridine is a versatile heterocyclic compound featuring both amino and chloromethyl functional groups, making it a valuable intermediate in organic synthesis and pharmaceutical applications. Its reactive sites enable selective modifications, facilitating the development of complex molecules, including active pharmaceutical ingredients (APIs) and agrochemicals. The presence of chlorine substituents enhances its utility in nucleophilic substitution reactions, while the amino group allows for further derivatization. This compound is particularly useful in the synthesis of pyridine-based scaffolds, offering chemists a robust building block for drug discovery and material science. Its stability and well-defined reactivity profile contribute to its reliability in multi-step synthetic routes.
1806863-16-0 structure
Product Name:4-Amino-2-chloro-3-(chloromethyl)pyridine
CAS No:1806863-16-0
MF:C6H6Cl2N2
MW:177.031239032745
CID:4803548
Update Time:2025-10-17
4-Amino-2-chloro-3-(chloromethyl)pyridine Chemical and Physical Properties
Names and Identifiers
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- 4-Amino-2-chloro-3-(chloromethyl)pyridine
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- Inchi: 1S/C6H6Cl2N2/c7-3-4-5(9)1-2-10-6(4)8/h1-2H,3H2,(H2,9,10)
- InChI Key: HPXFYXZTUGTRGG-UHFFFAOYSA-N
- SMILES: ClCC1C(=NC=CC=1N)Cl
Computed Properties
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 10
- Rotatable Bond Count: 1
- Complexity: 110
- XLogP3: 1.5
- Topological Polar Surface Area: 38.9
4-Amino-2-chloro-3-(chloromethyl)pyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029016207-250mg |
4-Amino-2-chloro-3-(chloromethyl)pyridine |
1806863-16-0 | 95% | 250mg |
$1,029.00 | 2022-03-31 | |
| Alichem | A029016207-1g |
4-Amino-2-chloro-3-(chloromethyl)pyridine |
1806863-16-0 | 95% | 1g |
$3,155.55 | 2022-03-31 |
4-Amino-2-chloro-3-(chloromethyl)pyridine Related Literature
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Quan Xiang,Yiqin Chen,Zhiqin Li,Kaixi Bi,Guanhua Zhang,Huigao Duan Nanoscale, 2016,8, 19541-19550
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Huiying Xu,Lu Zheng,Yu Zhou,Bang-Ce Ye Analyst, 2021,146, 5542-5549
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Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
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Chengbin Yang,Hing Lun Tsang,Pui Man Lau,Ken-Tye Yong,Ho Pui Ho,Siu Kai Kong Analyst, 2017,142, 3579-3587
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