Cas no 1806033-05-5 (2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine)

2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine is a halogenated pyridine derivative with a unique substitution pattern, offering versatile reactivity for synthetic applications. The presence of bromo and chloro groups at the 2- and 4-positions provides selective sites for further functionalization, while the difluoromethyl and trifluoromethyl groups enhance its lipophilicity and metabolic stability. This compound is particularly valuable in agrochemical and pharmaceutical research, where fluorinated pyridines are sought after for their bioactivity and resistance to degradation. Its well-defined structure makes it a useful intermediate in the development of advanced heterocyclic compounds, enabling precise modifications for targeted applications.
2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine structure
1806033-05-5 structure
Product Name:2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine
CAS No:1806033-05-5
MF:C7H2BrClF5N
MW:310.446497440338
CID:4810238
Update Time:2025-10-28

2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine Chemical and Physical Properties

Names and Identifiers

    • 2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine
    • Inchi: 1S/C7H2BrClF5N/c8-5-4(6(10)11)2(9)1-3(15-5)7(12,13)14/h1,6H
    • InChI Key: XGXPGLBORHMPGI-UHFFFAOYSA-N
    • SMILES: BrC1=C(C(F)F)C(=CC(C(F)(F)F)=N1)Cl

Computed Properties

  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 1
  • Complexity: 224
  • XLogP3: 4
  • Topological Polar Surface Area: 12.9

2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A029063298-1g
2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine
1806033-05-5 97%
1g
$1,534.70 2022-04-01

Additional information on 2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine

Comprehensive Overview of 2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine (CAS No. 1806033-05-5)

2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine (CAS No. 1806033-05-5) is a highly specialized halogenated pyridine derivative that has garnered significant attention in the fields of agrochemicals, pharmaceutical intermediates, and material science. This compound, characterized by its unique polyfluorinated and brominated structure, exhibits remarkable chemical properties that make it a valuable building block in synthetic chemistry. Its molecular formula, C7H2BrClF5N, underscores its complexity and potential for diverse applications.

The synthesis of 2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine typically involves multi-step reactions, including halogenation, fluorination, and pyridine ring functionalization. Researchers have explored its utility in developing crop protection agents, owing to its ability to act as a key intermediate in the production of pesticides and herbicides. The presence of both bromo and chloro substituents enhances its reactivity, enabling precise modifications for targeted biological activity.

In recent years, the demand for fluorinated pyridines like 2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine has surged due to their role in drug discovery. The trifluoromethyl group is particularly sought after for its ability to improve metabolic stability and bioavailability in pharmaceutical compounds. This aligns with the growing trend of fluorine incorporation in medicinal chemistry, a topic frequently searched by professionals in the field.

From an environmental perspective, the compound's degradation pathways and ecotoxicological profile are subjects of ongoing research. As sustainability becomes a priority, scientists are investigating greener synthesis methods and the biodegradability of such halogenated compounds. These aspects resonate with current industry trends and regulatory requirements, making it a hot topic in academic and industrial circles.

The physical properties of 2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine, such as its melting point, solubility, and stability, are critical for its handling and application. Analytical techniques like NMR spectroscopy and mass spectrometry are routinely employed to verify its purity and structural integrity. These details are often queried by laboratory technicians and quality control specialists.

In the realm of material science, this compound's electronic properties have sparked interest for potential use in organic electronics and catalysis. Its electron-withdrawing groups can influence charge distribution, making it a candidate for advanced materials design. This application is frequently discussed in forums and publications focused on innovative materials.

For those seeking supply chain information, 2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine is available through specialized chemical suppliers with strict quality assurance protocols. Its storage conditions and handling precautions are essential considerations, often highlighted in safety data sheets (SDS). These practical aspects are commonly searched by procurement professionals and research teams.

Looking ahead, the versatility of 2-Bromo-4-chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridine ensures its continued relevance in cutting-edge research. Whether in agrochemical innovation, pharmaceutical development, or emerging technologies, this compound exemplifies the intersection of chemical ingenuity and practical application. Its study remains a dynamic area, reflecting the evolving needs of science and industry.

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