Cas no 1805476-12-3 (5-Amino-4-bromo-2-(chloromethyl)pyridine)

5-Amino-4-bromo-2-(chloromethyl)pyridine structure
1805476-12-3 structure
Product Name:5-Amino-4-bromo-2-(chloromethyl)pyridine
CAS No:1805476-12-3
MF:C6H6BrClN2
MW:221.482239246368
CID:4898754
Update Time:2025-11-02

5-Amino-4-bromo-2-(chloromethyl)pyridine Chemical and Physical Properties

Names and Identifiers

    • 5-Amino-4-bromo-2-(chloromethyl)pyridine
    • Inchi: 1S/C6H6BrClN2/c7-5-1-4(2-8)10-3-6(5)9/h1,3H,2,9H2
    • InChI Key: QRWDDLGQRMVKEV-UHFFFAOYSA-N
    • SMILES: BrC1=CC(CCl)=NC=C1N

Computed Properties

  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 112
  • XLogP3: 1.3
  • Topological Polar Surface Area: 38.9

5-Amino-4-bromo-2-(chloromethyl)pyridine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A029016366-250mg
5-Amino-4-bromo-2-(chloromethyl)pyridine
1805476-12-3 95%
250mg
$960.40 2022-04-01
Alichem
A029016366-1g
5-Amino-4-bromo-2-(chloromethyl)pyridine
1805476-12-3 95%
1g
$3,155.55 2022-04-01

Additional information on 5-Amino-4-bromo-2-(chloromethyl)pyridine

Comprehensive Overview of 5-Amino-4-bromo-2-(chloromethyl)pyridine (CAS No. 1805476-12-3)

5-Amino-4-bromo-2-(chloromethyl)pyridine (CAS No. 1805476-12-3) is a versatile heterocyclic compound widely used in pharmaceutical and agrochemical research. Its unique molecular structure, featuring a pyridine core substituted with amino, bromo, and chloromethyl functional groups, makes it a valuable intermediate in organic synthesis. Researchers and industry professionals frequently search for "5-Amino-4-bromo-2-(chloromethyl)pyridine synthesis" or "CAS 1805476-12-3 applications," highlighting its significance in drug discovery and material science.

The compound's bromine and chloromethyl substituents enable diverse chemical transformations, such as cross-coupling reactions and nucleophilic substitutions. This reactivity aligns with current trends in sustainable chemistry, where scientists explore "green synthesis of halogenated pyridines" or "eco-friendly functionalization techniques." Its amino group further enhances its utility as a building block for biologically active molecules, addressing the growing demand for "nitrogen-containing heterocycles in drug design."

Analytical characterization of 5-Amino-4-bromo-2-(chloromethyl)pyridine typically involves advanced techniques like NMR spectroscopy, HPLC purity analysis, and mass spectrometry. Recent publications emphasize its role in developing kinase inhibitors and antimicrobial agents, responding to queries like "pyridine derivatives in medicinal chemistry." The compound's stability under controlled conditions makes it suitable for scalable production, a topic often searched as "industrial-scale pyridine manufacturing."

In material science, this compound contributes to the synthesis of functionalized polymers and coordination complexes, addressing interests in "smart materials design." Its chloromethyl group allows covalent attachment to surfaces or biomolecules, relevant to "surface modification strategies" in nanotechnology. Safety data sheets emphasize proper handling procedures, with researchers frequently seeking "5-Amino-4-bromo-2-(chloromethyl)pyridine storage guidelines."

The global market for halogenated pyridine derivatives shows steady growth, driven by pharmaceutical R&D and specialty chemicals. Patent analyses reveal increasing applications in "crop protection agents" and "electronic materials," correlating with search trends like "CAS 1805476-12-3 suppliers." Regulatory compliance remains a key consideration, with databases documenting its REACH registration status and transport classification.

Future research directions may explore its potential in "photocatalysis" or "bioconjugation chemistry," areas gaining traction in scientific literature. The compound's balanced lipophilicity and reactivity profile position it as a focus for "fragment-based drug discovery" methodologies. Analytical challenges, such as "trace impurity profiling in pyridine derivatives," continue to drive methodological innovations in quality control.

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