Cas no 1805401-37-9 (2-Chloro-3-cyano-6-(difluoromethyl)-4-methylpyridine)
2-Chloro-3-cyano-6-(difluoromethyl)-4-methylpyridine is a versatile pyridine derivative with significant applications in agrochemical and pharmaceutical synthesis. Its molecular structure, featuring chloro, cyano, and difluoromethyl substituents, enhances reactivity and selectivity in cross-coupling reactions, making it a valuable intermediate for constructing complex heterocyclic compounds. The presence of the difluoromethyl group improves metabolic stability and bioavailability, while the chloro and cyano groups offer multiple functionalization sites for further derivatization. This compound exhibits excellent thermal stability and solubility in common organic solvents, facilitating its use in diverse synthetic pathways. Its high purity and well-defined structure ensure reproducibility in research and industrial applications, particularly in the development of advanced crop protection agents and bioactive molecules.
1805401-37-9 structure
Product Name:2-Chloro-3-cyano-6-(difluoromethyl)-4-methylpyridine
CAS No:1805401-37-9
MF:C8H5ClF2N2
MW:202.588507413864
CID:4865052
Update Time:2025-07-02
2-Chloro-3-cyano-6-(difluoromethyl)-4-methylpyridine Chemical and Physical Properties
Names and Identifiers
-
- 2-Chloro-3-cyano-6-(difluoromethyl)-4-methylpyridine
-
- Inchi: 1S/C8H5ClF2N2/c1-4-2-6(8(10)11)13-7(9)5(4)3-12/h2,8H,1H3
- InChI Key: HFXWIUWQEVFVEZ-UHFFFAOYSA-N
- SMILES: ClC1=C(C#N)C(C)=CC(C(F)F)=N1
Computed Properties
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 13
- Rotatable Bond Count: 1
- Complexity: 225
- XLogP3: 2.6
- Topological Polar Surface Area: 36.7
2-Chloro-3-cyano-6-(difluoromethyl)-4-methylpyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029055453-1g |
2-Chloro-3-cyano-6-(difluoromethyl)-4-methylpyridine |
1805401-37-9 | 97% | 1g |
$1,534.70 | 2022-04-01 |
2-Chloro-3-cyano-6-(difluoromethyl)-4-methylpyridine Related Literature
-
Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
-
Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
-
Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
-
Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
1805401-37-9 (2-Chloro-3-cyano-6-(difluoromethyl)-4-methylpyridine) Related Products
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
- 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
- 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
- 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)
Recommended suppliers
Hubei Cuiyuan Biotechnology Co.,Ltd
Gold Member
CN Supplier
Reagent
Beyond Pharmaceutical Co., Ltd
Gold Member
CN Supplier
Reagent
SHOCHEM(SHANGHAI) CO.,lTD
Gold Member
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
CN Supplier
Bulk
Suzhou Genelee Bio-Technology Co., Ltd.
Gold Member
CN Supplier
Bulk