Cas no 1805311-74-3 (2-(Difluoromethyl)-4-methyl-5-nitropyridine)
2-(Difluoromethyl)-4-methyl-5-nitropyridine is a fluorinated nitropyridine derivative with applications in pharmaceutical and agrochemical research. Its key structural features—a difluoromethyl group at the 2-position and a nitro substituent at the 5-position—impart unique reactivity, making it a valuable intermediate for synthesizing bioactive compounds. The difluoromethyl group enhances metabolic stability and lipophilicity, while the nitro functionality offers versatility for further functionalization via reduction or nucleophilic substitution. This compound is particularly useful in the development of fluorinated heterocycles, where its well-defined regiochemistry and stability under synthetic conditions are advantageous. High purity and consistent quality ensure reliable performance in complex organic transformations.
1805311-74-3 structure
Product Name:2-(Difluoromethyl)-4-methyl-5-nitropyridine
CAS No:1805311-74-3
MF:C7H6F2N2O2
MW:188.131548404694
MDL:MFCD25482424
CID:4782060
PubChem ID:118837357
Update Time:2026-02-27
2-(Difluoromethyl)-4-methyl-5-nitropyridine Chemical and Physical Properties
Names and Identifiers
-
- 2-(Difluoromethyl)-4-methyl-5-nitropyridine
- MFCD25482424
- 1805311-74-3
- D80141
-
- MDL: MFCD25482424
- Inchi: 1S/C7H6F2N2O2/c1-4-2-5(7(8)9)10-3-6(4)11(12)13/h2-3,7H,1H3
- InChI Key: PFOPZYWMFMQDKO-UHFFFAOYSA-N
- SMILES: FC(C1C=C(C)C(=CN=1)[N+](=O)[O-])F
Computed Properties
- Exact Mass: 188.03973376g/mol
- Monoisotopic Mass: 188.03973376g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 13
- Rotatable Bond Count: 1
- Complexity: 195
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.7
- Topological Polar Surface Area: 58.7
2-(Difluoromethyl)-4-methyl-5-nitropyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029075001-250mg |
2-(Difluoromethyl)-4-methyl-5-nitropyridine |
1805311-74-3 | 97% | 250mg |
$504.00 | 2022-04-01 | |
| Alichem | A029075001-500mg |
2-(Difluoromethyl)-4-methyl-5-nitropyridine |
1805311-74-3 | 97% | 500mg |
$847.60 | 2022-04-01 | |
| Alichem | A029075001-1g |
2-(Difluoromethyl)-4-methyl-5-nitropyridine |
1805311-74-3 | 97% | 1g |
$1,549.60 | 2022-04-01 | |
| Matrix Scientific | 219985-500mg |
2-(Difluoromethyl)-4-methyl-5-nitropyridine, 95% min |
1805311-74-3 | 95% | 500mg |
$1156.00 | 2023-09-06 | |
| Matrix Scientific | 219985-1g |
2-(Difluoromethyl)-4-methyl-5-nitropyridine, 95% min |
1805311-74-3 | 95% | 1g |
$1890.00 | 2023-09-06 | |
| Ambeed | A782601-100mg |
2-(Difluoromethyl)-4-methyl-5-nitropyridine |
1805311-74-3 | 95% | 100mg |
$296.0 | 2025-02-26 | |
| Ambeed | A782601-250mg |
2-(Difluoromethyl)-4-methyl-5-nitropyridine |
1805311-74-3 | 95% | 250mg |
$503.0 | 2025-02-26 | |
| Ambeed | A782601-1g |
2-(Difluoromethyl)-4-methyl-5-nitropyridine |
1805311-74-3 | 95% | 1g |
$1359.0 | 2025-02-26 | |
| 1PlusChem | 1P021PDO-100mg |
2-(DIFLUOROMETHYL)-4-METHYL-5-NITROPYRIDINE |
1805311-74-3 | 95% | 100mg |
$296.00 | 2024-06-18 | |
| 1PlusChem | 1P021PDO-250mg |
2-(DIFLUOROMETHYL)-4-METHYL-5-NITROPYRIDINE |
1805311-74-3 | 95% | 250mg |
$519.00 | 2024-06-18 |
2-(Difluoromethyl)-4-methyl-5-nitropyridine Related Literature
-
Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
-
Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
-
Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
-
Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
-
5. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
1805311-74-3 (2-(Difluoromethyl)-4-methyl-5-nitropyridine) Related Products
- 1805325-67-0(4-(Difluoromethyl)-2-(fluoromethyl)-5-nitropyridine)
- 1805318-45-9(4-Cyano-2-(difluoromethyl)-5-nitropyridine)
- 1805312-10-0(4-(Difluoromethyl)-2-methyl-3-nitropyridine)
- 1804718-64-6(2-(Difluoromethyl)-4-(fluoromethyl)-5-nitropyridine)
- 1805925-80-7(2-(Difluoromethyl)-5-nitropyridine-4-carboxaldehyde)
- 1805325-50-1(2-(Difluoromethyl)-4-(fluoromethyl)-3-nitropyridine)
- 1805309-78-7(2-(Difluoromethyl)-4-methyl-3-nitropyridine)
- 1804694-29-8(2-(Difluoromethyl)-3-nitro-4-(trifluoromethyl)pyridine)
- 944317-53-7(2-(Trifluoromethyl)-4-methyl-5-nitropyridine)
- 1803693-53-9(2-(Difluoromethyl)-5-nitro-4-(trifluoromethyl)pyridine)
Recommended suppliers
Zouping Mingyuan Import and Export Trading Co., Ltd
Gold Member
CN Supplier
Reagent
TAIXING JOXIN BIO-TEC CO.,LTD.
Gold Member
CN Supplier
Bulk
PRIBOLAB PTE.LTD
Gold Member
CN Supplier
Reagent
Zhejiang Brunova Technology Co., Ltd.
Gold Member
CN Supplier
Bulk
Yunnanjiuzhen
Gold Member
CN Supplier
Bulk