Cas no 1805252-62-3 (3,4-Diamino-2-(difluoromethyl)pyridine)
3,4-Diamino-2-(difluoromethyl)pyridine is a fluorinated pyridine derivative with a reactive diamine functionality, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The presence of both amino groups at the 3- and 4-positions allows for selective functionalization, enabling the construction of heterocyclic scaffolds. The difluoromethyl group at the 2-position enhances metabolic stability and influences electronic properties, which can be advantageous in drug design. This compound is particularly useful in the development of kinase inhibitors and other bioactive molecules. Its well-defined structure and high purity ensure consistent performance in synthetic applications, offering researchers a reliable building block for complex molecular architectures.
1805252-62-3 structure
Product Name:3,4-Diamino-2-(difluoromethyl)pyridine
CAS No:1805252-62-3
MF:C6H7F2N3
MW:159.136687517166
CID:4845812
Update Time:2025-06-10
3,4-Diamino-2-(difluoromethyl)pyridine Chemical and Physical Properties
Names and Identifiers
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- 3,4-Diamino-2-(difluoromethyl)pyridine
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- Inchi: 1S/C6H7F2N3/c7-6(8)5-4(10)3(9)1-2-11-5/h1-2,6H,10H2,(H2,9,11)
- InChI Key: ZTHMLVVXGQGFNN-UHFFFAOYSA-N
- SMILES: FC(C1C(=C(C=CN=1)N)N)F
Computed Properties
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 131
- XLogP3: 0.1
- Topological Polar Surface Area: 64.9
3,4-Diamino-2-(difluoromethyl)pyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029078894-250mg |
3,4-Diamino-2-(difluoromethyl)pyridine |
1805252-62-3 | 97% | 250mg |
$475.20 | 2022-04-01 | |
| Alichem | A029078894-500mg |
3,4-Diamino-2-(difluoromethyl)pyridine |
1805252-62-3 | 97% | 500mg |
$831.30 | 2022-04-01 | |
| Alichem | A029078894-1g |
3,4-Diamino-2-(difluoromethyl)pyridine |
1805252-62-3 | 97% | 1g |
$1,549.60 | 2022-04-01 |
3,4-Diamino-2-(difluoromethyl)pyridine Related Literature
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Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
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Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
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Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651
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Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
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Jason Wan Lab Chip, 2020,20, 4528-4538
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