Cas no 1805016-04-9 (3-Amino-2-(difluoromethyl)-6-methyl-4-(trifluoromethyl)pyridine)
3-Amino-2-(difluoromethyl)-6-methyl-4-(trifluoromethyl)pyridine is a fluorinated pyridine derivative with a unique structural profile, featuring both difluoromethyl and trifluoromethyl substituents. Its electron-deficient aromatic system and reactive amino group make it a valuable intermediate in agrochemical and pharmaceutical synthesis, particularly for developing compounds with enhanced bioactivity and metabolic stability. The presence of multiple fluorine atoms contributes to improved lipophilicity and resistance to oxidative degradation. This compound is particularly useful in the design of heterocyclic scaffolds for crop protection agents and small-molecule therapeutics, where selective functionalization is required. High purity grades are available for precision applications in research and industrial settings.
1805016-04-9 structure
Product Name:3-Amino-2-(difluoromethyl)-6-methyl-4-(trifluoromethyl)pyridine
CAS No:1805016-04-9
MF:C8H7F5N2
MW:226.146599054337
CID:4810561
Update Time:2025-10-29
3-Amino-2-(difluoromethyl)-6-methyl-4-(trifluoromethyl)pyridine Chemical and Physical Properties
Names and Identifiers
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- 3-Amino-2-(difluoromethyl)-6-methyl-4-(trifluoromethyl)pyridine
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- Inchi: 1S/C8H7F5N2/c1-3-2-4(8(11,12)13)5(14)6(15-3)7(9)10/h2,7H,14H2,1H3
- InChI Key: KGZFGGQESZSFJW-UHFFFAOYSA-N
- SMILES: FC(C1C=C(C)N=C(C(F)F)C=1N)(F)F
Computed Properties
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 7
- Heavy Atom Count: 15
- Rotatable Bond Count: 1
- Complexity: 218
- XLogP3: 2.1
- Topological Polar Surface Area: 38.9
3-Amino-2-(difluoromethyl)-6-methyl-4-(trifluoromethyl)pyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029065555-1g |
3-Amino-2-(difluoromethyl)-6-methyl-4-(trifluoromethyl)pyridine |
1805016-04-9 | 97% | 1g |
$1,460.20 | 2022-04-01 |
3-Amino-2-(difluoromethyl)-6-methyl-4-(trifluoromethyl)pyridine Related Literature
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Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
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Quan Xiang,Yiqin Chen,Zhiqin Li,Kaixi Bi,Guanhua Zhang,Huigao Duan Nanoscale, 2016,8, 19541-19550
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Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
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