Cas no 1804848-55-2 (2-Bromo-4-methoxy-5-(trifluoromethoxy)aniline)

2-Bromo-4-methoxy-5-(trifluoromethoxy)aniline is a halogenated aniline derivative featuring bromo, methoxy, and trifluoromethoxy substituents on the aromatic ring. This compound is primarily utilized as a versatile intermediate in pharmaceutical and agrochemical synthesis, where its electron-withdrawing and electron-donating groups enable selective functionalization. The presence of both bromine and trifluoromethoxy groups enhances its reactivity in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, facilitating the construction of complex heterocyclic scaffolds. Its stability under standard conditions and compatibility with diverse reaction conditions make it a valuable building block for medicinal chemistry and material science applications. The compound is typically handled under inert conditions to preserve its amine functionality.
2-Bromo-4-methoxy-5-(trifluoromethoxy)aniline structure
1804848-55-2 structure
Product Name:2-Bromo-4-methoxy-5-(trifluoromethoxy)aniline
CAS No:1804848-55-2
MF:C8H7BrF3NO2
MW:286.045892000198
CID:4974150
Update Time:2025-05-27

2-Bromo-4-methoxy-5-(trifluoromethoxy)aniline Chemical and Physical Properties

Names and Identifiers

    • BrC1=C(N)C=C(C(=C1)OC)OC(F)(F)F
    • 2-Bromo-4-methoxy-5-(trifluoromethoxy)aniline
    • Inchi: 1S/C8H7BrF3NO2/c1-14-6-2-4(9)5(13)3-7(6)15-8(10,11)12/h2-3H,13H2,1H3
    • InChI Key: FERVQOJSXHQSBS-UHFFFAOYSA-N
    • SMILES: BrC1=CC(=C(C=C1N)OC(F)(F)F)OC

Computed Properties

  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 2
  • Complexity: 215
  • XLogP3: 3.1
  • Topological Polar Surface Area: 44.5

2-Bromo-4-methoxy-5-(trifluoromethoxy)aniline Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A013020605-250mg
2-Bromo-4-methoxy-5-(trifluoromethoxy)aniline
1804848-55-2 97%
250mg
475.20 USD 2021-06-24
Alichem
A013020605-500mg
2-Bromo-4-methoxy-5-(trifluoromethoxy)aniline
1804848-55-2 97%
500mg
815.00 USD 2021-06-24
Alichem
A013020605-1g
2-Bromo-4-methoxy-5-(trifluoromethoxy)aniline
1804848-55-2 97%
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1,445.30 USD 2021-06-24
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