Cas no 1804670-29-8 (5-Bromo-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-methanol)
5-Bromo-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-methanol is a fluorinated pyridine derivative with significant utility in pharmaceutical and agrochemical research. Its key structural features—a bromo substituent, difluoromethyl, and trifluoromethyl groups—enhance its reactivity and selectivity, making it a valuable intermediate in the synthesis of bioactive compounds. The presence of multiple fluorine atoms improves metabolic stability and lipophilicity, which are advantageous in drug design. The hydroxymethyl group at the 2-position offers further functionalization potential, enabling diverse derivatization pathways. This compound’s well-defined structure and high purity make it suitable for precision applications in medicinal chemistry and material science.
1804670-29-8 structure
Product Name:5-Bromo-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-methanol
CAS No:1804670-29-8
MF:C8H5BrF5NO
MW:306.027418851852
CID:4809091
Update Time:2025-05-28
5-Bromo-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-methanol Chemical and Physical Properties
Names and Identifiers
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- 5-Bromo-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-methanol
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- Inchi: 1S/C8H5BrF5NO/c9-3-1-15-4(2-16)6(8(12,13)14)5(3)7(10)11/h1,7,16H,2H2
- InChI Key: NHFUWEGQJNUDEC-UHFFFAOYSA-N
- SMILES: BrC1=CN=C(CO)C(C(F)(F)F)=C1C(F)F
Computed Properties
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 7
- Heavy Atom Count: 16
- Rotatable Bond Count: 2
- Complexity: 237
- XLogP3: 2.2
- Topological Polar Surface Area: 33.1
5-Bromo-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-methanol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029055526-1g |
5-Bromo-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-methanol |
1804670-29-8 | 97% | 1g |
$1,445.30 | 2022-04-01 |
5-Bromo-4-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-methanol Related Literature
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Teresita Carrillo-Hernández,Philippe Schaeffer,Pierre Albrecht Chem. Commun., 2001, 1976-1977
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Huiying Xu,Lu Zheng,Yu Zhou,Bang-Ce Ye Analyst, 2021,146, 5542-5549
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Jingquan Liu,Huiyun Liu,Zhongfan Jia,Volga Bulmus,Thomas P. Davis Chem. Commun., 2008, 6582-6584
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4. An amorphous lanthanum–iridium solid solution with an open structure for efficient water splitting?Wei Sun,Chenglong Ma,Xinlong Tian,Jianjun Liao,Ji Yang,Chengjun Ge,Weiwei Huang J. Mater. Chem. A, 2020,8, 12518-12525
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Hyejin Moon,Aaron R. Wheeler,Robin L. Garrell,Chang-Jin “CJ” Kim Lab Chip, 2006,6, 1213-1219
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