Cas no 1804151-26-5 (5-Bromo-2-chloro-6-difluoromethoxy-1H-benzimidazole)
5-Bromo-2-chloro-6-difluoromethoxy-1H-benzimidazole is a halogenated benzimidazole derivative with a difluoromethoxy substituent, offering unique reactivity and structural properties for pharmaceutical and agrochemical applications. Its bromo and chloro groups enhance electrophilic substitution potential, while the difluoromethoxy moiety improves metabolic stability and lipophilicity. This compound serves as a versatile intermediate in the synthesis of bioactive molecules, particularly in the development of kinase inhibitors and antimicrobial agents. The presence of multiple halogens allows for selective functionalization, making it valuable for structure-activity relationship studies. Its high purity and well-defined structure ensure reproducibility in research and industrial processes.
1804151-26-5 structure
Product Name:5-Bromo-2-chloro-6-difluoromethoxy-1H-benzimidazole
CAS No:1804151-26-5
MF:C8H4BrClF2N2O
MW:297.483966827393
CID:4824480
Update Time:2025-10-29
5-Bromo-2-chloro-6-difluoromethoxy-1H-benzimidazole Chemical and Physical Properties
Names and Identifiers
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- 5-Bromo-2-chloro-6-difluoromethoxy-1H-benzimidazole
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- Inchi: 1S/C8H4BrClF2N2O/c9-3-1-4-5(14-7(10)13-4)2-6(3)15-8(11)12/h1-2,8H,(H,13,14)
- InChI Key: PQZUTDSHMSKMOK-UHFFFAOYSA-N
- SMILES: BrC1=CC2=C(C=C1OC(F)F)N=C(N2)Cl
Computed Properties
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 15
- Rotatable Bond Count: 2
- Complexity: 237
- XLogP3: 4.1
- Topological Polar Surface Area: 37.9
5-Bromo-2-chloro-6-difluoromethoxy-1H-benzimidazole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A061006365-250mg |
5-Bromo-2-chloro-6-difluoromethoxy-1H-benzimidazole |
1804151-26-5 | 98% | 250mg |
$923.57 | 2022-04-02 | |
| Alichem | A061006365-500mg |
5-Bromo-2-chloro-6-difluoromethoxy-1H-benzimidazole |
1804151-26-5 | 98% | 500mg |
$1,181.75 | 2022-04-02 | |
| Alichem | A061006365-1g |
5-Bromo-2-chloro-6-difluoromethoxy-1H-benzimidazole |
1804151-26-5 | 98% | 1g |
$2,181.61 | 2022-04-02 |
5-Bromo-2-chloro-6-difluoromethoxy-1H-benzimidazole Related Literature
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1. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
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2. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imagingGhazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683
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Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
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Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
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