Cas no 1803894-98-5 (6-Bromo-5-hydroxymethyl-1H-benzimidazole)
6-Bromo-5-hydroxymethyl-1H-benzimidazole is a benzimidazole derivative with a bromo substituent at the 6-position and a hydroxymethyl group at the 5-position. This compound serves as a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its reactive functional groups allow for further derivatization, making it valuable for constructing complex heterocyclic frameworks. The hydroxymethyl group offers a handle for additional modifications, while the bromo substituent facilitates cross-coupling reactions. This compound is of interest in medicinal chemistry due to the benzimidazole core's prevalence in bioactive molecules. It is typically handled under controlled conditions due to its sensitivity.
1803894-98-5 structure
Product Name:6-Bromo-5-hydroxymethyl-1H-benzimidazole
CAS No:1803894-98-5
MF:C8H7BrN2O
MW:227.057980775833
CID:4825864
Update Time:2025-10-16
6-Bromo-5-hydroxymethyl-1H-benzimidazole Chemical and Physical Properties
Names and Identifiers
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- 6-Bromo-5-hydroxymethyl-1H-benzimidazole
- (5-bromo-1H-benzo[d]imidazol-6-yl)methanol
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- Inchi: 1S/C8H7BrN2O/c9-6-2-8-7(10-4-11-8)1-5(6)3-12/h1-2,4,12H,3H2,(H,10,11)
- InChI Key: SYEDHBFAOHFLEF-UHFFFAOYSA-N
- SMILES: BrC1=CC2=C(C=C1CO)NC=N2
Computed Properties
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 12
- Rotatable Bond Count: 1
- Complexity: 167
- XLogP3: 1.3
- Topological Polar Surface Area: 48.9
6-Bromo-5-hydroxymethyl-1H-benzimidazole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A061002021-250mg |
6-Bromo-5-hydroxymethyl-1H-benzimidazole |
1803894-98-5 | 98% | 250mg |
$702.85 | 2022-04-02 | |
| Alichem | A061002021-500mg |
6-Bromo-5-hydroxymethyl-1H-benzimidazole |
1803894-98-5 | 98% | 500mg |
$1,055.58 | 2022-04-02 | |
| Alichem | A061002021-1g |
6-Bromo-5-hydroxymethyl-1H-benzimidazole |
1803894-98-5 | 98% | 1g |
$1,900.95 | 2022-04-02 |
6-Bromo-5-hydroxymethyl-1H-benzimidazole Related Literature
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Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
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Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
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Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
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Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
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