Cas no 1803591-15-2 (2-Cyclopropyl-5-fluoropyridine)
2-Cyclopropyl-5-fluoropyridine is a fluorinated pyridine derivative featuring a cyclopropyl substituent at the 2-position. This compound is valued for its structural versatility in pharmaceutical and agrochemical synthesis, where the cyclopropyl group enhances steric and electronic properties, while the fluorine atom improves metabolic stability and bioavailability. Its rigid framework makes it a useful intermediate for designing bioactive molecules, particularly in the development of kinase inhibitors and antimicrobial agents. The compound exhibits favorable reactivity in cross-coupling and functionalization reactions, enabling precise modifications. High purity and consistent quality ensure reliable performance in research and industrial applications.
1803591-15-2 structure
Product Name:2-Cyclopropyl-5-fluoropyridine
CAS No:1803591-15-2
MF:C8H8FN
MW:137.154225349426
MDL:MFCD28968215
CID:4616807
PubChem ID:89225840
Update Time:2025-06-07
2-Cyclopropyl-5-fluoropyridine Chemical and Physical Properties
Names and Identifiers
-
- 2-Cyclopropyl-5-fluoropyridine
- SY203733
-
- MDL: MFCD28968215
- Inchi: 1S/C8H8FN/c9-7-3-4-8(10-5-7)6-1-2-6/h3-6H,1-2H2
- InChI Key: LNYWOMUBLSZIPG-UHFFFAOYSA-N
- SMILES: FC1=CN=C(C=C1)C1CC1
Computed Properties
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 10
- Rotatable Bond Count: 1
- Complexity: 122
- XLogP3: 1.5
- Topological Polar Surface Area: 12.9
2-Cyclopropyl-5-fluoropyridine Security Information
- Signal Word:warning
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement: P264+P280+P305+P351+P338+P337+P313
- Safety Instruction: H303+H313+H333
- Storage Condition:storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
2-Cyclopropyl-5-fluoropyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| eNovation Chemicals LLC | D777787-1g |
2-Cyclopropyl-5-fluoropyridine |
1803591-15-2 | 95% | 1g |
$715 | 2024-07-20 | |
| Alichem | A029197515-1g |
2-Cyclopropyl-5-fluoropyridine |
1803591-15-2 | 95% | 1g |
$837.29 | 2022-04-02 | |
| TRC | B425918-10mg |
2-cyclopropyl-5-fluoropyridine |
1803591-15-2 | 10mg |
$ 70.00 | 2022-06-07 | ||
| TRC | B425918-50mg |
2-cyclopropyl-5-fluoropyridine |
1803591-15-2 | 50mg |
$ 230.00 | 2022-06-07 | ||
| TRC | B425918-100mg |
2-cyclopropyl-5-fluoropyridine |
1803591-15-2 | 100mg |
$ 340.00 | 2022-06-07 | ||
| Enamine | EN300-221311-0.05g |
2-cyclopropyl-5-fluoropyridine |
1803591-15-2 | 95% | 0.05g |
$206.0 | 2023-09-16 | |
| Enamine | EN300-221311-0.1g |
2-cyclopropyl-5-fluoropyridine |
1803591-15-2 | 95% | 0.1g |
$307.0 | 2023-09-16 | |
| Enamine | EN300-221311-0.25g |
2-cyclopropyl-5-fluoropyridine |
1803591-15-2 | 95% | 0.25g |
$438.0 | 2023-09-16 | |
| Enamine | EN300-221311-0.5g |
2-cyclopropyl-5-fluoropyridine |
1803591-15-2 | 95% | 0.5g |
$691.0 | 2023-09-16 | |
| Enamine | EN300-221311-1.0g |
2-cyclopropyl-5-fluoropyridine |
1803591-15-2 | 95% | 1g |
$0.0 | 2023-06-08 |
2-Cyclopropyl-5-fluoropyridine Related Literature
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Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
-
Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
-
David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
-
Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
-
Qiao Song,Angela Bamesberger,Lingyun Yang,Haley Houtwed,Haishi Cao Analyst, 2014,139, 3588-3592
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