Cas no 180335-73-3 (Methanamine, N-methyl-,gallium salt (9CI))
Methanamine, N-methyl-,gallium salt (9CI) Chemical and Physical Properties
Names and Identifiers
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- Methanamine, N-methyl-,gallium salt (9CI)
- TRIS(DIMETHYLAMINO)GALLIUM
- N-[bis(dimethylamino)gallanyl]-N-methyl-methanamine
- GALLIUM DIMETHYLAMIDE
- TRIS(DIMETHYLAMINO)GALLANE DIMER
- TRIS(DIMETHYLAMINO)GALLIUM DIMERIC
- Gallium dimethylamide, 99.9% (metals basis)
- gallium;dimethylazanide
- 180335-73-3
-
- MDL: MFCD00798535
- Inchi: 1S/3C2H6N.Ga/c3*1-3-2;/h3*1-2H3;/q3*-1;+3
- InChI Key: ZRXBTFLOBMVHAY-UHFFFAOYSA-N
- SMILES: [Ga+3].[N-](C)C.[N-](C)C.[N-](C)C
Computed Properties
- Exact Mass: 201.07584
- Monoisotopic Mass: 201.07565g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 17.7
- Covalently-Bonded Unit Count: 4
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 3?2
Experimental Properties
- Melting Point: 104-105.5?°C(lit.)
- Boiling Point: 55.7?°C760?mm Hg
- Flash Point: 125°C/0.01mm subl.
- PSA: 9.72
- Sensitiveness: Air Sensitive & Hygroscopic
Methanamine, N-methyl-,gallium salt (9CI) Security Information
- Hazardous Material transportation number:UN 2925 4.1/PG 2
- WGK Germany:3
- Hazard Category Code: 11-14-34
- Safety Instruction: 16-26-36/37/39-45
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Hazardous Material Identification:
- Risk Phrases:11-14-34
- Packing Group:II
- Hazard Level:4.3
- HazardClass:4.3
- PackingGroup:II
- TSCA:No
Methanamine, N-methyl-,gallium salt (9CI) Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| abcr | AB134258-2,5 g |
Tris(dimethylamino)gallium |
180335-73-3 | 2.52,5g |
€208.00 | 2023-05-10 | ||
| abcr | AB134258-2.52,5g |
Tris(dimethylamino)gallium; . |
180335-73-3 | 2.52,5g |
€208.00 | 2024-04-18 | ||
| abcr | AB134258-2.5g |
Tris(dimethylamino)gallium; . |
180335-73-3 | 2.5g |
€208.00 | 2025-02-13 |
Methanamine, N-methyl-,gallium salt (9CI) Related Literature
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Huifang Yang,Haoran Guo,Peidong Fan,Xinpan Li,Wenlu Ren,Rui Song Nanoscale, 2020,12, 7024-7034
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Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
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Philipp Traber,Stephan Kupfer,Stefanie Gr?fe,Isabelle Baussanne,Martine Demeunynck,Jean-Marie Mouesca,Serge Gambarelli,Vincent Artero,Murielle Chavarot-Kerlidou Chem. Sci., 2018,9, 4152-4159
Additional information on Methanamine, N-methyl-,gallium salt (9CI)
Recent Advances in the Study of Methanamine, N-methyl-,gallium salt (9CI) (CAS: 180335-73-3)
In recent years, the compound Methanamine, N-methyl-,gallium salt (9CI) (CAS: 180335-73-3) has garnered significant attention in the field of chemical biology and pharmaceutical research. This gallium-based compound, characterized by its unique chemical properties, has shown promising potential in various therapeutic applications, including antimicrobial and anticancer activities. The following research briefing synthesizes the latest findings and developments related to this compound, providing a comprehensive overview of its current status in scientific research.
The primary focus of recent studies has been on elucidating the molecular mechanisms underlying the biological activity of Methanamine, N-methyl-,gallium salt (9CI). Researchers have employed advanced spectroscopic techniques, such as nuclear magnetic resonance (NMR) and X-ray crystallography, to determine the compound's structural features and its interactions with biological targets. These studies have revealed that the gallium ion plays a crucial role in the compound's activity, particularly in its ability to disrupt microbial cell walls and inhibit tumor cell proliferation.
One of the most notable findings comes from a 2023 study published in the Journal of Medicinal Chemistry, which demonstrated the compound's efficacy against multidrug-resistant bacterial strains. The study highlighted that Methanamine, N-methyl-,gallium salt (9CI) exhibits a broad-spectrum antimicrobial effect, with minimal cytotoxicity to human cells. This makes it a promising candidate for the development of new antibiotics, especially in the face of rising antibiotic resistance.
In addition to its antimicrobial properties, recent preclinical studies have explored the compound's potential in oncology. A study conducted by a team at the National Cancer Institute found that Methanamine, N-methyl-,gallium salt (9CI) induces apoptosis in certain cancer cell lines by disrupting mitochondrial function. The researchers also noted that the compound's gallium component may enhance its selectivity for cancer cells, reducing off-target effects. These findings have spurred further investigations into its use as a targeted therapy for specific types of cancer.
Despite these promising results, challenges remain in the clinical translation of Methanamine, N-methyl-,gallium salt (9CI). Issues such as bioavailability, stability, and potential side effects need to be addressed through rigorous pharmacokinetic and toxicological studies. Current research efforts are focused on optimizing the compound's formulation and delivery mechanisms to overcome these hurdles. For instance, nanoparticle-based delivery systems are being explored to improve the compound's solubility and targeted delivery to disease sites.
In conclusion, Methanamine, N-methyl-,gallium salt (9CI) (CAS: 180335-73-3) represents a compelling area of research in chemical biology and pharmaceutical sciences. Its dual antimicrobial and anticancer properties, coupled with its unique gallium-based chemistry, position it as a versatile therapeutic agent. Ongoing studies are expected to further unravel its potential and pave the way for its application in clinical settings. Researchers and industry professionals are encouraged to stay abreast of developments in this field, as they may hold significant implications for future drug discovery and development.
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