Cas no 17874-76-9 (6-(methoxycarbonyl)pyridine-3-carboxylic acid)

6-(Methoxycarbonyl)pyridine-3-carboxylic acid is a versatile pyridine-based carboxylic acid derivative, commonly employed as a key intermediate in organic synthesis and pharmaceutical research. Its bifunctional structure, featuring both a methoxycarbonyl group and a carboxylic acid moiety, allows for selective modifications, making it valuable in the preparation of heterocyclic compounds, ligands, and active pharmaceutical ingredients (APIs). The compound exhibits good stability under standard conditions and is compatible with a range of coupling and condensation reactions. Its high purity and well-defined reactivity profile make it particularly useful in medicinal chemistry for the development of novel drug candidates and fine chemical applications.
6-(methoxycarbonyl)pyridine-3-carboxylic acid structure
17874-76-9 structure
Product Name:6-(methoxycarbonyl)pyridine-3-carboxylic acid
CAS No:17874-76-9
MF:C8H7NO4
MW:181.145482301712
MDL:MFCD09702182
CID:122610
PubChem ID:579631
Update Time:2025-11-02

6-(methoxycarbonyl)pyridine-3-carboxylic acid Chemical and Physical Properties

Names and Identifiers

    • 6-(Methoxycarbonyl)nicotinic acid
    • 2,5-Pyridinedicarboxylicacid, 2-methyl ester
    • 6-methoxycarbonylpyridine-3-carboxylic acid
    • 2-carbomethoxypyridine-5-carboxylic acid
    • 2-methoxycarbonylpyridine-5-carboxylic acid
    • 2-Methyl hydrogen pyridine-2,5-dicarboxylate
    • 5-carboxy-2-methoxycarbonyl-pyridine
    • 6-(methoxycarbonyl)pyridine-3-carboxylic acid
    • 6-carbomethoxynicotinic acid
    • pyridine-2,5-dicarboxylic acid 2-monomethyl ester
    • pyridine-2,5-dicarboxylic acid-2-methyl ester
    • Z254336720
    • A852665
    • 17874-76-9
    • AM803380
    • DTXSID00342194
    • AS-5310
    • SY042880
    • FT-0762523
    • 6-(Methoxycarbonyl)nicotinicacid
    • 2-METHYL HYDROGEN PYRIDINE-2.5-DICARBOXYLATE
    • 2,5-Pyridinedicarboxylic acid, 2-methyl ester
    • 6-(Methoxycarbonyl)nicotinic acid;6-Methoxycarbonylpyridine-3-carboxylic acid
    • SCHEMBL64024
    • 2,5-pyridine dicarboxylic acid methyl ester
    • EN300-28258
    • 6-(Methoxycarbonyl)nicotinic acid #
    • 6-(Methoxycarbonyl)nicotinic acid;6-(Methoxycarbonyl)pyridine-3-carboxylic Acid
    • Pyridine 2,5-dicarboxylic acid 2-methyl ester
    • MFCD09702182
    • 2-methyl hydrogen pyridine-2,5-dicarboxylate, AldrichCPR
    • SB53716
    • CS-0035737
    • BCP32325
    • AKOS005135893
    • DB-065233
    • MDL： MFCD09702182
    • Inchi： 1S/C8H7NO4/c1-13-8(12)6-3-2-5(4-9-6)7(10)11/h2-4H,1H3,(H,10,11)
    • InChI Key： QRSXLMSDECGEOU-UHFFFAOYSA-N
    • SMILES： O(C)C(C1C=CC(C(=O)O)=CN=1)=O

Computed Properties

  • Exact Mass: 181.03800
  • Monoisotopic Mass: 181.03750770 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 216
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 181.15
  • XLogP3: 0.6
  • Topological Polar Surface Area: 76.5?2

Experimental Properties

  • Color/Form: No data avaiable
  • Density: 1.4±0.1 g/cm3
  • Melting Point: No data available
  • Boiling Point: 383.8℃ at 760 mmHg
  • Flash Point: 185.9±23.7 °C
  • Refractive Index: 1.56
  • PSA: 76.49000
  • LogP: 0.56640
  • Vapor Pressure: 0.0±0.9 mmHg at 25°C

6-(methoxycarbonyl)pyridine-3-carboxylic acid Security Information

6-(methoxycarbonyl)pyridine-3-carboxylic acid Customs Data

  • HS CODE：2933399090
  • Customs Data：

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

6-(methoxycarbonyl)pyridine-3-carboxylic acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Fluorochem
066880-1g
6-(Methoxycarbonyl)nicotinic acid
 17874-76-9 97%
1g
 ￡90.00 2022-03-01
Fluorochem
066880-5g
6-(Methoxycarbonyl)nicotinic acid
 17874-76-9 97%
5g
 ￡332.00 2022-03-01
Fluorochem
066880-25g
6-(Methoxycarbonyl)nicotinic acid
 17874-76-9 97%
25g
 ￡1213.00 2022-03-01
Apollo Scientific
OR300619-1g
6-(Methoxycarbonyl)nicotinic acid
 17874-76-9
1g
 ￡55.00 2025-02-19
Apollo Scientific
OR300619-5g
6-(Methoxycarbonyl)nicotinic acid
 17874-76-9
5g
 ￡200.00 2025-02-19
ChemScence
CS-0035737-250mg
6-methoxycarbonylpyridine-3-carboxylic acid
 17874-76-9 ≥97.0%
250mg
 $57.0 2022-04-27
ChemScence
CS-0035737-1g
6-methoxycarbonylpyridine-3-carboxylic acid
 17874-76-9 ≥97.0%
1g
 $70.0 2022-04-27
ChemScence
CS-0035737-5g
6-methoxycarbonylpyridine-3-carboxylic acid
 17874-76-9 ≥97.0%
5g
 $270.0 2022-04-27
ChemScence
CS-0035737-25g
6-methoxycarbonylpyridine-3-carboxylic acid
 17874-76-9 ≥97.0%
25g
 $900.0 2022-04-27
Matrix Scientific
083396-250mg
6-(Methoxycarbonyl)nicotinic acid, 97%
 17874-76-9 97%
250mg
 $80.00 2023-09-09

6-(methoxycarbonyl)pyridine-3-carboxylic acid Related Literature

Additional information on 6-(methoxycarbonyl)pyridine-3-carboxylic acid

6-(Methoxycarbonyl)pyridine-3-carboxylic Acid (CAS No. 17874-76-9): Properties, Applications, and Market Insights

6-(Methoxycarbonyl)pyridine-3-carboxylic acid (CAS No. 17874-76-9) is a versatile organic compound with significant applications in pharmaceuticals, agrochemicals, and material science. This compound, also known as methyl 5-carboxypyridine-2-carboxylate, belongs to the pyridine carboxylic acid family, which is widely studied for its unique chemical properties and industrial relevance. In recent years, the demand for pyridine derivatives has surged due to their role in drug development and specialty chemicals.

The molecular formula of 6-(methoxycarbonyl)pyridine-3-carboxylic acid is C8H7NO4, with a molecular weight of 181.15 g/mol. Its structure features a pyridine ring substituted with both a methoxycarbonyl group and a carboxylic acid group, making it a valuable intermediate in organic synthesis. Researchers and manufacturers often seek this compound for its ability to participate in condensation reactions, esterifications, and other key transformations.

One of the most prominent applications of CAS 17874-76-9 is in the pharmaceutical industry, where it serves as a building block for active pharmaceutical ingredients (APIs). Its pyridine core is a common motif in drugs targeting neurological disorders, inflammation, and infectious diseases. With the growing focus on small molecule therapeutics, this compound has gained attention in drug discovery pipelines.

In agrochemicals, 6-(methoxycarbonyl)pyridine-3-carboxylic acid is utilized in the synthesis of herbicides and plant growth regulators. The carboxylic acid functionality allows for further derivatization, enabling the creation of compounds with tailored biological activities. As sustainable agriculture becomes a global priority, the demand for efficient and environmentally friendly agrochemicals has increased, further driving interest in this intermediate.

The material science sector also benefits from pyridine-3-carboxylic acid derivatives. These compounds can be incorporated into polymers, coatings, and electronic materials to enhance performance characteristics such as thermal stability and conductivity. With the rise of green chemistry initiatives, researchers are exploring eco-friendly synthesis routes for 6-(methoxycarbonyl)pyridine-3-carboxylic acid and its derivatives.

From a market perspective, the global demand for CAS 17874-76-9 has shown steady growth, particularly in regions with strong pharmaceutical and agrochemical industries. Suppliers and manufacturers are investing in scalable production methods to meet this demand while maintaining high purity standards. Quality control is critical, as impurities can affect downstream applications in sensitive industries.

Recent advancements in catalytic synthesis have improved the efficiency of producing 6-(methoxycarbonyl)pyridine-3-carboxylic acid. Innovations in flow chemistry and biocatalysis are reducing waste and energy consumption, aligning with the principles of green chemistry. These developments are particularly relevant given the increasing focus on sustainable manufacturing practices across the chemical industry.

For researchers working with pyridine carboxylic acids, proper handling and storage of 6-(methoxycarbonyl)pyridine-3-carboxylic acid are essential. While not classified as hazardous under standard conditions, it should be stored in a cool, dry place away from incompatible substances. Material Safety Data Sheets (MSDS) provide detailed guidance for safe laboratory practices.

The analytical characterization of 17874-76-9 typically involves techniques such as NMR spectroscopy, HPLC, and mass spectrometry. These methods ensure product quality and verify structural integrity, which is crucial for applications in regulated industries. Purity standards often exceed 98% for pharmaceutical-grade material.

Looking ahead, the future of 6-(methoxycarbonyl)pyridine-3-carboxylic acid appears promising. Its role in drug discovery, agrochemical innovation, and advanced materials continues to expand. As synthetic methodologies evolve and applications diversify, this compound is likely to remain an important tool for chemists and researchers worldwide.

For those sourcing CAS 17874-76-9, it's important to work with reputable suppliers who can provide comprehensive technical data and regulatory documentation. The market offers various grades of this compound, from research quantities to bulk industrial scale, catering to different application requirements.

In conclusion, 6-(methoxycarbonyl)pyridine-3-carboxylic acid represents an important class of heterocyclic compounds with wide-ranging utility. Its chemical versatility, combined with growing industrial demand, makes it a compound of significant interest across multiple sectors. Continued research into its properties and applications will undoubtedly uncover new opportunities for this valuable chemical intermediate.

17874-76-9 (6-(methoxycarbonyl)pyridine-3-carboxylic acid) Related Products

Recommended suppliers
Yunnanjiuzhen
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Yunnanjiuzhen
SHOCHEM(SHANGHAI) CO.,lTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
SHOCHEM(SHANGHAI) CO.,lTD
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangsu Xinsu New Materials Co., Ltd
Beyond Pharmaceutical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Amadis Chemical Company Limited