Cas no 178488-38-5 (ethyl 3-formylimidazo1,2-apyridine-2-carboxylate)

Ethyl 3-formylimidazo[1,2-a]pyridine-2-carboxylate is a versatile heterocyclic compound featuring both an aldehyde and an ester functional group. Its imidazopyridine core is a privileged scaffold in medicinal chemistry, offering potential applications in the synthesis of bioactive molecules and pharmaceuticals. The formyl group at the 3-position enables further derivatization through condensation or nucleophilic addition reactions, while the ethyl ester provides a handle for hydrolysis or transesterification. This compound is particularly valuable as a building block for constructing complex heterocyclic systems, such as fused polycyclic frameworks, due to its reactivity and structural flexibility. Its well-defined structure and functional group compatibility make it suitable for use in drug discovery and materials science research.
ethyl 3-formylimidazo1,2-apyridine-2-carboxylate structure
178488-38-5 structure
Product Name:ethyl 3-formylimidazo1,2-apyridine-2-carboxylate
CAS No:178488-38-5
MF:C11H10N2O3
MW:218.20870256424
MDL:MFCD09864098
CID:1107915
PubChem ID:10704014
Update Time:2025-11-02

ethyl 3-formylimidazo1,2-apyridine-2-carboxylate Chemical and Physical Properties

Names and Identifiers

    • 3-formyl-Imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester
    • DTXSID001229954
    • AKOS016352777
    • ethyl 3-formyl-imidazolo[1,2-a]pyridine-2-carboxylate
    • 178488-38-5
    • SCHEMBL1421022
    • DB-416354
    • ethyl 3-formylimidazo[1,2-a]pyridine-2-carboxylate
    • MFCD09864098
    • ZKUWBZQURLPJEQ-UHFFFAOYSA-N
    • ethyl 3-formylimidazo1,2-apyridine-2-carboxylate
    • MDL: MFCD09864098
    • Inchi: 1S/C11H10N2O3/c1-2-16-11(15)10-8(7-14)13-6-4-3-5-9(13)12-10/h3-7H,2H2,1H3
    • InChI Key: ZKUWBZQURLPJEQ-UHFFFAOYSA-N
    • SMILES: O(CC)C(C1=C(C=O)N2C=CC=CC2=N1)=O

Computed Properties

  • Exact Mass: 218.06914219g/mol
  • Monoisotopic Mass: 218.06914219g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 4
  • Complexity: 282
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.1
  • Topological Polar Surface Area: 60.7?2

ethyl 3-formylimidazo1,2-apyridine-2-carboxylate Pricemore >>

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Additional information on ethyl 3-formylimidazo1,2-apyridine-2-carboxylate

Comprehensive Guide to Ethyl 3-Formylimidazo[1,2-a]pyridine-2-carboxylate (CAS No. 178488-38-5)

Ethyl 3-formylimidazo[1,2-a]pyridine-2-carboxylate (CAS No. 178488-38-5) is a versatile heterocyclic compound widely used in pharmaceutical and agrochemical research. This compound belongs to the imidazopyridine family, known for its significant biological activity and synthetic utility. Researchers and industries value this compound for its unique structural features, making it a key intermediate in the development of novel drugs and functional materials.

The molecular structure of ethyl 3-formylimidazo[1,2-a]pyridine-2-carboxylate combines an imidazo[1,2-a]pyridine core with an ethyl ester and a formyl group, enhancing its reactivity and applicability in various chemical transformations. Its CAS No. 178488-38-5 ensures precise identification in scientific databases, facilitating research and regulatory compliance. The compound's stability under standard conditions and compatibility with common organic solvents make it a preferred choice for laboratory and industrial applications.

One of the most searched topics related to ethyl 3-formylimidazo[1,2-a]pyridine-2-carboxylate is its role in medicinal chemistry. Recent studies highlight its potential as a building block for kinase inhibitors and antimicrobial agents, addressing global health challenges such as antibiotic resistance. The rise of AI-driven drug discovery has further increased interest in this compound, as computational models predict its utility in designing next-generation therapeutics.

In addition to pharmaceutical applications, ethyl 3-formylimidazo[1,2-a]pyridine-2-carboxylate (CAS No. 178488-38-5) is explored in material science. Its conjugated system and functional groups enable the synthesis of organic semiconductors and luminescent materials, aligning with the growing demand for sustainable electronics. Researchers frequently inquire about its synthesis methods, with microwave-assisted and one-pot reactions being popular due to their efficiency and eco-friendliness.

The market for imidazo[1,2-a]pyridine derivatives is expanding, driven by their diverse applications. CAS No. 178488-38-5 is often referenced in patents and scientific publications, underscoring its commercial and academic relevance. Suppliers and manufacturers emphasize high-purity grades to meet the stringent requirements of drug development and advanced material synthesis.

For researchers seeking reliable data on ethyl 3-formylimidazo[1,2-a]pyridine-2-carboxylate, understanding its spectroscopic properties (e.g., NMR, IR, and MS) is crucial. These analytical details are frequently requested in online forums and databases, reflecting the compound's importance in quality control and structural verification. Collaborative platforms like PubChem and Reaxys provide accessible information, supporting innovation across disciplines.

Environmental and safety considerations for CAS No. 178488-38-5 are also trending topics. While the compound is not classified as hazardous, proper handling protocols—such as using personal protective equipment (PPE) and ensuring adequate ventilation—are recommended. Regulatory agencies like the FDA and EMA monitor its use in pharmaceuticals, ensuring compliance with global safety standards.

Future prospects for ethyl 3-formylimidazo[1,2-a]pyridine-2-carboxylate include its integration into green chemistry initiatives. Catalytic processes and biodegradable formulations are under investigation, responding to the demand for sustainable chemical practices. As industries prioritize eco-friendly solutions, this compound’s adaptability positions it as a valuable asset in circular economy models.

In summary, ethyl 3-formylimidazo[1,2-a]pyridine-2-carboxylate (CAS No. 178488-38-5) bridges multiple scientific domains, from drug discovery to advanced materials. Its structural versatility, coupled with emerging applications, ensures its prominence in research and industry. By staying updated on synthesis innovations and regulatory trends, stakeholders can maximize its potential while adhering to safety and sustainability goals.

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