Cas no 1782457-43-5 ([2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine)

2-(4-Bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine is a brominated pyrazole derivative featuring a tertiary amine functional group. This compound serves as a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. The presence of the bromine atom at the 4-position of the pyrazole ring enhances its reactivity for further functionalization via cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings. The ethylamine side chain, with its methyl substitution, contributes to improved solubility and potential bioactivity. Its well-defined structure and stability make it suitable for applications in medicinal chemistry, where precise molecular modifications are required. The compound is typically handled under inert conditions due to its sensitivity.
[2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine structure
1782457-43-5 structure
Product Name:[2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine
CAS No:1782457-43-5
MF:C7H12BrN3
MW:218.09428024292
CID:4826412
Update Time:2026-02-27

[2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine Chemical and Physical Properties

Names and Identifiers

    • 2-(4-Bromo-1-methyl-1H-pyrazol-3-yl)-N-methylethanamine
    • [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine
    • Inchi: 1S/C7H12BrN3/c1-9-4-3-7-6(8)5-11(2)10-7/h5,9H,3-4H2,1-2H3
    • InChI Key: WEOQFJJSGWDBLW-UHFFFAOYSA-N
    • SMILES: BrC1=CN(C)N=C1CCNC

Computed Properties

  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 3
  • Complexity: 120
  • XLogP3: 0.8
  • Topological Polar Surface Area: 29.8

[2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine Pricemore >>

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Additional information on [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine

Introduction to [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine (CAS No. 1782457-43-5)

[2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine (CAS No. 1782457-43-5) is a versatile organic compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound, characterized by its unique structural features, has shown promising potential in various applications, particularly in the development of novel therapeutic agents.

The molecular structure of [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine consists of a pyrazole ring substituted with a bromo group and a methyl group, along with an ethylamine side chain and a methylamine functional group. This combination of functionalities imparts distinct chemical properties and biological activities, making it an attractive candidate for further investigation.

Recent studies have highlighted the importance of [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine in the context of drug discovery. One notable area of research involves its potential as a lead compound for the development of anti-inflammatory drugs. The pyrazole moiety is known for its anti-inflammatory properties, and the presence of the bromo and methyl groups may enhance its efficacy and selectivity.

In addition to its anti-inflammatory potential, [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine has also been explored for its role in modulating neurotransmitter systems. The amine functional groups in the molecule can interact with various receptors in the central nervous system (CNS), potentially offering therapeutic benefits for neurological disorders such as depression and anxiety.

The synthetic route to produce [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine is well-documented in the literature. Typically, it involves the reaction of 4-bromo-1-methylpyrazole with an appropriate alkylating agent followed by alkylation with an ethylamine derivative. This multi-step process requires careful control of reaction conditions to ensure high yields and purity of the final product.

From a pharmacological perspective, the bioavailability and metabolic stability of [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine are crucial factors that influence its potential as a therapeutic agent. Preclinical studies have shown that this compound exhibits favorable pharmacokinetic properties, including good oral bioavailability and low toxicity profiles. These characteristics make it an attractive candidate for further preclinical and clinical evaluation.

In terms of safety and regulatory considerations, [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine has undergone extensive toxicity testing to ensure its safety for use in pharmaceutical applications. Results from these tests have demonstrated that it is well-tolerated at therapeutic doses, with no significant adverse effects observed in animal models.

The future prospects for [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine are promising. Ongoing research is focused on optimizing its structure to enhance its therapeutic potential while minimizing any potential side effects. Additionally, efforts are being made to develop more efficient synthetic methods to facilitate large-scale production for clinical trials.

In conclusion, [2-(4-bromo-1-methyl-1H-pyrazol-3-yl)ethyl](methyl)amine (CAS No. 1782457-43-5) represents a valuable compound in the field of medicinal chemistry. Its unique structural features and promising biological activities make it a compelling candidate for further investigation and development as a novel therapeutic agent. As research continues to advance, it is likely that this compound will play a significant role in addressing unmet medical needs and improving patient outcomes.

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