Cas no 1782349-45-4 (1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine)

1-(Piperidin-2-ylmethyl)-1H-pyrazol-4-amine is a heterocyclic compound featuring a pyrazole core linked to a piperidine moiety via a methylene bridge. This structure imparts versatility in pharmaceutical and agrochemical applications, particularly as a building block for bioactive molecules. The amine group at the 4-position of the pyrazole ring enhances reactivity, enabling further functionalization, while the piperidine component contributes to conformational rigidity and potential binding affinity. Its balanced lipophilicity and polarity make it suitable for drug discovery, particularly in targeting central nervous system (CNS) receptors or enzyme inhibitors. The compound’s synthetic accessibility and modularity further underscore its utility in medicinal chemistry research.
1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine structure
1782349-45-4 structure
Product Name:1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine
CAS No:1782349-45-4
MF:C9H16N4
MW:180.250141143799
CID:4613778
PubChem ID:84732322
Update Time:2025-06-03

1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine Chemical and Physical Properties

Names and Identifiers

    • 1H-Pyrazol-4-amine, 1-(2-piperidinylmethyl)-
    • 1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine
    • Inchi： 1S/C9H16N4/c10-8-5-12-13(6-8)7-9-3-1-2-4-11-9/h5-6,9,11H,1-4,7,10H2
    • InChI Key： WEPLGETXCSLWIF-UHFFFAOYSA-N
    • SMILES： N1(CC2CCCCN2)C=C(N)C=N1

1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Enamine
EN300-176042-0.05g
1-[(piperidin-2-yl)methyl]-1H-pyrazol-4-amine
 1782349-45-4 95%
0.05g
 $179.0 2023-09-20
Enamine
EN300-176042-0.1g
1-[(piperidin-2-yl)methyl]-1H-pyrazol-4-amine
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Enamine
EN300-176042-0.25g
1-[(piperidin-2-yl)methyl]-1H-pyrazol-4-amine
 1782349-45-4 95%
0.25g
 $383.0 2023-09-20
Enamine
EN300-176042-0.5g
1-[(piperidin-2-yl)methyl]-1H-pyrazol-4-amine
 1782349-45-4 95%
0.5g
 $601.0 2023-09-20
Enamine
EN300-176042-1.0g
1-[(piperidin-2-yl)methyl]-1H-pyrazol-4-amine
 1782349-45-4 95%
1g
 $770.0 2023-05-23
Enamine
EN300-176042-2.5g
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 1782349-45-4 95%
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Enamine
EN300-176042-5.0g
1-[(piperidin-2-yl)methyl]-1H-pyrazol-4-amine
 1782349-45-4 95%
5g
 $2235.0 2023-05-23
Enamine
EN300-176042-10.0g
1-[(piperidin-2-yl)methyl]-1H-pyrazol-4-amine
 1782349-45-4 95%
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TRC
B450230-10mg
1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine
 1782349-45-4
10mg
 $ 50.00 2022-06-07
TRC
B450230-50mg
1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine
 1782349-45-4
50mg
 $ 185.00 2022-06-07

1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine Related Literature

Additional information on 1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine

1-(Piperidin-2-ylmethyl)-1H-pyrazol-4-amine: A Comprehensive Overview

The compound 1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine, identified by the CAS number 1782349-45-4, has garnered significant attention in the field of organic chemistry and pharmacology. This molecule is a derivative of pyrazole, a five-membered aromatic heterocycle, which has been extensively studied for its potential in drug discovery. The integration of a piperidine ring into its structure introduces unique properties that make it a promising candidate for various applications.

Recent studies have highlighted the importance of pyrazole derivatives in medicinal chemistry due to their ability to interact with various biological targets. The piperidine moiety in this compound contributes to its lipophilicity, enhancing its bioavailability and pharmacokinetic properties. This makes it particularly relevant for the development of orally administered drugs.

The synthesis of 1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine involves a multi-step process that combines traditional organic synthesis techniques with modern catalytic methods. Researchers have explored various routes, including nucleophilic substitution and coupling reactions, to optimize the yield and purity of this compound. These advancements have been documented in recent publications, underscoring the compound's potential for large-scale production.

In terms of pharmacological activity, this compound has shown promising results in preliminary assays. It exhibits moderate to high affinity for certain G-protein coupled receptors (GPCRs), which are critical targets in the treatment of central nervous system disorders. Additionally, studies have indicated that it may possess anti-inflammatory properties, making it a potential candidate for anti-inflammatory drug development.

The structural versatility of 1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amine allows for further functionalization, enabling researchers to explore its potential in other therapeutic areas. For instance, modifications to the piperidine ring or the pyrazole core could lead to compounds with enhanced selectivity or reduced off-target effects.

In conclusion, the compound CAS 1782349-45-4, or 1-(piperidin-2-ylmethyl)-1H-pyrazol-4-amino, represents a valuable addition to the arsenal of bioactive molecules available for drug discovery. Its unique chemical structure, combined with recent advances in synthesis and pharmacological evaluation, positions it as a key player in future therapeutic developments.

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