Cas no 1781268-45-8 ((4-hydroxyphenyl)methanesulfonamide)

(4-Hydroxyphenyl)methanesulfonamide is a sulfonamide derivative characterized by the presence of a hydroxyphenyl functional group. This compound is of interest in medicinal chemistry and pharmaceutical research due to its potential as a building block for drug development, particularly in the synthesis of enzyme inhibitors or receptor modulators. The hydroxyphenyl moiety enhances solubility and offers a site for further functionalization, while the sulfonamide group contributes to binding interactions with biological targets. Its well-defined structure and reactivity make it a valuable intermediate for exploring structure-activity relationships. The compound is typically handled under standard laboratory conditions, with purity and stability being key considerations for research applications.
(4-hydroxyphenyl)methanesulfonamide structure
1781268-45-8 structure
Product Name:(4-hydroxyphenyl)methanesulfonamide
CAS No:1781268-45-8
MF:C7H9NO3S
MW:187.216260671616
CID:5925209
PubChem ID:67410560
Update Time:2025-10-18

(4-hydroxyphenyl)methanesulfonamide Chemical and Physical Properties

Names and Identifiers

    • (4-hydroxyphenyl)methanesulfonamide
    • SCHEMBL2444207
    • MRIPEESUXRBPND-UHFFFAOYSA-N
    • EN300-2004200
    • 1781268-45-8
    • Inchi: 1S/C7H9NO3S/c8-12(10,11)5-6-1-3-7(9)4-2-6/h1-4,9H,5H2,(H2,8,10,11)
    • InChI Key: MRIPEESUXRBPND-UHFFFAOYSA-N
    • SMILES: S(CC1C=CC(=CC=1)O)(N)(=O)=O

Computed Properties

  • Exact Mass: 187.03031432g/mol
  • Monoisotopic Mass: 187.03031432g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 224
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.2
  • Topological Polar Surface Area: 88.8?2

(4-hydroxyphenyl)methanesulfonamide Pricemore >>

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