• 1. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
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  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Pyrazoles

Comprehensive Overview of 2-(1-methyl-1H-pyrazol-3-yl)ethan-1-ol (CAS No. 177940-19-1)

2-(1-methyl-1H-pyrazol-3-yl)ethan-1-ol (CAS No. 177940-19-1) is a versatile organic compound that has garnered significant attention in pharmaceutical and agrochemical research. This compound, characterized by its pyrazole core and hydroxyl-functionalized side chain, serves as a key intermediate in the synthesis of various biologically active molecules. Its unique structural features make it a valuable building block for drug discovery and material science applications.

The growing interest in heterocyclic compounds like 2-(1-methyl-1H-pyrazol-3-yl)ethan-1-ol stems from their broad utility in medicinal chemistry. Researchers frequently search for "pyrazole derivatives in drug design" or "CAS 177940-19-1 applications," reflecting the compound's relevance in developing kinase inhibitors and anti-inflammatory agents. Recent studies highlight its potential in modulating protein-protein interactions, a hot topic in targeted therapy development.

From a synthetic chemistry perspective, 2-(1-methyl-1H-pyrazol-3-yl)ethan-1-ol offers excellent functional group compatibility. Its hydroxyl group permits straightforward derivatization through esterification or etherification reactions, while the 1-methylpyrazole moiety provides metabolic stability - a property highly sought after in "bioactive compound optimization" strategies. The compound's logP value and hydrogen bonding capacity make it particularly interesting for researchers investigating "molecular solubility enhancement" techniques.

In material science applications, this compound has shown promise as a precursor for coordination polymers. The nitrogen atoms in the pyrazole ring can act as ligands for metal ions, creating frameworks with potential applications in gas storage or catalysis. This aligns with current trends in "green chemistry solutions" and "sustainable material development," making CAS 177940-19-1 relevant to environmental research initiatives.

The analytical characterization of 2-(1-methyl-1H-pyrazol-3-yl)ethan-1-ol typically involves advanced techniques such as NMR spectroscopy and mass spectrometry. These methods confirm the compound's high purity (>98%), a critical parameter for researchers searching for "high-quality chemical intermediates." The compound's stability under various pH conditions makes it suitable for "formulation development" studies, particularly in pharmaceutical applications.

Recent patent literature reveals innovative applications of 2-(1-methyl-1H-pyrazol-3-yl)ethan-1-ol in electronic materials. Its conjugated system shows potential in "organic semiconductor" development, addressing the growing demand for "flexible electronics materials." This unexpected application area demonstrates the compound's versatility beyond traditional medicinal chemistry uses.

From a safety perspective, proper handling of 2-(1-methyl-1H-pyrazol-3-yl)ethan-1-ol requires standard laboratory precautions. While not classified as hazardous under current regulations, researchers often inquire about "chemical handling best practices" and "laboratory safety protocols" when working with such intermediates. The compound's environmental fate and biodegradation profile remain active areas of investigation in "green chemistry assessment" programs.

The commercial availability of CAS 177940-19-1 has increased significantly in recent years, reflecting its growing importance in chemical research. Suppliers frequently highlight its application in "custom synthesis projects" and "medicinal chemistry libraries." The compound's relatively stable shelf life under recommended storage conditions makes it practical for inventory maintenance in research facilities.

Future research directions for 2-(1-methyl-1H-pyrazol-3-yl)ethan-1-ol may explore its potential in "click chemistry" applications or as a scaffold for "multifunctional materials." The continuous evolution of synthetic methodologies ensures this compound will remain relevant in addressing contemporary challenges in chemical research and development.

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