• 1. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 2. Emerging 2D hybrid nanomaterials: towards enhanced sensitive and selective conductometric gas sensors at room temperature
  Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
• 3. Dissociative electron attachment to HGaF4 Lewis–Br?nsted superacid
  Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
• 4. Examination of deposit in commercial diluted phosphoric acid
  Analyst, 1880,5, 146-147
• 5. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161

Methyl 3-Amino-2,2-Dimethylpropanoate Hydrochloride: A Comprehensive Overview

Methyl 3-amino-2,2-dimethylpropanoate hydrochloride, with the CAS number 177269-37-3, is a compound of significant interest in the fields of organic chemistry and pharmacology. This compound is a derivative of propanoic acid, featuring a methyl group attached to the third carbon and a hydrochloride salt. The structure of this compound is characterized by its branched alkyl chain and the presence of an amino group, which contributes to its unique chemical properties and potential applications.

The synthesis of methyl 3-amino-2,2-dimethylpropanoate hydrochloride involves a series of carefully controlled reactions. Typically, the starting material is a suitable amino alcohol or amine derivative, which undergoes alkylation or acylation to introduce the methyl group and the amino functionality. The hydrochloride salt is formed by protonating the amino group under acidic conditions. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly syntheses of this compound, aligning with the growing demand for sustainable chemical processes.

One of the most promising applications of methyl 3-amino-2,2-dimethylpropanoate hydrochloride lies in its use as an intermediate in drug development. The compound's structure makes it an ideal candidate for modifying bioactive molecules, enhancing their pharmacokinetic properties such as solubility and bioavailability. For instance, researchers have explored its role in the synthesis of peptide-based drugs and antibiotics, where it serves as a key building block.

Recent studies have also highlighted the potential of this compound in agricultural chemistry. Its ability to act as a growth regulator for plants has been investigated in controlled experiments. By incorporating methyl 3-amino-2,2-dimethylpropanoate hydrochloride into fertilizers or pesticides, farmers could potentially enhance crop yields while reducing environmental impact. These findings underscore the versatility of this compound across multiple industries.

In terms of toxicity and safety profiles, methyl 3-amino-2,2-dimethylpropanoate hydrochloride has been subjected to rigorous testing. According to recent research published in toxicological journals, the compound exhibits low acute toxicity when administered orally or dermally. However, prolonged exposure or high doses may lead to adverse effects on liver function. These findings emphasize the importance of proper handling and storage guidelines for this compound.

From an environmental perspective, the biodegradability of methyl 3-amino-2,2-dimethylpropanoate hydrochloride has been a topic of interest. Studies conducted under simulated environmental conditions indicate that the compound undergoes rapid microbial degradation under aerobic conditions. This property is particularly advantageous for its use in agricultural applications where minimizing environmental footprint is crucial.

Looking ahead, ongoing research aims to explore novel synthetic pathways for methyl 3-amino-2,2-dimethylpropanoate hydrochloride that leverage renewable feedstocks and green chemistry principles. Additionally, investigations into its potential as a precursor for advanced materials such as polymers or nanoparticles are underway. These developments highlight the compound's role as a versatile tool in modern chemistry.

In conclusion, methyl 3-amino-2,2-dimethylpropanoate hydrochloride (CAS No. 177269-37-3) stands out as a multifaceted chemical entity with applications spanning drug development, agriculture, and materials science. Its unique chemical properties and favorable safety profile make it an invaluable asset in contemporary research and industry practices.

• 917894-31-6(Propanoic acid, 3-amino-2-methyl-, ethyl ester, (2S)-)
• 8024-05-3(Ethyl 3-amino-2,2-dimethylpropanoate hydrochloride)
• 25307-82-8(Methyl 3-amino-2,2-dimethylpropanoate)
• 59193-77-0(Ethyl 3-amino-2,2-dimethylpropanoate)
• 22560-81-2(Ethyl 3-amino-2-methylpropanoate)
• 88512-06-5(methyl 3-amino-2-methylpropanoate hydrochloride)
• 8028-45-3(Ethyl 3-amino-2,2-dimethylpropanoate hydrochloride)
• 14678-48-9(methyl 3-amino-2-methylpropanoate)
• 159029-33-1(Methyl 3-amino-2-(aminomethyl)propanoate)
• 80253-38-9(ethyl 3-amino-2,2-dimethyl-propanoate;hydrochloride)