Cas no 17659-78-8 (N-(3-Methylbutyl)adenosine)

N-(3-Methylbutyl)adenosine is a modified nucleoside derivative characterized by the substitution of a 3-methylbutyl group at the N-position of adenosine. This structural modification enhances its potential utility in biochemical and pharmacological research, particularly in studies involving nucleoside transport, enzyme interactions, and receptor binding. The compound's lipophilic side chain may improve membrane permeability, making it valuable for probing adenosine-related pathways in cellular systems. Its synthetic versatility allows for further functionalization, enabling tailored applications in medicinal chemistry and molecular biology. High-purity grades ensure reproducibility in experimental settings, supporting rigorous scientific investigation. This derivative serves as a specialized tool for advancing understanding of adenosine signaling mechanisms.

N-(3-Methylbutyl)adenosine structure

Product Name:N-(3-Methylbutyl)adenosine

CAS No:17659-78-8

MF:C₁₅H₂₃N₅O₄

MW:337.374222993851

CID:50833

PubChem ID:87216

Update Time:2025-11-02

N-(3-Methylbutyl)adenosine Chemical and Physical Properties

Names and Identifiers

- N-(3-Methylbutyl)adenosine
- N-Isopentyladenosine
- Adenosine,N-(3-methylbutyl)
- N6-(3-methyl-butyl)-adenosine
- N6-Isopentyladenosine
- Einecs 241-638-1
- Adenosine, N-(3-methylbutyl)-
- CHEMBL1290747
- NS00053485
- (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(3-methylbutylamino)purin-9-yl]oxolane-3,4-diol
- N-(3-Methylbutyl)-9-pentofuranosyl-9H-purin-6-amine
- SCHEMBL547462
- 17659-78-8
- (2R,3S,4R,5R)-2-(hydroxymethyl)-5-{6-[(3-methylbutyl)amino]-9H-purin-9-yl}oxolane-3,4-diol
- (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(isopentylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
- DTXSID40938818
- Inchi： 1S/C15H23N5O4/c1-8(2)3-4-16-13-10-14(18-6-17-13)20(7-19-10)15-12(23)11(22)9(5-21)24-15/h6-9,11-12,15,21-23H,3-5H2,1-2H3,(H,16,17,18)/t9-,11-,12-,15-/m1/s1
- InChI Key： AYGMJXUCSYBOMJ-SDBHATRESA-N
- SMILES： O1[C@H](CO)[C@H]([C@H]([C@@H]1N1C=NC2C(=NC=NC1=2)NCCC(C)C)O)O

Computed Properties

Exact Mass: 337.17500
Monoisotopic Mass: 337.175
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 8
Heavy Atom Count: 24
Rotatable Bond Count: 6
Complexity: 415
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 4
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 1.3
Topological Polar Surface Area: 126?2

Experimental Properties

Density: 1.57
Boiling Point: 632.9°Cat760mmHg
Flash Point: 336.5°C
Refractive Index: 1.708
PSA: 125.55000
LogP: -0.03120

N-(3-Methylbutyl)adenosine Pricemore >>

Related Categories	No.	Product Name	Cas No.	Specification	Price	update time
TRC	N236870-1mg	N-(3-Methylbutyl)adenosine	17659-78-8	1mg	$ 65.00	2022-06-03
TRC	N236870-2.5mg	N-(3-Methylbutyl)adenosine	17659-78-8	2.5mg	$ 80.00	2022-06-03
TRC	N236870-5mg	N-(3-Methylbutyl)adenosine	17659-78-8	5mg	$ 210.00	2022-06-03
A2B Chem LLC	AA99288-5mg	Adenosine, N-(3-methylbutyl)-	17659-78-8	5mg	$286.00	2024-04-20

N-(3-Methylbutyl)adenosine Suppliers

NewCan Biotech Limited

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(CAS:17659-78-8)N-(3-Methylbutyl)adenosine

Order Number:NC10645

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Quantity:10g

Purity:97%

Pricing Information Last Updated:Friday, 18 July 2025 16:11

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Email:[email protected]

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Additional information on N-(3-Methylbutyl)adenosine

N-(3-Methylbutyl)adenosine (CAS No. 17659-78-8): A Comprehensive Overview

N-(3-Methylbutyl)adenosine (CAS No. 17659-78-8) is a modified nucleoside derivative that has garnered significant attention in biochemical and pharmaceutical research. This compound, structurally related to adenosine, features a 3-methylbutyl group attached to the nitrogen atom of the adenine base. Its unique structure makes it a valuable candidate for studying nucleoside metabolism, receptor interactions, and potential therapeutic applications.

The growing interest in N-(3-Methylbutyl)adenosine is partly driven by the broader scientific community's focus on modified nucleosides and their roles in cellular processes. Researchers are particularly intrigued by its potential to modulate adenosine receptors, which play critical roles in cardiovascular, neurological, and immune system functions. Recent studies have explored its interactions with A1 and A2A adenosine receptors, making it a subject of interest for drug development targeting conditions like inflammation and neurodegenerative diseases.

One of the key advantages of N-(3-Methylbutyl)adenosine is its stability compared to natural adenosine, which is rapidly metabolized in vivo. This property enhances its utility in experimental settings, allowing for more accurate assessments of its biological effects. Additionally, its synthetic accessibility has made it a popular choice for structure-activity relationship (SAR) studies, where researchers aim to optimize nucleoside-based therapeutics.

In the context of current research trends, N-(3-Methylbutyl)adenosine is often discussed alongside other modified nucleosides such as N6-substituted adenosines. These compounds are being investigated for their potential to improve drug delivery systems, enhance bioavailability, and reduce side effects. The compound's lipophilic 3-methylbutyl side chain may also contribute to better membrane permeability, a desirable trait for orally administered drugs.

From a commercial perspective, the demand for N-(3-Methylbutyl)adenosine has been steadily increasing, particularly among pharmaceutical companies and academic research institutions. Its applications span from basic biochemical research to high-throughput screening for novel therapeutics. Suppliers often highlight its high purity and compatibility with various analytical techniques, including HPLC and mass spectrometry, as key selling points.

For researchers looking to explore the potential of N-(3-Methylbutyl)adenosine, it is essential to consider its solubility and storage conditions. The compound is typically soluble in organic solvents like DMSO and ethanol, making it suitable for in vitro assays. Proper storage at -20°C is recommended to maintain its stability over extended periods.

Looking ahead, the future of N-(3-Methylbutyl)adenosine research appears promising, with ongoing studies investigating its role in epigenetic modifications and signal transduction pathways. As the scientific community continues to uncover the multifaceted roles of nucleosides in health and disease, this compound is likely to remain a focal point of innovation and discovery.

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