Cas no 17652-24-3 (Prednisolone 17,21-Diacetate)
Prednisolone 17,21-Diacetate is a synthetic glucocorticoid derivative of prednisolone, characterized by the acetylation of hydroxyl groups at the 17 and 21 positions. This modification enhances its lipophilicity, improving membrane permeability and bioavailability. The compound exhibits potent anti-inflammatory, immunosuppressive, and anti-allergic properties, making it valuable in pharmaceutical research and therapeutic applications. Its stability and controlled metabolic profile allow for prolonged activity compared to non-esterified analogs. Prednisolone 17,21-Diacetate is commonly utilized in experimental studies and formulations requiring sustained glucocorticoid effects. The diacetate form also facilitates tailored drug delivery systems, offering versatility in preclinical and clinical contexts.
Prednisolone 17,21-Diacetate structure
Product Name:Prednisolone 17,21-Diacetate
CAS No:17652-24-3
MF:C25H32O7
MW:444.517388343811
CID:3161723
PubChem ID:14233395
Update Time:2025-06-08
Prednisolone 17,21-Diacetate Chemical and Physical Properties
Names and Identifiers
-
- [2-[(8S,9S,10R,11S,13S,14S,17R)-17-acetyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
- 11beta-hydroxy-17,21-diacetoxy-3,20-dioxo-1, 4-pregnadiene
- Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-11-hydroxy-, (11beta)-
- 17652-24-3
- VWLTWMGSJXSKQJ-WEXULQILSA-N
- SCHEMBL2299113
- acetic acid (8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxy-acetyl)-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester
- DTXSID30170149
- AKOS030255018
- DTXCID7092640
- 17alpha,21-diacetoxy-11beta-hydroxy-1,4- pregnadiene-3,20-dione
- Prednisolone 17,21-diacetate
- 17alpha,21-diacetoxy-11beta-hydroxy-1,4-pregnadiene-3,20-dione
- Prednisolone 17,21-Diacetate
-
- Inchi： 1S/C25H32O7/c1-14(26)31-13-21(30)25(32-15(2)27)10-8-19-18-6-5-16-11-17(28)7-9-23(16,3)22(18)20(29)12-24(19,25)4/h7,9,11,18-20,22,29H,5-6,8,10,12-13H2,1-4H3/t18-,19-,20-,22+,23-,24-,25-/m0/s1
- InChI Key： VWLTWMGSJXSKQJ-WEXULQILSA-N
- SMILES： O(C(C)=O)[C@]1(C(COC(C)=O)=O)CC[C@H]2[C@@H]3CCC4=CC(C=C[C@]4(C)[C@H]3[C@H](C[C@@]21C)O)=O
Computed Properties
- Exact Mass: 444.21480336Da
- Monoisotopic Mass: 444.21480336Da
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 7
- Heavy Atom Count: 32
- Rotatable Bond Count: 6
- Complexity: 933
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 7
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3
- Topological Polar Surface Area: 107?2
Prednisolone 17,21-Diacetate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | P703790-10mg |
Prednisolone 17,21-Diacetate |
17652-24-3 | 10mg |
$133.00 | 2023-05-17 | ||
| TRC | P703790-25mg |
Prednisolone 17,21-Diacetate |
17652-24-3 | 25mg |
$259.00 | 2023-05-17 | ||
| TRC | P703790-100mg |
Prednisolone 17,21-Diacetate |
17652-24-3 | 100mg |
$758.00 | 2023-05-17 | ||
| TRC | P703790-250mg |
Prednisolone 17,21-Diacetate |
17652-24-3 | 250mg |
$1516.00 | 2023-05-17 |
Prednisolone 17,21-Diacetate Related Literature
-
Xiaofeng Lin RSC Adv., 2016,6, 9002-9006
-
3. An amorphous lanthanum–iridium solid solution with an open structure for efficient water splitting?Wei Sun,Chenglong Ma,Xinlong Tian,Jianjun Liao,Ji Yang,Chengjun Ge,Weiwei Huang J. Mater. Chem. A, 2020,8, 12518-12525
-
Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
Related Categories
- Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Steroids and steroid derivatives Gluco/mineralocorticoids, progestogins and derivatives
- Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Steroids and steroid derivatives Pregnane steroids Gluco/mineralocorticoids, progestogins and derivatives
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